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Study reveals impact of Mediator protein complex on cell division regulation

Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide.

3 May 2024

Breakthrough study identifies potential treatments for influenza-associated encephalopathy

It might start simply, with a cough or sneeze…but in some cases, the flu virus can make its way to your brain, causing serious symptoms or even death through a disease known as influenza-associated encephalopathy (IAE).

3 May 2024

Researchers identify key molecular alterations from endurance exercise that could combat chronic diseases

A whole-organism molecular map of the temporal effects of endurance training in rats.

3 May 2024

Study highlights the role of dynamic DNA structures in memory consolidation

An international collaborative research team, including scientists from UQ's Queensland Brain Institute (QBI), has discovered a novel mechanism underlying memory involving rapid changes in a specific DNA structure.

2 May 2024

New drug candidate reverses obesity in mice by transforming liver metabolism

A mitochondrial transcription inhibitor (IMT) shifted metabolism in high-fat diet mice toward fatty acid oxidation, leading to weight loss, reduced liver fat, and improved glucose tolerance.

1 May 2024

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Currently, most therapies for allergic diseases require lifelong treatment. Allergic reactions, characterized by ongoing (type 2) inflammation in response to chronic antigen exposure, underlie many chronic diseases in humans, including asthma, atopic dermatitis, ulcerative colitis and more.

30 Apr 2024

Unlocking the mechanisms of pluripotent cell's fate determination

As embryos, all complex organisms are partially made up of pluripotent stem cells, a term for cells that have the capacity to differentiate into any kind of cell: nerve cells, muscle cells, blood cells, skin cells, and the like.

29 Apr 2024

Harnessing immune enhancement to combat drug-resistant tuberculosis

Experts are working on novel immune-enhancing therapies called host-directed therapies to use the body's own immune system to target tuberculosis, with hopes that they could tackle even the drug-resistant forms of the disease.

26 Apr 2024

Study suggests lingering coronavirus in tissues may contribute to long COVID symptoms

Study investigated whether SARS-CoV-2 lingers in tissues after COVID-19 recovery and if it's linked to long COVID symptoms. They found viral RNA in various organs, and its presence correlated with long COVID symptoms.

25 Apr 2024

Scientists identify signaling pathway in liver cells linked to fibrosis

A healthy liver filters all the blood in your body, breaks down toxins and digests fats. It produces collagen to repair damaged cells when the liver is injured.

25 Apr 2024

New research lays foundation for targeted therapies to inhibit NF-κB activation

A new paper by Dana-Farber Cancer Institute scientists lays the foundation for targeted therapies to inhibit activation of nuclear factor kappa B (NF-κB), a transcription factor that plays a role in various autoimmune and inflammatory diseases and cancers.

25 Apr 2024

Synthetic nanomaterial could be an effective tool for treating neurodegenerative diseases

A newly developed nanomaterial that mimics the behavior of proteins could be an effective tool for treating Alzheimer's and other neurodegenerative diseases.

25 Apr 2024

Genetically modified mice reveal key players in immune defense against viruses

Chemokines are signaling proteins that orchestrate the interaction of immune cells against pathogens and tumors.

25 Apr 2024

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

Paclitaxel treatment found to directly promote HBV replication and transcription

Hepatitis B virus (HBV) reactivation is commonly observed in individuals with chronic HBV infection undergoing antineoplastic drug therapy.

24 Apr 2024

Study unveils novel bladder cancer diagnostic model based on key mitochondrial genes

A novel diagnostic model using machine learning (ML).

24 Apr 2024

New tARC-seq method enhances precision in tracking SARS-CoV-2 mutations

A tARC-seq approach to precisely determine SARS-CoV-2 mutation frequency.

24 Apr 2024

Study identifies molecular pathway in liver cancer development

As a malignant disease of the liver cells, hepatocellular carcinoma (HCC) is one of the main causes of cancer-related deaths.

23 Apr 2024

Cells use liquid droplets to regulate signaling pathways, study finds

Healthy cells respond appropriately to changes in their environment. They do this by sensing what's happening outside and relaying a command to the precise biomolecule in the precise domain that can carry out the necessary response.

22 Apr 2024

Breakthrough study reveals role of histone deacetylases in inflammatory bowel disease

In a scientific breakthrough, Mount Sinai researchers have revealed the biological mechanisms by which a family of proteins known as histone deacetylases (HDACs) activate immune system cells linked to inflammatory bowel disease (IBD) and other inflammatory diseases.

22 Apr 2024

Transcription News and Research

Study reveals impact of Mediator protein complex on cell division regulation

Breakthrough study identifies potential treatments for influenza-associated encephalopathy

Researchers identify key molecular alterations from endurance exercise that could combat chronic diseases

Study highlights the role of dynamic DNA structures in memory consolidation

New drug candidate reverses obesity in mice by transforming liver metabolism

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Unlocking the mechanisms of pluripotent cell's fate determination

Harnessing immune enhancement to combat drug-resistant tuberculosis

Study suggests lingering coronavirus in tissues may contribute to long COVID symptoms

Scientists identify signaling pathway in liver cells linked to fibrosis

New research lays foundation for targeted therapies to inhibit NF-κB activation

Synthetic nanomaterial could be an effective tool for treating neurodegenerative diseases

Genetically modified mice reveal key players in immune defense against viruses

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Paclitaxel treatment found to directly promote HBV replication and transcription

Study unveils novel bladder cancer diagnostic model based on key mitochondrial genes

New tARC-seq method enhances precision in tracking SARS-CoV-2 mutations

Study identifies molecular pathway in liver cancer development

Cells use liquid droplets to regulate signaling pathways, study finds

Breakthrough study reveals role of histone deacetylases in inflammatory bowel disease

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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