Biochemistry

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Careful pipetting reduces the stress on cells in culture

Cell viability, defined as the proportion of live cells in a sample, is a fundamental consideration in all cell culture techniques.

From INTEGRA Biosciences 21 Sep 2021

Researchers uncover a molecular mechanism to inhibit aggravation of colitis

The intestinal microbial ecosystem includes diverse species of bacteria. These bacteria can produce bioactive metabolites that directly affect the host's immune system.

21 Sep 2021

Researchers take major step forward in the development of microbial fuel cells

A UCLA-led team of engineers and chemists has taken a major step forward in the development of microbial fuel cells -; a technology that utilizes natural bacteria to extract electrons from organic matter in wastewater to generate electrical currents.

17 Sep 2021

Research could help design peptides to halt antibiotic-resistant bacteria

Peptides could be primed to solve the knotty problem of antibiotic resistance among humans. Rice University scientists believe they can help.

17 Sep 2021

New review highlights several opportunities for improving ginsenoside production

Ginseng, a widely popular superfood, has long been used in traditional medicine. The health benefits of ginseng are largely attributed to compounds called ginsenosides, which are present in the roots, stems, and leaves of the plant. Ginsenosides are known to prevent inflammation, diabetes, and cancer, and can also help control blood cholesterol levels and reduce aging.

16 Sep 2021

Researchers aim to develop edible plant-based mRNA vaccines

The future of vaccines may look more like eating a salad than getting a shot in the arm. UC Riverside scientists are studying whether they can turn edible plants like lettuce into mRNA vaccine factories.

16 Sep 2021

New study reveals chemical steps in an important cellular modification process

The chemical steps in an important cellular modification process that adds a chemical tag to some RNAs have been revealed in a new study. Interfering with this process in humans can lead to neuronal diseases, diabetes, and cancers.

16 Sep 2021

Study pinpoints a potential pathway for treating epileptic seizures in patients with autism

Autism affects about 2% of children in the United States, and about 30% of these children have seizures. Recent large-scale genetic studies revealed that genetic variants in a sodium channel, called voltage-gated sodium channel Nav1.2, is a leading cause of autism.

15 Sep 2021

Researchers focus on improving biomaterials used for bone and tissue repair

Bone injuries in the face and skull-;known as craniomaxillofacial defects-;can be caused by sports injuries, vehicle accidents, or battlefield injuries.

14 Sep 2021

New slow-release system mimics nature to provide long-lasting local anesthesia

Site 1 sodium channel blockers such as tetrodotoxin and saxitoxin are small-molecule drugs with powerful local anesthetic properties.

14 Sep 2021

Researchers explore whether cocoa supplementation can reduce aging

Whether consuming cocoa, known to be packed with powerful antioxidants that protect our cells from damage, helps us age better, is a question scientists want to definitively answer.

14 Sep 2021

Synthetic molecular code shows promise towards improving immunotherapy response of cancer patients

A synthetic molecular code shows promise towards improving the response of some cancer patients to immunotherapy treatments.

14 Sep 2021

Researchers use amphibian foam to deliver drugs for the first time

Amphibian foam has been used in drug delivery for the first time by researchers, which could help to combat the rise of antimicrobial resistance.

9 Sep 2021

Study finds accumulation of common therapeutic drugs by gut bacteria

Common medications can accumulate in gut bacteria, a new study has found, altering bacterial function and potentially reducing the effectiveness of the drug.

8 Sep 2021

Scientists model the process of capsid disassembly in hepatitis B virus at atomic level

With up to 2.4 million U.S. cases and over 250 million chronic cases globally, hepatitis B infection persists despite the availability of a vaccine.

8 Sep 2021

Interorgan network plays an essential role in maternal antibody transfer through breastfeeding

Breastfeeding offers an array of benefits for mothers and newborns. Maternal antibodies are transferred via breastfeeding, protecting the gastrointestinal tracts of babies from several pathogen-caused infections.

8 Sep 2021

Researchers find potential new target for treating systemic inflammation in obesity

A study led by researchers at the University of Chicago and Indiana University has determined that a protein called elF5A is necessary for driving inflammation in macrophage cells in obesity.

7 Sep 2021

Newly identified mechanism can accelerate the development of STING-activating drugs using imaging

A new study from scientists at the UCLA Jonsson Comprehensive Cancer Center found that emerging drugs that activate the protein STING, a well-established regulator of immune cell activation, substantially alter the activity of metabolic pathways responsible for generating the nucleotide building blocks for DNA.

7 Sep 2021

Study could help improve design, fabrication, and use of nanofiber face masks

Since its outbreak, the COVID-19 virus has infected more than 207.7 million people worldwide and has claimed more than 4.3 million lives, according to the World Health Organization coronavirus dashboard as of Aug. 17.

7 Sep 2021

Scientists identify a critical checkpoint in transcription elongation

Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template, according to findings published in Molecular Cell.

4 Sep 2021