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New delivery system for combination of 2 FDA approved drugs to fight HIV

A University of Minnesota research team featuring researchers from the Institute for Molecular Virology, School of Dentistry and Center for Drug Design has developed a new delivery system for a combination of two FDA approved drugs that may serve as an effective treatment for the human immunodeficiency virus (HIV).

31 Aug 2013

Texas A&M University biologist receives federal grant to study Clostridium difficile

A Texas A&M University biologist has received a federal grant to study the fecal samples of hundreds of people to better understand the gut bacteria Clostridium difficile - the cause of some 14,000 deaths a year in America - and to help lay the basic science foundation to develop drugs to combat its deadly results.

30 Aug 2013

Researchers discover new gene mutations which cause devastating mitochondrial disorders

Researchers have identified a novel disease gene in which mutations cause rare but devastating genetic diseases known as mitochondrial disorders.

30 Aug 2013

Researchers identify and track strains of antibiotic resistant salmonella

Continuing research on Salmonella may enable researchers to identify and track strains of antibiotic resistant bacteria as they evolve and spread, according to researchers in Penn State's College of Agricultural Sciences.

30 Aug 2013

Eight additional cases of MERS-CoV infection confirmed in Saudi Arabia

WHO has been informed of an additional eight laboratory-confirmed cases of Middle East respiratory syndrome coronavirus infection in Saudi Arabia.

29 Aug 2013

Researchers identify novel mechanism that particular superbug uses to fend off antibiotic

Investigators working to stem the spread of antibiotic-resistant bacteria have taken a major step in their efforts to develop new treatments.

29 Aug 2013

New method that targets mosquito larvae and pupae may help control malaria

A malaria control method that targets mosquito larvae and pupae as they mature in standing water could be an important supplementary measure in the fight against the disease, according to a new report.

29 Aug 2013

Research findings may help scientists develop anthrax treatments for humans

Researchers at the National Institute of Allergy and Infectious Diseases and the National Heart, Lung, and Blood Institute, both part of the National Institutes of Health, have identified the cells in two distinct areas of the body that are simultaneously targeted for damage by anthrax toxins, eventually causing illness and sometimes death. Their findings, which appeared online today in Nature, are based on testing in mice.

29 Aug 2013

FDA categorizes Cepheid's Xpert MTB/RIF test as 'Moderate Complexity' under CLIA

Cepheid today announced the U.S. Food & Drug Administration has categorized Cepheid's Xpert MTB/RIF test as 'Moderate Complexity' under the Clinical Laboratory Improvement Amendments.

28 Aug 2013

Infant rotavirus vaccination reduced severe gastroenteritis among U.S. children

"Implementation of infant rotavirus vaccination in 2006 has substantially reduced the burden of severe gastroenteritis among U.S. children younger than 5 years," write Paul A. Gastanaduy, M.D., M.P.H., of the Centers for Disease Control and Prevention, Atlanta, and colleagues. "Whether indirect protection (due to reduced transmission of rotavirus) extends to adults remains unclear."

28 Aug 2013

HCV treatment with sofosbuvir and ribavirin results in sustained virologic response

Treatment of chronic hepatitis C virus genotype 1 infection with the interferon-free regimen of sofosbuvir and ribavirin resulted in a high sustained virologic response rate in a patient population with unfavorable treatment characteristics, according to a study in the August 28 issue of JAMA.

28 Aug 2013

Study: Apoptosis triggers alternate replication pathway in HHV

Washington, DC-Researchers from Children's National Medical Center have found that an alternate, "escape" replication process triggered by apoptosis-the process of cell death or "cell suicide"-appears to be common in human herpesviruses (HHV).

28 Aug 2013

New mothers and obese people have higher risk of severe outcomes from influenza

Although up to 500,000 people world-wide die of severe influenza each year, there has been no clear evidence about who is susceptible for influenza complications and it may not be who people think, says a study from McMaster University.

28 Aug 2013

BiondVax: Priming with universal flu vaccine makes conventional bird flu vaccine effective against pandemic strains

BiondVax announced today that priming with universal flu vaccine before boosting with a conventional bird flu H5N1 vaccine (containing a single strain from Clade 1) resulted in mice exhibiting a significantly higher level of immunity to the strain contained in the conventional bird flu vaccine and in addition, broadened immunity to other H5N1 flu strains (from Clade 2).

27 Aug 2013

Study reveals role of cadherin receptor BT-R3 in killing action of Cry4B mosquito toxin

Researchers at The University of Texas at Dallas (UTD), led by Dr. Lee Bulla, have demonstrated for the first time the selective cytotoxicity of Bacillus thuringiensis subsp. israelensis Cry4B toxin is mediated by BT-R3.

27 Aug 2013

HIV-infected people who carry gene face greater risk of contracting cryptococcal disease

HIV-infected people who carry a gene for a specific protein face a 20-fold greater risk of contracting cryptococcal disease, according to a study published in mBio-, the online open-access journal of the American Society for Microbiology.

27 Aug 2013

Engineers create biodegradable needles that penetrate skin and precisely deliver tuberculosis test

Each year, millions of people in the United States get a tuberculosis skin test to see if they have the infection that still affects one third of the world's population. But the standard diagnostic test is difficult to give, because a hypodermic needle must be inserted at a precise angle and depth in the arm to successfully check for tuberculosis.

27 Aug 2013

Powerful new option for treating vasculitis

In a study published in the New England Journal of Medicine, a research consortium that includes the University of Alabama at Birmingham (UAB) has shown that a new drug for vasculitis, a potentially life-threatening auto-immune disease which causes inflammation in blood vessels, is as effective as standard therapy over 18 months.

27 Aug 2013

Sanofi Pasteur reports clinical benefit of Fluzone High-Dose vaccine in preventing influenza

Sanofi Pasteur, the vaccines division of Sanofi, today announced topline results of a large-scale, multi-center efficacy trial in people 65 years of age and older showing a superior clinical benefit of Fluzone High-Dose (Influenza Virus Vaccine) relative to the standard dose of Fluzone vaccine in preventing influenza.

26 Aug 2013

HEALTHY FUTURES project aims to address risk of outbreaks, transmission of VBDs

Important outputs are starting to arise from the HEALTHY FUTURES (Health, environmental change and adaptive capacity) project, which aims to address the risk of outbreaks and transmission of three water-related vector-borne diseases (VBDs) in eastern Africa. HEALTHY FUTURES is now past its halfway point, with less than eighteen months of the project remaining.

26 Aug 2013

Disease/Infection News

New delivery system for combination of 2 FDA approved drugs to fight HIV

Texas A&M University biologist receives federal grant to study Clostridium difficile

Researchers discover new gene mutations which cause devastating mitochondrial disorders

Researchers identify and track strains of antibiotic resistant salmonella

Eight additional cases of MERS-CoV infection confirmed in Saudi Arabia

Researchers identify novel mechanism that particular superbug uses to fend off antibiotic

New method that targets mosquito larvae and pupae may help control malaria

Research findings may help scientists develop anthrax treatments for humans

FDA categorizes Cepheid's Xpert MTB/RIF test as 'Moderate Complexity' under CLIA

Infant rotavirus vaccination reduced severe gastroenteritis among U.S. children

HCV treatment with sofosbuvir and ribavirin results in sustained virologic response

Study: Apoptosis triggers alternate replication pathway in HHV

New mothers and obese people have higher risk of severe outcomes from influenza

BiondVax: Priming with universal flu vaccine makes conventional bird flu vaccine effective against pandemic strains

Study reveals role of cadherin receptor BT-R3 in killing action of Cry4B mosquito toxin

HIV-infected people who carry gene face greater risk of contracting cryptococcal disease

Engineers create biodegradable needles that penetrate skin and precisely deliver tuberculosis test

Powerful new option for treating vasculitis

Sanofi Pasteur reports clinical benefit of Fluzone High-Dose vaccine in preventing influenza

HEALTHY FUTURES project aims to address risk of outbreaks, transmission of VBDs

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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