Cell Biology

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Honokiol inhibits replication of SARS-CoV-2 in several cell types

A compound called honokiol, which is found in the bark of multiple species of magnolia tree, inhibits replication of SARS-CoV-2 virus in several types of cells, according to a team of researchers in the Netherlands.

22 May 2023

AI-based method predicts small molecule substrates of enzymes

Enzymes are the molecule factories in biological cells. However, which basic molecular building blocks they use to assemble target molecules is often unknown and difficult to measure.

22 May 2023

Newly discovered molecule effectively destroys senescent cells

Over time, the body's cells stop working properly and begin to accumulate, which eventually leads to tissues aging.

22 May 2023

New vaccine concept could lead to a new generation of vaccines against SARS-CoV-2

Researchers at the University of Basel have developed a new approach for a vaccine against COVID-19.

22 May 2023

New cell-like transport system could pave the way for development of artificial cells

Biophysicists have designed a new cell-like transport system that represents an important milestone on the road to artificial cells.

19 May 2023

Researchers reveal the cooperative effect of multiple oscillatory signals in biological systems

Oscillatory dynamics in fundamental biological processes, such as circadian clocks, segmentation, and transcription factor responses, requires precise quantitative control for proper cell regulation and fate decisions.

19 May 2023

Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection

Genetic alterations that give rise to a rare, fatal disorder known as MOGS-CDG paradoxically also protect cells against infection by viruses.

19 May 2023

Mutation in a ribosomal protein leads to impaired cardiac contractility in mice

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.

19 May 2023

Researchers discover molecular pathway that mediates cancer-associated muscle atrophy

Nearly half of all cancer patients suffer from excessive weight loss due to the loss of adipose and skeletal muscle tissues, or cachexia.

18 May 2023

Liver cells can act on the central clock and modify circadian behavior

University of Queensland-led research has revealed liver cells influence the body's internal circadian clock, which was previously believed to be solely controlled by the brain.

18 May 2023

Change in liver clock could affect synchronization of the circadian cycle

Organisms rely on a biological clock known as the 'circadian' clock to regulate their activity according to the time of day.

17 May 2023

Researchers identify a major stem cell variant in lungs of patients with idiopathic pulmonary fibrosis

A pair of internationally renowned stem cell cloning experts at the University of Houston is reporting their findings of variant cells in the lungs of patients with Idiopathic Pulmonary Fibrosis (IPF) which likely represent key targets in any future therapy for the condition.

17 May 2023

Study establishes a mechanistic link between obesity and oral cancer immune escape

A team from the University of Michigan Rogel Cancer Center and School of Dentistry, led by Yu Leo Lei, D.D.S., Ph.D., have identified a mechanism in mice for how obesity affects some oral cancers' ability to escape from the immune system.

16 May 2023

Glycosylation enzyme plays a crucial role in brain development, study shows

The MGAT5 glycosylation enzyme plays a crucial role in brain development, according to a study by University of California, Irvine researchers, a discovery that may contribute to new therapeutic purposes for neural stem cells.

16 May 2023

Molecular mechanism behind a DNA repair pathway revealed

A new study adds to an emerging, radically new picture of how bacterial cells continually repair faulty sections of their DNA.

16 May 2023

New process for automated and highly accurate reporting of NGS-based clonality testing

A new research paper was published in Oncotarget's Volume 14 on May 12, 2023, entitled, "Development and implementation of an automated and highly accurate reporting process for NGS-based clonality testing."

16 May 2023

Researchers report the role of RNA-binding protein Msi 1 to maintain breast cancer stem cells

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 9, entitled, "Increased expression of musashi 1 on breast cancer cells has implication to understand dormancy and survival in bone marrow."

16 May 2023

Cell Biology

Honokiol inhibits replication of SARS-CoV-2 in several cell types

AI-based method predicts small molecule substrates of enzymes

Newly discovered molecule effectively destroys senescent cells

New vaccine concept could lead to a new generation of vaccines against SARS-CoV-2

New cell-like transport system could pave the way for development of artificial cells

Researchers reveal the cooperative effect of multiple oscillatory signals in biological systems

Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection

Mutation in a ribosomal protein leads to impaired cardiac contractility in mice

Researchers discover molecular pathway that mediates cancer-associated muscle atrophy

Liver cells can act on the central clock and modify circadian behavior

Change in liver clock could affect synchronization of the circadian cycle

Researchers identify a major stem cell variant in lungs of patients with idiopathic pulmonary fibrosis

Study establishes a mechanistic link between obesity and oral cancer immune escape

Glycosylation enzyme plays a crucial role in brain development, study shows

Molecular mechanism behind a DNA repair pathway revealed

New process for automated and highly accurate reporting of NGS-based clonality testing

Researchers report the role of RNA-binding protein Msi 1 to maintain breast cancer stem cells

New SEISMIC facility could improve our understanding of infectious diseases, aging and cancers

Novel tool paves the way for automated identification and localization of proteins in cells

Weight loss leads to an increase in skeletal muscle mitochondrial energy production efficiency

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