Cell Biology

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Not all P53 mutations cause skin cancer

Today, scientists have explained for the first time why not all UV-induced, P53 mutated skin cells develop into cancer.

27 Sep 2018

New cell-based profiling service from RBC and Promega

A new cell-based profiling service for drug discovery has been announced by RBC and Promega Corporation.

From Promega Corporation 27 Sep 2018

Minicells play key function in self-preservation of bacteria, finds study

Scientists have known for decades that certain bacteria produce small spherical versions of themselves. Although they lack basic materials to reproduce or function like normal cells, recent interest in such "minicells" has spiked due to their proficiency as nano-sized delivery tools for drugs and vaccines to targeted cells and tissues.

27 Sep 2018

Researchers uncover molecular underpinnings of liver regeneration

In Greek mythology, Zeus punishes the trickster Prometheus by chaining him to a rock and sending an eagle to eat a portion of his liver every day, in perpetuity. It was the right organ to target - the liver has the ability to regenerate itself, though not overnight nor for eternity.

27 Sep 2018

Drosophila study shows chromosomal instability promotes invasive behavior in human tumors

Metastatic tumors are characterized by a high degree of chromosomal instability--that is to say a constant change in the number and structure of chromosomes they hold. In spite of this observation, it is unknown whether chromosomal instability contributes to the metastatic process.

26 Sep 2018

Researchers to build 3D map of human cells and tissues

Researchers at CMU are working with the NIH to build 3D map of human cells and tissues as part of the Human BioMolecular Atlas Program (HuBMAP).

26 Sep 2018

Biological 'switch' influences whether immature blood cells differentiate into red or white blood cells

Japanese scientists have revealed a biological "switch" that influences whether an immature blood cell would develop into a red blood cell or a subtype of white blood cell called myeloid cells in response to infection or inflammation within the body.

26 Sep 2018

Research reveals three-dimensional structure of membrane channel that controls blood pressure

New research for the first time reveals the three-dimensional structure of a membrane channel that's critical in controlling blood pressure.

26 Sep 2018

Researchers find molecule that halts, reverts neurodegeneration caused by Parkinson's disease

The small SynuClean-D molecule interrupts the formation of the alpha-synuclein amyloid fibers responsible for the onset of Parkinson's disease, and reverts the neurodegeneration caused by the disease.

25 Sep 2018

Genomic ‘islands’ evolved from viruses can be converted into ‘anti-bacterial drones’

Genomic "islands" that evolved from viruses can be converted into "drones" that disable Staphylococcus aureus, bacteria that are often resistant to antibiotics and pose a threat to safe hospital care, a new study finds.

25 Sep 2018

Environmental biologist explores how songbirds stay slim despite overeating

Noticing that songbirds, such as finches, never seem to get fat despite overeating at bird feeders, London environmental biologist Lewis Halsey wondered whether the amount of energy birds put into singing, fidgeting, or exercising could be adjusted in ways that regulate weight.

24 Sep 2018

New research provides insight into the way human brain connects episodic memories to solve problems

Humans have the ability to creatively combine their memories to solve problems and draw new insights, a process that depends on memories for specific events known as episodic memory.

24 Sep 2018

Scientists discover and characterize human skeletal stem cells

Human skeletal stem cells that become bone, cartilage, or stroma cells have been isolated from fetal and adult bones. This is the first time that skeletal stem cells, which had been observed in rodent models, have been identified in humans.

24 Sep 2018

Ecstasy drug makes octopuses more social

When people take MDMA, the drug popularly known as ecstasy, a rush of serotonin, dopamine, and oxytocin produces feelings of emotional closeness and euphoria, making people more interested than they would normally be in connecting and sharing with other people.

24 Sep 2018

Researchers propose mechanism by which ASTN2 protein defects lead to brain disorders

In the brain, as in business, connections are everything. To maintain cellular associates, the outer surface of a neuron, its membrane, must express particular proteins--proverbial hands that reach out and greet nearby cells. And, like a creepily long handshake, surface molecules can overstay their welcome: A protein that lingers too long on the membrane may compromise the connections, or synapses, between cells.

24 Sep 2018

Overlooked immune cells could play a key role in cancer immunotherapy, claims new study

Cancer immunotherapy is a relatively new method of treating cancer and has succeeded with some refractory tumors. However, it doesn’t always work, why not?

21 Sep 2018

Scientists report conserved role for serotonin in mediating social behavior in octopus, humans

The mood-altering drug MDMA - which promotes positive, friendly social interactions in humans by inhibiting serotonin uptake in nerve cells - has a similar behavioral effect in an octopus species, scientists report today.

21 Sep 2018

Novel mathematical approach uncovers existence of unsuspected biological cycles

A novel mathematical approach has uncovered that some animal cells have robust 12-hour cycles of genetic activity, in addition to circadian or 24-hour cycles.

20 Sep 2018

Body organs undergo structural changes in response to diet

Body organs such as the intestine and ovaries undergo structural changes in response to dietary nutrients that can have lasting impacts on metabolism, as well as cancer susceptibility, according to Carnegie's Rebecca Obniski, Matthew Sieber, and Allan Spradling.

20 Sep 2018

Progenitor cells for human bone and cartilage have been identified

Research published today describes for the first time the identification of human skeletal stem cells. The discovery may enable the development of novel therapeutic strategies for diseases that cause skeletal degeneration.

20 Sep 2018

Cell Biology

Not all P53 mutations cause skin cancer

New cell-based profiling service from RBC and Promega

Minicells play key function in self-preservation of bacteria, finds study

Researchers uncover molecular underpinnings of liver regeneration

Drosophila study shows chromosomal instability promotes invasive behavior in human tumors

Researchers to build 3D map of human cells and tissues

Biological 'switch' influences whether immature blood cells differentiate into red or white blood cells

Research reveals three-dimensional structure of membrane channel that controls blood pressure

Researchers find molecule that halts, reverts neurodegeneration caused by Parkinson's disease

Genomic ‘islands’ evolved from viruses can be converted into ‘anti-bacterial drones’

Environmental biologist explores how songbirds stay slim despite overeating

New research provides insight into the way human brain connects episodic memories to solve problems

Scientists discover and characterize human skeletal stem cells

Ecstasy drug makes octopuses more social

Researchers propose mechanism by which ASTN2 protein defects lead to brain disorders

Overlooked immune cells could play a key role in cancer immunotherapy, claims new study

Scientists report conserved role for serotonin in mediating social behavior in octopus, humans

Novel mathematical approach uncovers existence of unsuspected biological cycles

Body organs undergo structural changes in response to diet

Progenitor cells for human bone and cartilage have been identified

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