immunity News and Research

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New influenza vaccine strategies aim to enhance protection with T-cell responses

A recent review highlights the need for innovative influenza vaccines that combine T-cell and antibody responses to enhance protection across multiple strains and seasons.

6 May 2024

Novel vaccine approach targets AML and other blood cancers

Acute myeloid leukemia (AML) is a type of blood cancer that forms in the soft marrow of the bones, typically attacking cells that would otherwise form the key component of the body's immunodefense system, white blood cells.

3 May 2024

NK cells' role in cancer therapy resistance unveiled

Activated T cells that carry a certain marker protein on their surface are controlled by natural killer (NK) cells, another cell type of the immune system.

3 May 2024

Unlocking glioblastoma's immune suppression mechanism

The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma -; a serious and often fatal brain cancer -; suppresses the immune system so that the tumor can grow unimpeded by the body's defenses.

3 May 2024

New vaccine approach shows promise in targeting less variable region of influenza virus

Duke researchers have opened a new avenue in the attack against influenza viruses by creating a vaccine that encourages the immune system to target a portion of the virus surface that is less variable.

2 May 2024

Study reveals molecular changes in 19 organs due to exercise

The health benefits of exercise are well known but new research shows that the body's response to exercise is more complex and far-reaching than previously thought.

2 May 2024

Columbia researchers uncover brain's ability to control inflammation

The brain can direct the immune system to an unexpected degree, capable of detecting, ramping up and tamping down inflammation, shows a new study in mice from researchers at Columbia's Zuckerman Institute.

2 May 2024

Increased emotional sensitivity linked to previous COVID-19 infection, new research suggests

How prior coronavirus disease 2019 (COVID-19) infection, through behavioral immunity markers, impacts socioemotional functioning.

2 May 2024

Machine learning tool can speed the diagnosis of undiagnosed patients with rare immune disorders

Researchers say a machine learning tool can identify many patients with rare, undiagnosed diseases years earlier, potentially improving outcomes and reducing cost and morbidity. The findings, led by researchers at UCLA Health, are described in Science Translational Medicine.

1 May 2024

Gut bacteria and urinary infections linked, offering new angles for treatment

A study in eClinicalMedicine explores the relationship between gut microbiota, urinary tract colonization, and recurrent urinary tract infections (rUTI), suggesting the cross-habitation of uropathogenic E. coli as a significant mechanism in rUTI recurrence.

30 Apr 2024

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Currently, most therapies for allergic diseases require lifelong treatment. Allergic reactions, characterized by ongoing (type 2) inflammation in response to chronic antigen exposure, underlie many chronic diseases in humans, including asthma, atopic dermatitis, ulcerative colitis and more.

30 Apr 2024

Updated vaccine provides strong immune response against previous and emerging SARS-CoV-2 variants

New research using live SARS-CoV-2 virus reveals an updated vaccine provides a strong immune response against previous strains and emerging variants.

29 Apr 2024

Measles and rubella vaccine delivered via microarray patch shows promising results

The phase 1/2 randomized trial compared results from the measles and rubella vaccine delivered by a microarray patch, a small sticking plaster-like device with an array of microscopic projections that painlessly penetrate the skin and deliver the vaccine, or by conventional injection with a needle and syringe.

29 Apr 2024

Study reveals brown fat's built-in mechanism and potential obesity treatment

Brown fat, also known as brown adipose tissue (BAT), is a type of fat in our bodies that's different from the white fat around our belly and thighs that we are more familiar with.

29 Apr 2024

Study rethinks immune system strategies to boost vaccine effectiveness

A recent Cell journal review explores key immunological assumptions to enhance our understanding of vaccine design, autoimmune responses, and immune system pathology, aiming to refine intervention strategies and theoretical frameworks in immunology.

28 Apr 2024

Harnessing immune enhancement to combat drug-resistant tuberculosis

Experts are working on novel immune-enhancing therapies called host-directed therapies to use the body's own immune system to target tuberculosis, with hopes that they could tackle even the drug-resistant forms of the disease.

26 Apr 2024

Leveraging CRISPR/Cas technology to address antimicrobial resistance

In the second new research review on this subject, Assistant Prof. Ibrahim Bitar, Department of Microbiology, Faculty of Medicine and University Hospital in Plzen, Charles University in Prague, Plzen, Czech Republic, will give an overview of the molecular biology of CRISPR technology in explaining how it can used to tackle antimicrobial resistance.

26 Apr 2024

New study offers promising targets for universal influenza B vaccine

In a milestone study led by the Peter Doherty Institute of Infection and Immunity (Doherty Institute), researchers have identified fragments from influenza B viruses that the immune system consistently recognize, offering promising targets for a universal influenza B vaccine

26 Apr 2024

Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

A review in Nature Reviews Nephrology presents the association between immune cells and the development of hypertension, suggesting potential new therapeutic targets to mitigate the disease by managing inflammation.

26 Apr 2024

Study suggests lingering coronavirus in tissues may contribute to long COVID symptoms

Study investigated whether SARS-CoV-2 lingers in tissues after COVID-19 recovery and if it's linked to long COVID symptoms. They found viral RNA in various organs, and its presence correlated with long COVID symptoms.

25 Apr 2024

immunity News and Research

New influenza vaccine strategies aim to enhance protection with T-cell responses

Novel vaccine approach targets AML and other blood cancers

NK cells' role in cancer therapy resistance unveiled

Unlocking glioblastoma's immune suppression mechanism

New vaccine approach shows promise in targeting less variable region of influenza virus

Study reveals molecular changes in 19 organs due to exercise

Columbia researchers uncover brain's ability to control inflammation

Increased emotional sensitivity linked to previous COVID-19 infection, new research suggests

Machine learning tool can speed the diagnosis of undiagnosed patients with rare immune disorders

Gut bacteria and urinary infections linked, offering new angles for treatment

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Updated vaccine provides strong immune response against previous and emerging SARS-CoV-2 variants

Measles and rubella vaccine delivered via microarray patch shows promising results

Study reveals brown fat's built-in mechanism and potential obesity treatment

Study rethinks immune system strategies to boost vaccine effectiveness

Harnessing immune enhancement to combat drug-resistant tuberculosis

Leveraging CRISPR/Cas technology to address antimicrobial resistance

New study offers promising targets for universal influenza B vaccine

Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

Study suggests lingering coronavirus in tissues may contribute to long COVID symptoms

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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