Cell Biology

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New technology can rapidly analyze the metabolic state of lipids in cells

Professor Itaru Hamachi, Lecturer Tomonori Tamura, and Assistant Professor Masaki Tsuchiya of Kyoto University have developed a new technology called O-ClickFC (Organelle-selective click labeling with flow cytometry), which can, at a very high speed, analyze the metabolic state of lipids in cells.

27 Mar 2023

Enhancing the effectiveness of immunization against certain cancers

In addition to an antigen, many vaccines also contain substances, called adjuvants, which stimulate the immune system.

27 Mar 2023

Monocytes may be a stable reservoir of HIV in patients taking antiretroviral therapy

To develop treatments that may one day entirely rid the body of HIV infection, scientists have long sought to identify all of the places that the virus can hide its genetic code.

27 Mar 2023

Circadian rhythms govern cancer progression and metastasis

Your circadian rhythm doesn't just govern your sleeping schedule; it can also impact cancer development, diagnosis, and treatment.

24 Mar 2023

New high resolution model of the human hippocampus CA1 area developed

A new high resolution model of the CA1 region of the human hippocampus has been developed by the Institute of Biophysics of the Italian National Research Council and University of Modena e Reggio Emilia, part of the Human Brain Project.

24 Mar 2023

Screening cultured stem cells for genetic mutations could ensure the accuracy of disease models

Induced pluripotent stem cells offer great therapeutic potential and are a valuable tool for understanding how different diseases develop.

24 Mar 2023

Genes known to control eye color are essential for retinal health

Metabolic pathways consist of a series of biochemical reactions in cells that convert a starting component into other products.

23 Mar 2023

Study provides evidence for a strong role of autophagy in controlling intracellular infections

Researchers at the Francis Crick Institute have found that the body's process of removing old and damaged cell parts, is also an essential part of tackling infections that take hold within our cells, like TB.

23 Mar 2023

New discovery could help target the causes of aging and cancer development

A protein complex prevents the repair of genome damage in human cells, in mice and in the nematode Caenorhabditis elegans, a team of researchers at the University of Cologne has discovered.

23 Mar 2023

Modulating the function of immune cells to recover aging muscle's regenerative capacity

Muscle is able to regenerate through a process that involves multiple steps and players, including the immune system.

23 Mar 2023

Inhibition of cell wall formation arrests staphylococcal cell division

We still do not understand exactly how antibiotics kill bacteria. However, this understanding is necessary if we want to develop new antibiotics.

23 Mar 2023

Study discovers a protein controlling resistance to chemotherapy

Despite the recent development of new targeted therapies, chemotherapies remain the most frequently used treatment to treat patients suffering from advanced cancers.

22 Mar 2023

Researchers discover how a single mechanosensitive protein induces fibrosis

Researchers from Kyushu University have found how a single mechanosensitive protein induces the process that thickens and scars tissue, known as fibrosis. The protein, called VGLL3, was shown to contribute to fibrosis in multiple organs.

22 Mar 2023

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Memory B cells play a critical role to provide long-term immunity after a vaccination or infection. In a study published in the journal Immunity, researchers describe a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans.

22 Mar 2023

High-fat and high-sugar foods can rewire the brain

Chocolate bars, crisps and fries - why can't we just ignore them in the supermarket? Researchers at the Max Planck Institute for Metabolism Research in Cologne, in collaboration with Yale University, have now shown that foods with a high fat and sugar content change our brain: If we regularly eat even small amounts of them, the brain learns to consume precisely these foods in the future.

22 Mar 2023

New encoding strategy for single-cell tomograms streamlines data handling and storage

Single-cell analysis is a powerful biomedical technique used in various fields of biology and medicine to identify rare cell populations, track cell development and differentiation, understand disease mechanisms and develop personalized therapies, but it generates large amounts of data that can be difficult to manage.

22 Mar 2023

Researchers identify the cellular glitches underlying a rare genetic disorder

The cellular glitches underlying a rare genetic disorder called activated PI3K Delta syndrome 2 (APDS2) have been identified by researchers at the Garvan Institute of Medical Research. The disorder is caused by genetic variations that disrupt immune cell signaling through a protein called PI3K.

21 Mar 2023

Vaginal sex can shape the composition of urethral microbiome in healthy men

Contrary to common beliefs, your urine is not germ free. In fact, a new study shows that the urethra of healthy men is teeming with microbial life and that a specific activity - vaginal sex - can shape its composition.

21 Mar 2023

Keeping stem cells clean and tidy is an integral step to promoting a long healthspan

In humanity's ongoing quest for the elixir of life, the science keeps pointing to stem cells. Research increasingly shows that maintaining stem cell fitness promotes a long healthspan, and new findings show keeping stem cells clean and tidy is an integral step.

21 Mar 2023

Study highlights the role of intestinal T cells in modifying psychological stress responses

In experiments with mice and humans, a team led by Johns Hopkins Medicine researchers says it has identified a particular intestinal immune cell that impacts the gut microbiome, which in turn may affect brain functions linked to stress-induced disorders such as depression.

21 Mar 2023

Cell Biology

New technology can rapidly analyze the metabolic state of lipids in cells

Enhancing the effectiveness of immunization against certain cancers

Monocytes may be a stable reservoir of HIV in patients taking antiretroviral therapy

Circadian rhythms govern cancer progression and metastasis

New high resolution model of the human hippocampus CA1 area developed

Screening cultured stem cells for genetic mutations could ensure the accuracy of disease models

Genes known to control eye color are essential for retinal health

Study provides evidence for a strong role of autophagy in controlling intracellular infections

New discovery could help target the causes of aging and cancer development

Modulating the function of immune cells to recover aging muscle's regenerative capacity

Inhibition of cell wall formation arrests staphylococcal cell division

Study discovers a protein controlling resistance to chemotherapy

Researchers discover how a single mechanosensitive protein induces fibrosis

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

High-fat and high-sugar foods can rewire the brain

New encoding strategy for single-cell tomograms streamlines data handling and storage

Researchers identify the cellular glitches underlying a rare genetic disorder

Vaginal sex can shape the composition of urethral microbiome in healthy men

Keeping stem cells clean and tidy is an integral step to promoting a long healthspan

Study highlights the role of intestinal T cells in modifying psychological stress responses

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