Biochemistry

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Diets high in fat and protein exacerbate C. diff infections in mice

Popular diets low in carbs and high in fat and protein might be good for the waistline, but a new UNLV study shows that just the opposite may help to alleviate the hospital-acquired infection Clostridioides difficile.

12 Feb 2020

Researchers discover antibiotics with unique approach to attacking bacteria

A new group of antibiotics with a unique approach to attacking bacteria has been discovered, making it a promising clinical candidate in the fight against antimicrobial resistance.

12 Feb 2020

New approach for organic synthesis may apply to drug discovery

After helping develop a new approach for organic synthesis -- carbon-hydrogen functionalization -- scientists at Emory University are now showing how this approach may apply to drug discovery

12 Feb 2020

New therapeutic compounds could fight against brain-eating amoebae

Brain-eating amoebae can cause particularly harmful forms of encephalitis, and more than 95% of people who develop these rare but devastating infections die.

12 Feb 2020

Natural product from a fungus could shed light on cellular interactions prominent in cancer

A fungus that attacks almond and peach trees may be key to identifying new drug targets for cancer therapy.

12 Feb 2020

Vapers exhibit similar chemical changes in their genome as smokers

Biologically important changes in DNA seen in smokers are also being found in people who vape, according to a new study published in the journal Epigenetics.

12 Feb 2020

Study explores how some mammals postpone development of their embryos

How do some mammals postpone the development of their embryos to await better conditions for having offspring? A recent study at the UW Medicine Institute for Stem Cell and Regenerative Medicine explored this reproductive enigma, which can occur in more than 130 species of mammals as well as in some marsupials.

10 Feb 2020

New hydrogenation process could lead to safe hydrogen gas

Safe and environmentally-friendly hydrogen gas on demand could be on the horizon following a new "hydrogenation" chemical process in development at The City College of New York. Led by Mahesh K. Lakshman, the research uniquely bypasses the need for an external source of hydrogen gas to accomplish a wide range of hydrogenations.

10 Feb 2020

CSU researchers uncover new information on replication of viruses

An interdisciplinary team of researchers at Colorado State University has used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate.

9 Feb 2020

Researchers identify involvement of certain cortical areas in the loss of control over food intake

Researchers at UPF, in collaboration with researchers from the University of Mainz (Germany), the Center for Genomic Regulation, Instituto Cajal, Johannes Gutenberg University (Germany), the Autonomous University Barcelona and Hospital del Mar have identified for the first time the involvement of certain cortical areas in the brain in the loss of control over food intake.

9 Feb 2020

New strategy uses iPSCs to regulate immune reaction to transplanted tissues

Scientists suggest a new strategy that uses induced pluripotent stem cells (iPSCs) to regulate immune reaction to transplanted tissues.

9 Feb 2020

Collaborative research uncovers underlying rules that, when broken, contribute to ALS

Clumps of proteins inside cells are a common thread in many neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) or Lou Gehrig's disease.

7 Feb 2020

Experimental fingerprint test can accurately identify traces of cocaine on human skin

An experimental fingerprint detection approach can identify traces of cocaine on human skin, even after someone has washed their hands - and the test is also smart enough to tell whether an individual has actually consumed the class A drug, or simply handled it.

6 Feb 2020

Targeting the microenvironment of cancer cells to inhibit tumor growth

The recognition of bacterial infections or foreign substances is mediated and controlled by the human immune system. This innate and adaptive immune system comprises the most important metabolic and cellulare processes to fight against infections and other diseases.

5 Feb 2020

UH professor examines life cycle of drug-resistant persister cells in recurrent infections

A University of Houston engineering professor is examining the life cycle of stubborn, drug-resistant persister cells in recurrent infections to find a way to destroy them.

4 Feb 2020

Scientists track down a potential target for new sleeping sickness drugs

Using ultra-bright X-ray flashes, a team of researchers has tracked down a potential target for new drugs against sleeping sickness: The scientists have decoded the detailed spatial structure of a vital enzyme of the pathogen, the parasite Trypanosoma brucei.

30 Jan 2020