Biochemistry

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Breakthrough discovery could lead to new class of antibiotics

The last time a new class of antibiotics reached the market was nearly three decades ago - but that could soon change, thanks to a discovery by researchers at McMaster University.

26 Mar 2025

INTEGRA Biosciences details the evolution and future of serological pipetting

INTEGRA Biosciences has played a pivotal role in advancing the field of serological pipetting over the last 40 years, and has just created a fascinating article covering the fast-paced history of serological pipet controller development.

25 Mar 2025

Study offers new insights into the harmful effects of sugar-sweetened beverages on human health

Researchers at the Advanced Research Unit on Metabolism, Development & Aging (ARUMDA), in the Tata Institute of Fundamental Research (TIFR, Mumbai and TIFR Hyderabad), have unveiled a comprehensive understanding of the harmful effects of sugar-sweetened beverages (SSBs) on human health, using a preclinical mouse model that closely mimics human consumption patterns.

21 Mar 2025

Anti-HIV active diterpenoids identified in Daphne pseudomezereum

A research group led by Professor Wei Li from the Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Toho University, in collaboration with the Duke University Medical Center in the United States, has discovered for the first time that Daphne pseudomezereum (commonly known as Onishibari) contains a substance inhibiting replication of human immunodeficiency virus (HIV).

21 Mar 2025

Biomanufacturing platform offers a sustainable alternative to synthesizing peptide-based pharmaceuticals

To tackle the inequity in medication access, a societal issue especially in developing nations, a team of undergraduate student-researchers at the University of Ottawa has developed a new biomanufacturing platform called Phytogene.

18 Mar 2025

Frequently asked questions about BioAFM

Do you have a question about BioAFM? This article will tell you everything you need to know.

From Bruker BioAFM 17 Mar 2025

Optimized fermentation process unlocks anti-aging potential of tapuy lees

Filipino researchers have found a way to optimize the traditional procedure for making Philippine rice wine or "tapuy" to produce a potential superfood rich in anti-aging compounds and antioxidants.

14 Mar 2025

Researchers develop new compound to treat alopecia areata

A research group, led by Dr. Pavel Majer from IOCB Prague, in collaboration with the laboratories of Barbara Slusher and Louis Garza at Johns Hopkins University, have developed a compound that could potentially treat the autoimmune disorder alopecia areata, which causes hair loss leading to the formation of bald patches.

13 Mar 2025

Shift Biosciences announces key appointments to advance rejuvenation therapeutics pipeline

Shift Biosciences, a biotech company using an AI powered virtual cell to fight age-related diseases, today announced the appointments of Jill Reckless, Ph.D, as Translation Advisor and Laurence Reid, Ph.D., as Non-Executive Director. In these roles, Jill and Laurence will guide Shift in building a robust product translation and business development strategy respectively, enabling the Company to capitalize on early momentum and progress its pipeline of novel rejuvenation therapeutics towards clinical development.

12 Mar 2025

Researchers identify unique enzyme that targets prebiotic glycans

Carbohydrate chains, or glycans, are complex sugar-like compounds that play important roles in various biological processes and structures in our bodies.

6 Mar 2025

Naturally occurring molecule suppresses appetite and promotes weight loss

A naturally occurring molecule identified by Stanford Medicine researchers appears similar to semaglutide - also known as Ozempic - in suppressing appetite and reducing body weight.

6 Mar 2025

Global study sheds light on differences in medicine taste sensitivity

Many medicines taste so bitter that some people avoid taking them. To help with the bad taste, flavors and sweeteners are added to modify the taste and make it more acceptable.

4 Mar 2025

Study uncovers how glucose excreted in the gut converts into beneficial fatty acids

Gut microbes that were thought to feed exclusively on dietary fiber also get fed sugar from our guts, from which they produce short-chain fatty acids that are crucial to many body functions.

4 Mar 2025

New chemical reaction enables precise functionalization of peptides and proteins

Pharmaceutical scientists at the National University of Singapore (NUS) have developed a novel chemical reaction that enables the precise functionalization of peptides and proteins.

28 Feb 2025

Breakthrough method opens door to fluorinated oxetane drug molecules

Researchers from the National University of Singapore (NUS) have pioneered a new catalytic transformation that converts epoxides into fluorinated oxetanes, a coveted but difficult-to-make class of drug molecules that escaped synthetic preparation for years.

22 Feb 2025

New human antibody shows promise for Ebola virus treatment

New research led by scientists at La Jolla Institute for Immunology (LJI) reveals the workings of a human antibody called mAb 3A6, which may prove to be an important component for Ebola virus therapeutics.

21 Feb 2025

Zinc-carrying proteins may activate PPIs in the absence of gastric acid

Acid reducing medicines from the group of proton pump inhibitors (PPIs) are best-selling drugs that prevent and alleviate stomach problems.

21 Feb 2025

Plant immune responses may offer insights into human brain diseases

A groundbreaking study led by a team of researchers at the University of Kentucky's Martin-Gatton College of Agriculture, Food and Environment has revealed a surprising biochemical connection between plant immune responses and human neurological health.

19 Feb 2025

Harvard researchers map 70,000 synaptic connections in rat brain

Harvard researchers have mapped and catalogued more than 70,000 synaptic connections from about 2,000 rat neurons, using a silicon chip capable of recording small yet telltale synaptic signals from a large number of neurons.

14 Feb 2025

Duke engineers develop synthetic approach to boost bacterial protein synthesis

Biomedical engineers at Duke University have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, such as antibiotics.

11 Feb 2025