Biochemistry

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Duke engineers develop synthetic approach to boost bacterial protein synthesis

Biomedical engineers at Duke University have demonstrated a new synthetic approach that turbocharges bacteria into producing more of a specific protein, even proteins that would normally destroy them, such as antibiotics.

11 Feb 2025

Innovative approach to synthesizing functional molecules with triple click chemistry

Middle molecules with a molecular weight of more than 1,000 are difficult to synthesize due to multiple steps and time-consuming nature, demanding the development of a new approach that can overcome these disadvantages.

11 Feb 2025

Gut bacteria influence brain protein modifications via glycosylation

Our guts are home to trillions of bacteria, and research over the last few decades has established how essential they are to our physiology – in health and disease.

10 Feb 2025

Collagen's structural diversity may be greater than previously believed, study suggests

Collagen, the body's most abundant protein, has long been viewed as a predictable structural component of tissues.

7 Feb 2025

Study reveals differences in allosteric behavior of cAMP receptor proteins in M. tuberculosis

A new study, "Identifying Allosteric Hotspots in Mycobacterium tuberculosis cAMP Receptor Protein" published in Biochemistry, provides key insights into how bacterial cAMP receptor proteins (CRPs) respond differently to the ubiquitous signaling molecule, cyclic AMP (cAMP).

7 Feb 2025

Gyros Protein Technologies introduces Gyrolab HEK293 HCP Type SN and Type CL Kit Reagents to support biotherapeutic development

Gyros Protein Technologies AB, a pioneer in automated nanoliter-scale immunoassays and leading provider of peptide synthesizers, today announced the introduction of its Gyrolab® HEK293 HCP Type SN Kit Reagents and Gyrolab HEK293 HCP Type CL Kit Reagents.

6 Feb 2025

New method uses DNA sequencing for precise metabolite measurement

Researchers at the University of Toronto have invented a new method that uses DNA sequencing to measure metabolites. This enables rapid and precise analysis of biological compounds, such as sugars, vitamins, hormones and the hundreds of other metabolites that are critical for health.

4 Feb 2025

Nanoflower-coated bandages could improve wound care and fight infections

A carnation-like nanostructure could someday be used in bandages to promote wound healing.

31 Jan 2025

New light-controlled tools offer real-time protein control in living cells

A research group at Umeå University has developed new advanced light-controlled tools that enable precise control of proteins in real time in living cells.

30 Jan 2025

Genetic predisposition plays a role in how coffee tastes bitter to some more than others

Why does coffee taste more bitter to some people than it does to others? Researchers at the Leibniz Institute for Food Systems Biology at the Technical University of Munich have now come closer to answering this question.

29 Jan 2025

Trilobio introduces whole-laboratory automation platform at SLAS2025

Trilobio, developer of whole lab automation solutions for advancing biology research, today introduced the first version of its comprehensive robotics, lab equipment and software platform at the Society for Laboratory Automation and Screening conference, SLAS2025, alongside pilot customer data, demonstrating the platform's abilities in advancing research workflows.

From Trilobio 28 Jan 2025

Chickpea germination offers insights into protein breakdown and nutrients

It's well known that sprouting seeds increases their nutritional value. Researchers led by Professor Denis Shields from University College Dublin in partnership with the health food company, The Happy Pear have uncovered some surprising facts about how the sprouting process varies over time and strain of seed.

28 Jan 2025

Research could lead to better medicines and new tools in synthetic biology

Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions. Their environments-water, lipid membranes, or other condensed phases-are critical to their function, shaping their structure and interactions.

24 Jan 2025

Enhanced biosensing technology detects molecules at lower concentrations

An unplugged electric instrument may function, but it sounds much better when it is connected to an amplifier.

13 Jan 2025

Breakthrough in chemical synthesis expands possibilities for ketones and esters

Scientists have long considered ketones (a fundamental chemical class) and esters (molecules formed when an acid reacts with an alcohol) to be locked treasure chests of possibilities.

10 Jan 2025

Simple green synthesis of silver nanoparticles from goji berries

As the search for sustainability permeates all fields, researchers are turning to a unique organic source for creating antibacterial silver nanoparticles (Ag-NPs) – the humble goji berry.

9 Jan 2025

Unraveling the molecular mechanisms of disease-causing mutations

Most mutations which cause disease by swapping one amino acid out for another do so by making the protein less stable, according to a massive study of human protein variants published today in the journal Nature. Unstable proteins are more likely to misfold and degrade, causing them to stop working or accumulate in harmful amounts inside cells.

9 Jan 2025