ADVIA 2120i Hematology System with Autoslide to maximize productivity

The ADVIA^® 2120i System with Autoslide, a high-volume hematology analyzer from Siemens Healthineers, optimizes workflow by omitting the bulk of routine manual activities performed to increase efficiency. It offers users the simplicity and flexibility they need for simple integration into the lab while delivering the gold standard in testing methodology for the best results.

• Distinguishes microcytic anemias using advanced reticulocyte and RBC technologies
• Automates hematological process, eliminating the need for expensive stains, massive track-based systems, or reflexive testing
• Delivers gold-standard flow cytometry peroxidase methodology for optimum results
• Enhances the efficacy of expensive platelet transfusions with precise outcomes the first time, even at very low platelet counts
• With Unifluidics^™ Technology, which reduces fluidics, eliminates pinch valves and automates daily cleaning, maintenance is made simpler
• A unique high-volume hematology solution provided by Practical Automation’s ADVIA 2120i System enables the lab to increase productivity without compromising quality

ADVIA^® 2120i Hematology System with Autoslide. Image Credit: Siemens Healthineers

Features and benefits

The ADVIA^® 2120i Hematology System is the only system capable of fully automating the hematology lab without the use of large track-based systems, expensive stains, or reflexive testing. This is the way Siemens Healthineers provide the hematology lab with Practical Automation.

Image Credit: Siemens Healthineers

Practical automation

• Enhance productivity in the bustling laboratory environment
• Without the usage of large track-based systems, expensive stains, or reflexive testing, the ADVIA^® 2120i Hematology System can automate a user’s hematology lab
• This is the way Siemens Healthineers supplies the hematology lab with Practical Automation

Quality results

• Blood cell differentials that are distinctive and in-depth
• Gold-standard Peroxidase technology yields accurate findings on the first pass, eliminating the need for manual slides
• Automated sampling with rapid turnaround time

Enhanced productivity

• Walk-away capability through Practical Automation
• Onboard delta checks minimize manual slide reviews
• Unique reagent TIMEPACS^® minimizes hands-on time
• User-defined auto validation minimizes staff intervention
• Effortless system maintenance is facilitated by robust Unifluidics™ technology, which reduces fluidics

Sensitive and specific RBC morphology

• True RBC differential
• No interference from lipemia
• Completely automated nRBC on the first pass; no reflex is necessary
• Direct measurement of Reticulocytes with quantitative morphology flags
• Unique dual hemoglobin testing offers validation and assurance of results

Unique CHr Methodology

• Accurate measurement of functional iron
• Onboard measurement of functional cellular hemoglobin content
• Provides a rapid means for assessing the erythropoietic response to iron replacement therapy
• Provides the capability to distinguish iron deficiency from other causes of anemia

Automated 2D platelet differentiation

• Measures up to 60 fL and includes large platelets
• Excludes fragments and microcytic RBC
• Distinctive technology for accurate classification
• Measures 2 dimensions in a single pass (size and refractive index), eliminating the need for re-runs

Definitive WBC classification

• First pass accuracy in WBC classification
• Dual technologies provide confirmatory results in a single pass
• Classification of cells using peroxidase and nuclear density shows patterns in cell clustering and scattering that are related to certain leukemia types and other cell abnormalities

Unparalleled CSF results

• Extended parameters onboard
• Automated analysis of manual processes that used to be time-consuming
• Testing capabilities include RBC, WBC, and Differentials
• The unique playback blending feature ensures accuracy in samples with very low cell counts

ADVIA Autoslide Slide Maker Stainer

• Low sample volume required—only 75 µl per slide
• Individual staining wells provide clean stains for each slide
• User-definable reflexive slide making
• Automated reflexive slide making/staining
• Up to 96 high-quality slides per hour

Comprehensive quality control

• Electronic ILQC^® program for peer group comparisons
• Levey-Jennings and Bar M graphs with user-defined views
• Intuitive management of QC data
• Easy, quick scanned entry of all lot information

Reagent management

• Compact packaging with powerful capabilities
• Reagent TIMEPACS provides walk-away assistance and has a 1,800 test capacity
• TIMEPACS supplied in matching configurations deplete concurrently
• Comprehensive reagent logs for workload data and audit trails

Simplified maintenance

• Onboard technology minimizes operator intervention
• Unique Unifluidics Technology simplifies components and eliminates the tubing and pinch valves
• Simplifies operations—reduces fluidics
• Reduces maintenance—automates daily cleaning
• Aspiration probes with clot filters remove clots from the system fluidics

Scalable automation solutions

• Adaptive automation to support the laboratory’s needs
• Practical Automation offers flexible solutions that can be installed on track-based systems or independently
• Reduces productivity loss caused by any automated component getting interrupted
• CentraLink^® Data Management System enables data management and quality control administration from any workstation

A hematological analyzer that removes the majority of commonly performed manual procedures can streamline workflow and increase productivity. The ADVIA 2120i System offers users the simplicity and flexibility they want for simple integration into the lab while delivering the gold standard in testing methodology for optimal results.

The gold standard in differential testing, peroxidase staining, is used by ADVIA technology. The ADVIA Hematology Systems’ primary technique also offers a secondary total white cell count, which serves as an internal QA check to ensure sample integrity.

• A six-parameter differential and unique cytochemical differentiation of myeloid and lymphoid cells provide further clinical data
• For precise and early disease state detection, direct measurements of intracellular hemoglobin offer sensitive and distinctive RBC morphology.
• Minimize the need for manual counts and needless, expensive platelet transfusions by ensuring that platelet counts are accurate and within the clinically important range (excluding microcytic red cells and cell fragments)
• Using CSF and CHr testing capabilities, further segregate and detect disease states without additional labor

With the ADVIA 2120i System, enhancing users’ capabilities is easier than ever. Users can transition from standalone instrumentation to full automation as their productivity demands evolve using integrated and automated solutions from Siemens Healthineers.

Assays

Parameters

Table 1. Source: Siemens Healthineers

Morphology results (User definable)

Table 2. Source: Siemens Healthineers

** Laboratory Use Only
^† CN-free HB method

Technical specifications

Performance specifications

Table 3. Source: Siemens Healthineers

Precision

Table 4. Source: Siemens Healthineers

Test selectivity/throughput

Table 5. Source: Siemens Healthineers

Sample modes/volumes

Table 6. Source: Siemens Healthineers

Weight and dimensions 

Table 7. Source: Siemens Healthineers

Workstation specifications

• Intel Pentium E6500 Dual Core 2.93 GHz
• 350W Desktop/Tower
• 3Gb/s 7200 RPM 16MB Cache Hard Drive
• 1 GB Memory Module
• CD-RW
• 17” Touchscreen Color LCD Monitor
• Full-sized Keyboard (major languages)

Autosampler option

Table 8. Source: Siemens Healthineers

Other specifications

• Onboard analytical and wash reagents (1850 CBC/Diff tests)
• Automated Daily Maintenance—fully programmable