Cell Biology

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Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

My research uses budding yeast as a tool for synthetic biology, and also in chemical and functional genomic applications. We are interested in understanding molecular mechanisms and metabolic pathways of yeast for drug discovery.

From Tecan 27 Sep 2017

Sophisticated 'social control' system allows embryos to protect purity of pluripotent cell population

A sophisticated system of 'social control' operating between neighboring cells allows embryos to protect the purity of their pluripotent cell population, which is able to generate all body tissues.

27 Sep 2017

Adding, removing water from a stem cell can determine its role as bone or fat

Adding or removing water from a stem cell can change the destiny of the cell, researchers have discovered in a new study published in the Proceedings of the National Academy of Sciences.

27 Sep 2017

Rutgers scientists use genetic engineering technique to create brain cells for studying Tourette’s

Scientists at Rutgers University-New Brunswick used a genetic engineering technique for the first time to create brain cells from the blood cells of individuals in a three-generation family with Tourette syndrome to help determine what causes the disease.

25 Sep 2017

Forgotten strands of DNA induce 'big bang' of immune cell development

Intricate human physiological features such as the immune system require exquisite formation and timing to develop properly. Genetic elements must be activated at just the right moment, across vast distances of genomic space.

21 Sep 2017

Lonza launches new CytoSMART 2 System for capturing higher-resolution images of live cells

Lonza has today introduced the CytoSMART™ 2 System, an updated version of Lonza’s popular CytoSMART™ System for live cell imaging. The CytoSMART™ 2 Device features an advanced optical system and more powerful camera unit, which enables researchers to capture higher-resolution images of their cell cultures.

21 Sep 2017

Breakthrough research allows scientists to program cells like computers for battling against diseases

Cells can be programmed like a computer to fight cancer, influenza, and other serious conditions - thanks to a breakthrough in synthetic biology by the University of Warwick.

18 Sep 2017

Research: The body's fat-metabolism causes detoxification of harmful substances from blood sugar

For several years, medical researchers, doctors, and dieticians have known that a low carbohydrate diet and plentiful fat can prevent a range of lifestyle and age-related diseases and thus promote healthy aging. But researchers from around the world have not been able to explain why this is the case.

18 Sep 2017

Penn study provides insight into how cells maintain identity during replication

Prior to cell division, chromosomes are seemingly a jumbled mess. During cell division, parent cell chromosomes and their duplicates sort themselves out by condensing, becoming thousands of times more compact than at any other time.

15 Sep 2017

Heidelberg researchers gain new insights into formation of blood vessels

New insights into the development of the vascular system: researchers in the team of Dr Carmen Ruiz de Almodóvar of the Heidelberg University Biochemistry Center have discovered a crucial biological step that regulates the formation of blood vessels.

15 Sep 2017

‘Nanokicking’ technology allows scientists to grow 3D mineralized bone tissue

Researchers from the Universities of Glasgow, Strathclyde, the West of Scotland and Galway have grown three-dimensional samples of mineralized bone from human mesenchymal stem cells for the first time without typical osteoinductive media.

15 Sep 2017

DNA robot sorts molecules without external input

Researchers at the California Institute of Technology have developed an autonomous molecular machine comprising a single strand of DNA that can move around, collect specific molecules and sort them into predefined locations. Furthermore, this nanobot has been designed in such a way that requires no external source of energy or instruction.

15 Sep 2017

TwinGuard freezer range from Panasonic enable secure sample storage

Panasonic Biomedical Sales Europe B.V. has introduced two new TwinGuard Ultra Low Temperature Upright Freezers. The new models include enhanced features that improve the footprint and ease-of-use of the TwinGuard range for highly secure storage of high value samples. The new MDF-DU502VX-PE and MDF-DU702VX-PE provide an internal capacity of 528 litres and 729 litres, respectively.

From PHC Europe B.V. 14 Sep 2017

Researchers develop fluorescent sensors for detecting, tracking GTP levels in living cells

For several decades, scientists have recognized the key role that a molecule known as GTP, one of the building blocks of RNA, plays in the development of cancer and other diseases.

13 Sep 2017

Portuguese researchers reveal mechanism of nuclei movement within muscle cells

A group of researchers at Instituto de Medicina Molecular Lisboa has revealed the mechanism by which cellular nuclei reach their position within muscle cells.

11 Sep 2017

Study provides first structural glimpse of circadian clock's molecular machinery

Scientists have long known that circadian clocks- biochemical oscillators that control physiology, metabolism and behavior on a roughly 24-hour cycle- are present in all forms of life, including animals, plants, fungi and some types of bacteria. However, the molecular mechanisms that "run" these systems remain largely unknown.

7 Sep 2017

Seeing the full picture, real-time analysis of live-cells

Every cell is a miniature factory taking in raw material (extracellular signals) and processing it to produce something (a biological response). But unlike a factory that can be easily tweaked to run at steady-state and look the same from day to day, cells are dynamic.

From Sartorius 7 Sep 2017

Study identifies novel source for brain's development

A study conducted by a team of researchers at the New York University has found an unexpected source for the development of the brain. According to the research, which was published in the journal Science, a group of non-neuronal cells called glia, which were previously considered as passive support cells, are important for the development of nerve-cells present in the brain.

5 Sep 2017

Antibiotics may kill bacteria differently in vitro vs in vivo

Understanding exactly how antibiotics work (or don’t work) is crucial for developing alternative treatment strategies, not only to target new “superbugs,” but also to make existing drugs more effective against their targets.

5 Sep 2017

Scientists show how receptors for drugs act inside cells

G protein-coupled receptors are the key target of a large number of drugs. Würzburg scientists have now been able to show more precisely how these receptors act in the cell interior.

5 Sep 2017

Cell Biology

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

Sophisticated 'social control' system allows embryos to protect purity of pluripotent cell population

Adding, removing water from a stem cell can determine its role as bone or fat

Rutgers scientists use genetic engineering technique to create brain cells for studying Tourette’s

Forgotten strands of DNA induce 'big bang' of immune cell development

Lonza launches new CytoSMART 2 System for capturing higher-resolution images of live cells

Breakthrough research allows scientists to program cells like computers for battling against diseases

Research: The body's fat-metabolism causes detoxification of harmful substances from blood sugar

Penn study provides insight into how cells maintain identity during replication

Heidelberg researchers gain new insights into formation of blood vessels

‘Nanokicking’ technology allows scientists to grow 3D mineralized bone tissue

DNA robot sorts molecules without external input

TwinGuard freezer range from Panasonic enable secure sample storage

Researchers develop fluorescent sensors for detecting, tracking GTP levels in living cells

Portuguese researchers reveal mechanism of nuclei movement within muscle cells

Study provides first structural glimpse of circadian clock's molecular machinery

Seeing the full picture, real-time analysis of live-cells

Study identifies novel source for brain's development

Antibiotics may kill bacteria differently in vitro vs in vivo

Scientists show how receptors for drugs act inside cells

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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