Biochemistry

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New technique detects, measures, analyzes unevenly charged biomolecules

In clinical diagnostics, it is critical to monitor biomolecules in a simple, rapid and sensitive way. Clinicians most often monitor antibodies because these small proteins attach to antigens, or foreign substances, we face every day.

17 Aug 2018

Researchers describe link between poor oocyte development and oxidative stress in obese mice

Excessive body fat is associated with negative effects on female fertility and pregnancy. In mice, maternal obesity impairs proper development of egg precursor cells called oocytes.

17 Aug 2018

Discovery may help broaden the scope of defenses against HPV

Yale Cancer Center scientists have filled in a key gap in understanding the unusual route by which the Human papillomavirus infects cells.

16 Aug 2018

Researchers move closer to finding potential soft spot in drug-resistant tuberculosis

Antibiotic-resistant tuberculosis is a public health threat. TB and other bacteria become resistant to antibiotics by evolving genetic changes over time, which they can do quite quickly because bacterial lifecycles are short.

15 Aug 2018

Study provides insight into link between sleep apnea and lipid metabolism

Obstructive sleep apnea is a clinical disorder characterized by repeated partial or complete blockage of the airway during sleep.

15 Aug 2018

Scientists define key binding characteristics of protein associated with heart disease and breast cancer

Galectins attach to other proteins via the carbohydrates on their surfaces (sugar-binding proteins). As such they impact on a range of processes in the cell associated with a number of diseases, including heart disease and breast cancer – the most common cancer in women worldwide, with 1.7 million new cases diagnosed in 2012 alone.

10 Aug 2018

Researchers develop technology to create hybrid catalyst from rhodium and organic catalysts

A group of Japanese researchers has developed a technology to create a hybrid catalyst from simple-structured, commercially available rhodium and organic catalysts, which reduces chemical waste and produces molecules with high selectivity of an enantiomer, a pair of molecular structures that are non-superimposable mirror images of each other.

10 Aug 2018

Researchers describe new class of potent inhibitors against amyloid plaques

Effective therapeutics to counteract the formation of amyloid plaques in Alzheimer's disease and type 2 diabetes are not yet available.

9 Aug 2018

Study: HDAC1 enzyme modifies molecular motor that drives neuron death

A biochemistry instructor curious about an enzyme discovered in the damaged neurons of people with multiple sclerosis made a leap toward a potential cure for countless neurodegenerative ills.

7 Aug 2018

Next-generation metabolomics may pave way for creating new antidepressants

Depression is one of the most common diseases that affects at least 4.4% of the world population since 2015. Current antidepressants are limited by their undesirable side effects and slow onset.

7 Aug 2018

Research uncovers new approach for expanding stem cells from umbilical cord blood

Researchers from the Stowers Institute for Medical Research and collaborators have identified a way to expand blood-forming, adult stem cells from human umbilical cord blood.

3 Aug 2018

Researchers shed new light on how bacteria sense nutrients in their environment

University of Leicester researchers have shed new light on how bacteria sense nutrients in their environment - which could provide important knowledge in the development of drugs and antibiotics to combat a range of diseases including tuberculosis.

3 Aug 2018

New study uses metabolomics to compare lipid profiles of infant formulas and human milk

Metabolomics is the latest omics systems science technology with emerging applications towards psychiatry, personalized medicine, and most recently, precision nutrition research.

3 Aug 2018

Placenta barrier-on-a-chip could help explain why babies are born prematurely

More than one in 10 babies worldwide are born prematurely, according to the World Health Organization. Now scientists report in ACS Biomaterials Science & Engineering that they have developed an organ-on-a-chip that could help explain why.

1 Aug 2018

Pungent compound contained in ginger ensures fresh breath

The pungent compound 6-gingerol, a constituent of ginger, stimulates an enzyme contained in saliva - an enzyme which breaks down foul-smelling substances.

30 Jul 2018

Fucose-based food supplement could be used to stop the spread of norovirus in children's hospitals

Norovirus is the most common cause of gastroenteritis worldwide; it causes tens hundreds of thousands of deaths each year and is particularly risky for children under 3 years old.

27 Jul 2018

Researchers discover new protein that controls level of inflammation-inducing molecule

One of the major therapeutic targets for inflammatory diseases is the inflammation-inducing molecule TNF. However, excess levels of TNF cause side effects and can lead to diseases.

27 Jul 2018

Nucleic acid nanoparticles found to have varying immune responses

An extensive experiment testing the immune effects of a broad group of lab-designed nucleic acid nanoparticles did not find a strong, uniform immune response, as had been predicted.

27 Jul 2018

Researchers develop artificial enzymes that drive reactions on living cells

Nature has evolved thousands of enzymes to facilitate the many chemical reactions that take place inside organisms to sustain life.

26 Jul 2018

Researchers find that IgM antibody could protect against HIV-1

A team of scientists from Texas Biomedical Research Institute have homed in on an antibody that could protect against infection with HIV-1.

24 Jul 2018

Biochemistry

New technique detects, measures, analyzes unevenly charged biomolecules

Researchers describe link between poor oocyte development and oxidative stress in obese mice

Discovery may help broaden the scope of defenses against HPV

Researchers move closer to finding potential soft spot in drug-resistant tuberculosis

Study provides insight into link between sleep apnea and lipid metabolism

Scientists define key binding characteristics of protein associated with heart disease and breast cancer

Researchers develop technology to create hybrid catalyst from rhodium and organic catalysts

Researchers describe new class of potent inhibitors against amyloid plaques

Study: HDAC1 enzyme modifies molecular motor that drives neuron death

Next-generation metabolomics may pave way for creating new antidepressants

Research uncovers new approach for expanding stem cells from umbilical cord blood

Researchers shed new light on how bacteria sense nutrients in their environment

New study uses metabolomics to compare lipid profiles of infant formulas and human milk

Placenta barrier-on-a-chip could help explain why babies are born prematurely

Pungent compound contained in ginger ensures fresh breath

Fucose-based food supplement could be used to stop the spread of norovirus in children's hospitals

Researchers discover new protein that controls level of inflammation-inducing molecule

Nucleic acid nanoparticles found to have varying immune responses

Researchers develop artificial enzymes that drive reactions on living cells

Researchers find that IgM antibody could protect against HIV-1

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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