Biochemistry

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Researchers investigate how intestinal bacteria distribute metabolic products in membrane vesicles

Bacteria in the intestine pack a wide spectrum of their biomolecules into small capsules. These are transported via the bloodstream to various organs in the body and even absorbed and processed by nerve cells in the brain.

9 Nov 2021

BioIVT to highlight the use of SCHH model to investigate drug-drug interaction of bempedoic acid

BioIVT, a leading provider of research models and services for drug and diagnostic development, is hosting a webinar in which researchers will discuss how they used a sandwich-cultured human hepatocyte (SCHH) model to investigate the drug-drug interaction (DDI) potential of bempedoic acid, a drug that was recently approved to treat hypercholesterolemia.

9 Nov 2021

Research could lead to new methods for tracking COVID-19

The last issue of Wiley's Research Headlines highlighted part one of a study in Environmental Toxicology and Chemistry that involved analysis of sludge from a wastewater treatment plant in Connecticut, and revealed trends in levels of chemicals such as pharmaceuticals and drugs during the first wave of the COVID-19 pandemic.

3 Nov 2021

Researchers identify a single protein that balances sugar and fat metabolism in the liver

Keeping everything running smoothly inside the human body is a tricky business that involves a multitude of checks and balances to make sure that an exquisite equilibrium is maintained.

2 Nov 2021

Drug-like molecule can counteract the effects of mutated epigenetic regulators that drive cancers

A decade ago, genome sequencing revealed a big surprise: about 50 percent of human cancers are linked to mutations in what are known as epigenetic regulators, which control the activity of genes.

29 Oct 2021

Novel ribosome-targeting antibiotic overcomes bacterial multidrug resistance

A new study published in Nature reports on a new antibiotic that binds to the ribosome of bacterial cells and stops drug-resistant pathogens from making mice sick.

28 Oct 2021

New system created for targeted delivery of anti-cancer drugs

RUDN University and Shahid Beheshti University (SBU) chemist together with colleagues from Iran created a system for targeted delivery of anti-cancer drugs.

27 Oct 2021

Modulating glycogen metabolism in fat cells may offer new approaches for weight loss

Humans carry around with them, often abundantly so, at least two kinds of fat tissue: white and brown. White fat cells are essentially inert containers for energy stored in the form of a single large, oily droplet.

27 Oct 2021

Researchers use a mathematical model to better understand the immune response to vaccines

When it comes to the design of a novel vaccine against viral infection, vaccine developers have to make several major decisions. One of them is the choice of what type of immune response they wish to induce.

27 Oct 2021

McMaster-Hamburg collaboration discovers promising new antimalarial compound

A study out of the Michael G. DeGroote Institute for Infectious Disease Research at McMaster University has resulted in the discovery of a promising new antimalarial compound.

27 Oct 2021

Discovery of carbon-carbon bond-forming reaction opens the door to more stable drugs

Medicines come from chemical reactions, and better chemical reactions lead to better medicines.

27 Oct 2021

Consecutive irradiation with two lasers helps adult stem cells to transform faster

Stem cell therapy needs a lot of human cells, of a specific type. Shining a near-infrared laser on adult stem cells derived from human body fat, makes the stem cells replicate 54% faster.

26 Oct 2021

New computer-aided data tool could improve treatment for many diseases

Scientists from Queen's University Belfast have developed a computer-aided data tool that could improve treatment for a range of illnesses.

26 Oct 2021

UQ-developed oral vaccine marks a leap forward in the battle against hookworm infections

There's been a significant breakthrough in the development of a vaccine to prevent hookworm infection – a parasite which causes serious disease in tens of millions of people globally.

26 Oct 2021

Researchers develop ferritin-based nanomedicine for targeted delivery of leukemia therapy

Researchers from the Institute of Process Engineering\ of the Chinese Academy of Sciences, Peking University and Zhujiang Hospital of Southern Medical University have developed a ferritin (Fn)-based nanomedicine for targeted delivery of arsenic (As) and efficient therapy against diverse leukemia types.

25 Oct 2021

UCI study demonstrates the efficiency of wastewater-based epidemiology to monitor SARS-CoV-2

Alternative viral detection methods have been critical in the fight against COVID-19, helping to reduce the burden on our healthcare system.

22 Oct 2021

Enzymes with diverse functions can be rationally harnessed to offer traceless protein synthesis

A multi-enzyme platform is developed for sequence-unconstrained traceless protein synthesis and modification with either synthetic peptides or recombinant proteins, according to a new study out of Chinese Academy of Sciences and Fresenius Kabi.

22 Oct 2021

Adding RNA-inspired ‘breaking points’ to polymer for preventing plastic pollution

Once plastic products are used and discarded, they can linger in oceans, collecting in large "garbage patches" and harming sea life. One potential solution, a biodegradable polymer called polylactide (PLA), has so far not fully lived up to its promise, showing little sign of breakdown once in seawater.

20 Oct 2021

Study offers clues to why calorie-restricted diet may slow tumor growth

In recent years, there has been some evidence that dietary interventions can help to slow the growth of tumors.

20 Oct 2021

New approach to predict the enzyme activity using AI

Without enzymes, an organism would not be able to survive. It is these biocatalysts that facilitate a whole range of chemical reactions, producing the building blocks of the cells. Enzymes are also used widely in biotechnology and in our households, where they are used in detergents, for example.

20 Oct 2021

Biochemistry

Researchers investigate how intestinal bacteria distribute metabolic products in membrane vesicles

BioIVT to highlight the use of SCHH model to investigate drug-drug interaction of bempedoic acid

Research could lead to new methods for tracking COVID-19

Researchers identify a single protein that balances sugar and fat metabolism in the liver

Drug-like molecule can counteract the effects of mutated epigenetic regulators that drive cancers

Novel ribosome-targeting antibiotic overcomes bacterial multidrug resistance

New system created for targeted delivery of anti-cancer drugs

Modulating glycogen metabolism in fat cells may offer new approaches for weight loss

Researchers use a mathematical model to better understand the immune response to vaccines

McMaster-Hamburg collaboration discovers promising new antimalarial compound

Discovery of carbon-carbon bond-forming reaction opens the door to more stable drugs

Consecutive irradiation with two lasers helps adult stem cells to transform faster

New computer-aided data tool could improve treatment for many diseases

UQ-developed oral vaccine marks a leap forward in the battle against hookworm infections

Researchers develop ferritin-based nanomedicine for targeted delivery of leukemia therapy

UCI study demonstrates the efficiency of wastewater-based epidemiology to monitor SARS-CoV-2

Enzymes with diverse functions can be rationally harnessed to offer traceless protein synthesis

Adding RNA-inspired ‘breaking points’ to polymer for preventing plastic pollution

Study offers clues to why calorie-restricted diet may slow tumor growth

New approach to predict the enzyme activity using AI

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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