Cell Biology

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New tool can help researchers split and reassemble proteins

Researchers have developed a computational tool that makes it possible to split proteins and then restore them to functionality.

2 Oct 2018

Newly discovered protein shown to cause amyloid-beta plaques in Alzheimer's

Scientists have discovered that a potassium channel called KCNB1 can trigger the formation of amyloid-beta plaques seen in Alzheimer's disease.

2 Oct 2018

Immune protein 'flutters' like a butterfly in search of viruses, finds study

Researchers at Rutgers Robert Wood Johnson Medical School have identified an important step in the process that allows our bodies to fight viruses.

2 Oct 2018

New, more efficient method for generating brain stem cells in the lab

In two newly published papers, a scientific team at Case Western Reserve University School of Medicine reports on the discovery and implementation of a new, more efficient method for generating an important brain stem cell in the laboratory.

1 Oct 2018

TEAD1 protein appears to be important regulator of tumor migration in glioblastoma

A specific protein called TEAD1 is an important regulator of tumor migration in glioblastoma, the most common brain tumor in adults, and deactivating this protein may stop tumor cells from migrating away from the main tumor mass, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 1 in the journal Nature Communications.

1 Oct 2018

Researchers deplete key protein for DNA replication using protein degradation system

Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently developed conditional protein degradation system.

29 Sep 2018

Scientists investigate effect of flu-causing virus on three lung-derived cell lines

Perhaps inspired by the annual 3 to 5 million cases of severe influenza worldwide, the Guinness World Record organization is advertising for individuals or organizations to attempt a record for the most people getting a flu awareness lesson at once.

29 Sep 2018

Researchers create photoswitchable fluorescent proteins with optical properties

Researchers developed fluorescent proteins that can be controlled by orange and green light. These proteins will help to study processes in living cells. The work was supported by Russian Science Foundation grant, and the results were published in Nature Methods.

28 Sep 2018

Researchers start to understand how to make lab-grown heart cells mature

Scientists at Boston Children’s Hospital have made important steps towards overcoming the hurdles that stand in the way of getting heart muscle to regenerate following engraftment with lab-made heart muscle cells (cardiomyocytes).

28 Sep 2018

Research reveals how critical oocyte quality control process works

Females are born with a finite number of eggs that are steadily depleted throughout their lifetime. This reserve of eggs is selected from a much larger pool of millions of precursor cells, or oocytes, that form during fetal life.

28 Sep 2018

Researchers find a novel way to tease out key factor involved in heart muscle maturation

Scientists around the world have been trying to replace damaged heart tissue using lab-made heart-muscle cells (cardiomyocytes), either injecting them into the heart or applying patches laced with the cells. But results to date have been underwhelming.

28 Sep 2018

Normal skin is more resilient to cancer than previously thought

Normal skin contains a patchwork of mutated cells, yet very few go on to eventually form cancer and scientists have now uncovered the reason why. Researchers at the Wellcome Sanger Institute and MRC Cancer Unit, University of Cambridge genetically engineered mice to show that mutant cells in skin tissue compete with each other, with only the fittest surviving.

27 Sep 2018

Professor Magdalena Götz wins 2018 IRP Schellenberg Research Prize

Every two years, the International Foundation for Research in Paraplegia awards the IRP Schellenberg Research Prize endowed with a prize money of 100,000 CHF.

27 Sep 2018

Axol's Human iPSC-derived Microglia for neuroimmunology research

Our Human iPSC-derived Microglia are suitable for a variety of applications including in vitro disease models, phenotypic screening and immunology studies.

From Axol Bioscience Ltd 27 Sep 2018

Not all P53 mutations cause skin cancer

Today, scientists have explained for the first time why not all UV-induced, P53 mutated skin cells develop into cancer.

27 Sep 2018

New cell-based profiling service from RBC and Promega

A new cell-based profiling service for drug discovery has been announced by RBC and Promega Corporation.

From Promega Corporation 27 Sep 2018

Minicells play key function in self-preservation of bacteria, finds study

Scientists have known for decades that certain bacteria produce small spherical versions of themselves. Although they lack basic materials to reproduce or function like normal cells, recent interest in such "minicells" has spiked due to their proficiency as nano-sized delivery tools for drugs and vaccines to targeted cells and tissues.

27 Sep 2018

Researchers uncover molecular underpinnings of liver regeneration

In Greek mythology, Zeus punishes the trickster Prometheus by chaining him to a rock and sending an eagle to eat a portion of his liver every day, in perpetuity. It was the right organ to target - the liver has the ability to regenerate itself, though not overnight nor for eternity.

27 Sep 2018

Drosophila study shows chromosomal instability promotes invasive behavior in human tumors

Metastatic tumors are characterized by a high degree of chromosomal instability--that is to say a constant change in the number and structure of chromosomes they hold. In spite of this observation, it is unknown whether chromosomal instability contributes to the metastatic process.

26 Sep 2018