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Key transport systems fuel rapid E. coli growth in UTIs

Through a quirk of anatomy, women are especially prone to urinary tract infections, with almost half dealing with one at some point in their lives.

3 May 2024

Researchers highlight critical need for more effective treatments for women with bacterial vaginosis

Bacterial Vaginosis (BV) affects about one-quarter of reproductive-age women and is linked to adverse health outcomes, such as increased HIV risk.

2 May 2024

Glycoengineered stem cells enhance brain recovery after cardiac arrest, study finds

Researchers at the University of Maryland School of Medicine have identified an innovation in stem cell therapy to regenerate neural cells in the brain after cardiac arrest in an animal model.

2 May 2024

Rapamycin shows promise in slowing Alzheimer's disease progression linked to seizures

Protein imbalances that increase brain cell excitability may explain why individuals with Alzheimer's disease (AD) who also experience seizures demonstrate more rapid cognitive decline than those who do not experience seizures.

2 May 2024

New brain connectivity maps offer insights into human consciousness

In a paper titled, "Multimodal MRI reveals brainstem connections that sustain wakefulness in human consciousness," published today in Science Translational Medicine, a group of researchers at Massachusetts General Hospital, a founding member of the Mass General Brigham healthcare system, and Boston Children's Hospital, created a connectivity map of a brain network that they propose is critical to human consciousness.

2 May 2024

Study uncovers molecular mechanism linking nonsense-mediated RNA decay to microcephaly

Nonsense-mediated RNA decay, or NMD, is an evolutionarily conserved molecular mechanism in which potentially defective messenger RNAs, or mRNAs (genetic material that instructs the body on how to make proteins), are degraded.

1 May 2024

Machine learning tool can speed the diagnosis of undiagnosed patients with rare immune disorders

Researchers say a machine learning tool can identify many patients with rare, undiagnosed diseases years earlier, potentially improving outcomes and reducing cost and morbidity. The findings, led by researchers at UCLA Health, are described in Science Translational Medicine.

1 May 2024

Genes affecting worm behavior found to be relevant to neurological disease in humans

As an undergraduate student in The University of Texas at Arlington's Honors College, Hannah Selvarathinam knew she wanted to conduct research. Near the end of her first year at UTA, the Keller native reached out to the lab of biology Assistant Professor Piya Ghose.

30 Apr 2024

Progression of subtle CT abnormalities in smokers predicts acute respiratory disease

Smokers who have small abnormalities on their CT scans that grow over time have a greater likelihood of experiencing acute respiratory disease events, according to a new study published today in Radiology, a journal of the Radiological Society of North America.

30 Apr 2024

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

Infectious diseases caused by pathogenic strains of bacteria are a global cause of morbidity and mortality. Hospital-acquired infections caused by Klebsiella pneumonia and Pseudomonas aeruginosa were found vulnerable during the COVID-19 pandemic.

29 Apr 2024

Genetic associations of key genes in breast cancer pathogenesis

Breast cancer remains a significant global health concern, warranting further exploration into its genetic basis and potential therapeutic targets.

29 Apr 2024

Benefits and challenges of integrating nursing home residents into clinical trials

Clinical trials are constantly being designed and study participants enrolled to determine if medical treatments and therapies are safe and effective.

29 Apr 2024

Study shows link between air pollution, stress, and heart health risk

A study in more than 3,000 US counties, with 315 million residents, has suggested that air pollution is linked with stress and depression, putting under-65-year-olds at increased risk of dying from cardiovascular disease.

26 Apr 2024

Study suggests a common brain network exists between heart rate deceleration and depression

A new study by researchers at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, suggests a common brain network exists between heart rate deceleration and depression.

26 Apr 2024

Research reveals mortality disparities among sexual minority women

Compared to heterosexual women, bisexual women died 37% sooner and lesbian women 20% sooner, according to results from one of the largest studies to examine sexual orientation-related inequities in mortality and the first to differentiate between lesbians and bisexual women.

25 Apr 2024

Opportunities and limitations of using a large language model to respond to patient messages

A new study by investigators from Mass General Brigham demonstrates that large language models (LLMs), a type of generative AI, may help reduce physician workload and improve patient education when used to draft replies to patient messages.

24 Apr 2024

MSU team creates a promising vaccine candidate for antibiotic-resistant bacteria

Driven by the overuse of antimicrobials, pathogens are quickly building up resistances to once-successful treatments.

24 Apr 2024

$4.8 million grant supports research on TDP-43 misfolding in neurodegenerative diseases

A new $4.8 million grant will support researchers from Indiana University School of Medicine and the Medical Research Council Laboratory of Molecular Biology to study how human neurodegenerative diseases are affected by the misfolding of the protein TDP-43.

23 Apr 2024

Liver cells effectively serve as immune checkpoint regulating anti-cancer immunity

Liver inflammation, a common side-effect of cancers elsewhere in the body, has long been associated with worse cancer outcomes and more recently associated with poor response to immunotherapy.

22 Apr 2024

Boosted immunity: Study reveals longevity of COVID-19 booster shots

Thinking about getting a spring-time booster shot? A new study coming out of York University's Centre for Disease Modelling in the Faculty of Science shows that immunity after a COVID-19 booster lasts much longer than the primary series alone.

18 Apr 2024

Medical School News and Research

Key transport systems fuel rapid E. coli growth in UTIs

Researchers highlight critical need for more effective treatments for women with bacterial vaginosis

Glycoengineered stem cells enhance brain recovery after cardiac arrest, study finds

Rapamycin shows promise in slowing Alzheimer's disease progression linked to seizures

New brain connectivity maps offer insights into human consciousness

Study uncovers molecular mechanism linking nonsense-mediated RNA decay to microcephaly

Machine learning tool can speed the diagnosis of undiagnosed patients with rare immune disorders

Genes affecting worm behavior found to be relevant to neurological disease in humans

Progression of subtle CT abnormalities in smokers predicts acute respiratory disease

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

Genetic associations of key genes in breast cancer pathogenesis

Benefits and challenges of integrating nursing home residents into clinical trials

Study shows link between air pollution, stress, and heart health risk

Study suggests a common brain network exists between heart rate deceleration and depression

Research reveals mortality disparities among sexual minority women

Opportunities and limitations of using a large language model to respond to patient messages

MSU team creates a promising vaccine candidate for antibiotic-resistant bacteria

$4.8 million grant supports research on TDP-43 misfolding in neurodegenerative diseases

Liver cells effectively serve as immune checkpoint regulating anti-cancer immunity

Boosted immunity: Study reveals longevity of COVID-19 booster shots

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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