Cell Biology

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New UCLA study could elucidate certain causes of infertility and miscarriage

A new study in the journal Nature Cell Biology has uncovered information about a key stage that human embryonic cells must pass through just before an embryo implants. The research, led by UCLA biologist Amander Clark, could help explain certain causes of infertility and spontaneous miscarriage.

26 Apr 2018

Scientists 3D print cells onto human hand

Scientists have developed a ground-breaking technology that can print electronics and cells directly onto skin and could be used to provide chemical sensors for soldiers in combat zones and new treatments for skin disorders.

26 Apr 2018

Researchers target telomerase for killing NRAS-mutant melanoma cells

Targeting telomerase was effective at killing NRAS-mutant melanoma cells, and the impact was further enhanced when the strategy was paired with an inhibitor of mitochondrial function, according to study results by The Wistar Institute published in Oncogene.

26 Apr 2018

Doctors cure sickle cell patients using allogeneic stem cells

Seven adults with sickle cell disease have been cured by doctors at the University of Illinois Hospital, thanks to the development of a new protocol for stem cell transplantation.

25 Apr 2018

Salk researchers develop new glioblastoma model using gene-edited organoids

Glioblastoma multiforme (GBM) is an incredibly deadly brain cancer and presents a serious black box challenge. It's virtually impossible to observe how these tumors operate in their natural environment and animal models don't always provide good answers.

25 Apr 2018

New technique harnesses 'natural barcodes' to facilitate better cell tracking

Each of us carries in our genomes about 10 million genetic variations called single nucleotide polymorphisms, which represent a difference of just one letter in the genetic code.

24 Apr 2018

Scientists identify new DNA structure within living human cells

For the first time, a team of researchers have identified a new DNA structure inside cells that has an entirely different shape to the iconic “double helix” shape uncovered by Watson and Crick in 1953.

24 Apr 2018

Scientists use haploid stem cells to create an atlas of the human genome

Researchers have used a sophisticated gene-editing technology to create a new type of embryonic stem cell and an atlas of the human genome.

24 Apr 2018

Scientists use haploid stem cells to create an atlas of the human genome

Researchers have used a sophisticated gene-editing technology to create a new type of embryonic stem cell and an atlas of the human genome.

24 Apr 2018

Role of extrachromosomal pieces of DNA in cancer development and treatment resistance

Glioblastoma is the most common and aggressive form of brain cancer. Response to standard-of-care treatment is poor, with a two-year survival rate of only 15 percent.

24 Apr 2018

Cytochalasin B-induced membrane vesicles successfully tested as vector for anti-tumor drug delivery

Extracellular vesicles (EV) represent a promising vector system for biomolecules and drug delivery due to their natural origin and participation in intercellular communication.

24 Apr 2018

Researchers trigger E. coli’s toxin-antitoxin system to inhibit bacterial growth

According to new research, the toxin-antitoxin (TA) system found within E. coli can be induced to inhibit the growth of the bacterium. This may have important consequences for human infection.

23 Apr 2018

Study examines how higher-order gene combinations help maintain normal cell physiology

We inherit many traits from our parents including the color of our eyes and hair. Unfortunately, we also inherit risk factors for certain diseases such as cancer, heart disease, and diabetes. Understanding those genetic connections can help prevention efforts and develop new life-saving treatments to combat these diseases.

20 Apr 2018

New microscope reveals how cells behave in 3D and real time inside living organisms

Astronomers developed a "guide star" adaptive optics technique to obtain the most crystal-clear and precise telescopic images of distant galaxies, stars and planets. Now a team of scientists, led by Nobel laureate Eric Betzig, PhD, are borrowing the very same trick.

20 Apr 2018

EPFL becomes part of Chan Zuckerberg’s project to develop Human Cell Atlas

"The automated single-cell analysis pipeline is a software tool that catalyzes interdisciplinary work as it allows non-expert labs to engage in high-level genomic research that otherwise would require significant computational expertise," explains Professor Bart Deplancke, director of a lab at EPFL's Institute of Bioengineering.

20 Apr 2018

Novel microscope allows real-time, 3-D visualization of cells

Scientists at the Howard Hughes Medical Institute's Janelia Research Campus have developed a microscope which combines two imaging techniques to capture live 3-D images of cells.

20 Apr 2018

New CRISPR tool allows DNA editing outside of the cell

Researchers have developed a cell free method of gene editing, which uses a new version of the CRISPR tool that can edit DNA outside of the cell. This technique could revolutionize cancer care.

20 Apr 2018

AYOXXA introduces new LUNARIS Mouse 12-Plex Th17 Kit for quantitative analysis of Th17 cell biology

AYOXXA Biosystems GmbH, an international biotechnology company, focused on the development of innovative multiplex protein analysis technologies enabling translational research in basic and clinical research, today announced the expansion of its catalogue of immunoassays for multiplex protein analysis with the introduction of LUNARIS™ Mouse 12-Plex Th17 Kit for the quantitative analysis of soluble mouse T helper 17 (Th17) cell-related markers.

20 Apr 2018

Genetic make-up impacts long-term effectiveness of phobia treatment

Researchers have discovered that variations in the efficacy of psychological treatment for phobias are associated with the serotonin transporter gene.

19 Apr 2018

Novel biomarker can distinguish between benign and malignant lung nodules

Researchers report a newly developed biomarker was 98% effective at distinguishing between benign and malignant lung nodules in a recent multicentre clinical trial.

18 Apr 2018