Cell Biology

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Penn researchers discover new type of cell that may play key role in human lung diseases

A new type of cell that resides deep within human lungs and may play a key role in human lung diseases has been discovered by researchers at the Perelman School of Medicine at the University of Pennsylvania.

3 Apr 2023

Probiotic E. coli secretes proteins of therapeutic value into its surroundings

Humans are colonized with thousands of bacterial strains. Researchers are now focused on genetically modifying such bacteria to enhance their intrinsic therapeutic properties.

31 Mar 2023

Transposable elements in various cancers could be used to harness novel immunotherapies

New research from Washington University School of Medicine in St. Louis suggests that transposable elements in various cancers potentially may be used to harness novel immunotherapies against tumors that don't typically respond to immune-based treatments. Shown is a 3D rendering of cancer cells.

31 Mar 2023

Study focuses on a novel mechanism of the body's regulation of salt balance

A new study led by Marshall University researchers focuses on a novel mechanism of the body's regulation of salt balance.

31 Mar 2023

Researchers report surprising first steps that promote resistance to commonly prescribed antibiotics

Antibiotic resistance is a global health threat. In 2019 alone, an estimated 1.3 million deaths were attributed to antibiotic resistant bacterial infections worldwide.

31 Mar 2023

Researchers create a visualization of the full-length human BRCA2 protein at single molecule level

Using a self-built inverted microscope complete with laser optical tweezers to capture DNA, Yale Cancer Center and University of California Davis researchers for the first time created a visualization of the full-length human BRCA2 protein at the single molecule level.

31 Mar 2023

High consumption of common artificial sweetener lowers activation of T-cells in mice

Scientists at the Francis Crick Institute have found that high consumption of a common artificial sweetener, sucralose, lowers activation of T-cells, an important component of the immune system, in mice.

31 Mar 2023

Researchers develop new method to make rare cell types and disease patterns visible in tissue

The human body contains more than 30 trillion cells. Until recently, the sheer number of cells in the organism meant that approaches to understanding human diseases and developmental processes based on the analysis of single cells were a futuristic vision.

31 Mar 2023

Groundbreaking technique offers a new way to gain detailed information about organic tissues

A groundbreaking technique developed by researchers affiliated with the USC Michelson Center for Convergent Bioscience presents a new way of gathering and organizing highly detailed information about organic tissues in record time.

31 Mar 2023

New model of DNA flexibility opens up the possibility of getting closer to the chromatin scale

In both physics and chemistry, the mesoscopic scale refers to the length scale on which the properties of a material or phenomenon can be studied, without entering into a discussion about the behavior of individual atoms.

31 Mar 2023

New microscopy method illuminates the mechanics of embryo development

In 1922, French physicist Léon Brillouin predicted an interesting phenomenon – when light is shone on a material, it interacts with the naturally occurring thermal vibrations within it, exchanging some energy in the process.

30 Mar 2023

New therapeutic approach to eliminate aging cells by boosting anti-viral immune response

Aging, or senescent cells, which stop dividing but don't die, can accumulate in the body over the years and fuel chronic inflammation that contributes to conditions such as cancer and degenerative disorders.

30 Mar 2023

New model captures the complex shapes and biophysical properties of neurons

The thalamus and thalamic reticular nucleus are situated at the heart of the mammalian brain and are known to play a key role in a wide range of functions, including the transmission of sensory information to the cortex and the transition between brain states such as sleep and wakefulness.

30 Mar 2023

Study shows how neutrophils play a key role in cancer immunotherapy success

Cancer immunotherapies that recruit a patient's own immune system to destroy tumors have transformed the treatment of many types of cancer. Yet these therapies do not elicit universally good treatment responses.

30 Mar 2023

The origin of congenital coronary fistulae discovered

Scientists of the Department of Animal Biology of the University of Malaga have discovered the cellular mechanism that originates coronary arterio-ventricular fistulae, a congenital anomaly that, in severe cases, may result in death.

30 Mar 2023

Cellular senescence and extracellular vesicles partner to play a role in triggering amyloidosis

A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 5, entitled, "Senescence and extracellular vesicles: novel partners in vascular amyloidosis."

29 Mar 2023

Diverse subset of T-cell clones plays a role in the antitumor effects of immune checkpoint inhibitors

Immune checkpoint inhibitors (ICIs) are widely sought after for the treatment of different types of cancers. Unfortunately, only 20–30% patients with cancer respond to ICI treatment.

29 Mar 2023

Study paves the way for wider applications of cell reprogramming in medicine

Sanford Burnham Prebys researchers have identified a group of proteins that could be the secret to cellular reprogramming, an emerging approach in regenerative medicine in which scientists transform cells to repair damaged or injured body tissues.

29 Mar 2023

Study investigates how loss of angulin-1/LSR affects the malignancy of lung adenocarcinoma

A new research paper was published in Oncotarget's Volume 14 on March 24, 2023, entitled, "Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells."

29 Mar 2023

New engineered bioadhesive sealant for more effective surgical wound management

As part of a collaborative effort, scientists from the Terasaki Institute for Biomedical Innovation (TIBI) have employed inventive chemistry to produce an injectable biomaterial with significantly improved adhesive strength, stretchability, and toughness.

29 Mar 2023

Cell Biology

Penn researchers discover new type of cell that may play key role in human lung diseases

Probiotic E. coli secretes proteins of therapeutic value into its surroundings

Transposable elements in various cancers could be used to harness novel immunotherapies

Study focuses on a novel mechanism of the body's regulation of salt balance

Researchers report surprising first steps that promote resistance to commonly prescribed antibiotics

Researchers create a visualization of the full-length human BRCA2 protein at single molecule level

High consumption of common artificial sweetener lowers activation of T-cells in mice

Researchers develop new method to make rare cell types and disease patterns visible in tissue

Groundbreaking technique offers a new way to gain detailed information about organic tissues

New model of DNA flexibility opens up the possibility of getting closer to the chromatin scale

New microscopy method illuminates the mechanics of embryo development

New therapeutic approach to eliminate aging cells by boosting anti-viral immune response

New model captures the complex shapes and biophysical properties of neurons

Study shows how neutrophils play a key role in cancer immunotherapy success

The origin of congenital coronary fistulae discovered

Cellular senescence and extracellular vesicles partner to play a role in triggering amyloidosis

Diverse subset of T-cell clones plays a role in the antitumor effects of immune checkpoint inhibitors

Study paves the way for wider applications of cell reprogramming in medicine

Study investigates how loss of angulin-1/LSR affects the malignancy of lung adenocarcinoma

New engineered bioadhesive sealant for more effective surgical wound management

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