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Study shows ART has reduced immunosuppression and viremia among PHIV youth

The advent of antiretroviral therapy (ART) has transformed HIV from a death sentence into a chronic disease. In one of the largest studies of perinatally infected HIV (PHIV) patients to date, Agwu, et al, found that the proportion of patients on ART has increased and rates of viremia and advanced immunosuppression have decreased. But the rates of both markers in older patients are higher, according to an article in the Fall issue of The Journal of the Pediatric Infectious Diseases Society (JPIDS).

20 Aug 2013

Second GSK intramuscular quadrivalent influenza vaccine approved by the FDA

GlaxoSmithKline plc [LSE/NYSE: GSK] announced that the U.S. Food and Drug Administration (FDA) has approved FLULAVAL® QUADRIVALENT (Influenza Virus Vaccine) for the active immunization of persons three years of age and older to help prevent disease caused by seasonal influenza (flu) virus subtypes A and B contained in the vaccine.

19 Aug 2013

Powerful mechanism helps viruses evade body's immune response

Researchers at the Salk Institute for Biological Studies have discovered a powerful mechanism by which viruses such as influenza, West Nile and Dengue evade the body's immune response and infect humans with these potentially deadly diseases. The findings may provide scientists with an attractive target for novel antiviral therapies.

19 Aug 2013

Mathematical model to help answer critical questions to large-scale anthrax exposure

If terrorists targeted the United States with an anthrax attack, health care providers and policy makers would need key information - such as knowing the likelihood of an individual becoming infected, how many cases to expect and in what pattern, and how long to give antibiotics - to protect people from the deadly bacteria.

17 Aug 2013

Pre-doctoral students receive International Student Research Fellowships from HHMI

The Howard Hughes Medical Institute has awarded two doctoral students from the Sackler School of Graduate Biomedical Sciences at Tufts University with 2013 International Student Research Fellowships. Seblewongel Asrat, from Ethiopia, studies the bacterium that causes Legionnaires' disease while Jennifer Nwankwo, from Nigeria, studies red blood cell dehydration in sickle cell disease.

17 Aug 2013

Organizations are ill prepared for e-health implementation to respond to pandemic influenza

National and international organizations are ill-prepared to exploit e-health systems in the event of the emergence of a major pandemic disease, according to a research paper to be published in the International Journal of Biomedical Engineering and Technology.

17 Aug 2013

Prion proteins responsible for Mad cow disease, Creutzfeld-Jakob disease

Mad cow disease and its cousin Creutzfeld-Jakob disease cause fatal spongy changes in brain tissue. Today, we know that these diseases are caused by prions, proteins that are folded incorrectly. A team of German researchers have now been able to follow how the diseased proteins aggregate and "infect" healthy ones on the atomic scale. Their report appears in the journal Angewandte Chemie.

16 Aug 2013

Scientists shed new light on molecular causes of age related degenerative disease

An international collaboration jointly led by scientists from Trinity College Dublin has shed new light on the origins and molecular causes of age related degenerative conditions including Motor Neurone Disease (MND). The new perspective provided by this work may lead the way to new treatments and early diagnoses.

16 Aug 2013

Research: MRSA in humans originated in cattle at least 40 years ago

A type of MRSA found in humans originated in cattle at least 40 years ago, new research has found. The study provides clear evidence that livestock were the original source of an MRSA strain which is now widespread in people.

16 Aug 2013

New techniques for predicting severity of seasonal cholera epidemics

In two recently published papers, Tufts University School of Engineering researchers have established new techniques for predicting the severity of seasonal cholera epidemics months before they occur and with a greater degree of accuracy than other methods based on remote satellite imaging.

16 Aug 2013

TSRI scientists discover molecular mechanism by which deadly Ebola virus assembles

Scientists at The Scripps Research Institute (TSRI) have discovered the molecular mechanism by which the deadly Ebola virus assembles, providing potential new drug targets.

16 Aug 2013

Scientists uncover potential drug target for effective therapy against bacterial disease brucellosis

UC Davis scientists have uncovered a potential drug target for the development of an effective therapy against the debilitating, chronic form of the bacterial disease brucellosis, which primarily afflicts people in Mediterranean and Middle Eastern countries.

16 Aug 2013

Intervention delivered through mobile phones to HIV/AIDS-positive smokers increased cessation rates

A smoking-cessation intervention delivered through mobile phones to HIV/AIDS-positive smokers increased cessation rates compared to standard care, according to research published online in Clinical Infectious Diseases.

16 Aug 2013

Investigators link acute viral infections to development of COPD

Investigators at Washington University School of Medicine in St. Louis have described another link in the chain of events that connect acute viral infections to the development of chronic obstructive pulmonary disease (COPD).

16 Aug 2013

Probiotic does not prevent clinical relapse in patients with Crohn's disease

Despite previous data showing beneficial effects, the probiotic Saccharomuces boulardii (S. boulardii) does not prevent clinical relapse in patients with Crohn's disease, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

16 Aug 2013

Children exposed to HIV in womb are no more likely to show language delays

Children who were exposed to HIV in the womb whose mothers received anti-HIV medications during pregnancy were no more likely to show language delays by age two than HIV-exposed children whose mothers were not treated during pregnancy, according to a study by University of Kansas Distinguished Professor Mabel L. Rice with researchers at the National Institutes of Health (NIH) and other universities.

16 Aug 2013

Animal model of HIV sexual transmission

Infection by human immunodeficiency virus (HIV) causes acquired immunodeficiency syndrome (AIDS), a debilitating disorder in which progressive weakening of the immune system makes affected individuals more susceptible to potentially life-threatening infections and chronic diseases. Despite advances in the treatment and management of AIDS, there is no cure, and HIV infection remains a major global health problem.

16 Aug 2013

Training to caregivers can enhance lives of children born with HIV

Children born with HIV can live longer and richer lives if their caregivers receive training in ways to enhance the children's development, according to research led by Michigan State University.

16 Aug 2013

A*STAR's SIgN discovers new strategy to develop universal dengue vaccine

A new strategy that cripples the ability of the dengue virus to escape the host immune system has been discovered by A*STAR's Singapore Immunology Network. This breakthrough strategy opens a door of hope to what may become the world's first universal dengue vaccine candidate that can give full protection from all four serotypes of the dreadful virus.

14 Aug 2013

DNDi and Institut Pasteur Korea collaborates to spur fight against neglected diseases

A collaboration between the Drugs for Neglected Diseases Initiative (DNDi) and the Institut Pasteur Korea (IP-K) to spur the fight against neglected diseases has been established.

14 Aug 2013

Disease/Infection News

Study shows ART has reduced immunosuppression and viremia among PHIV youth

Second GSK intramuscular quadrivalent influenza vaccine approved by the FDA

Powerful mechanism helps viruses evade body's immune response

Mathematical model to help answer critical questions to large-scale anthrax exposure

Pre-doctoral students receive International Student Research Fellowships from HHMI

Organizations are ill prepared for e-health implementation to respond to pandemic influenza

Prion proteins responsible for Mad cow disease, Creutzfeld-Jakob disease

Scientists shed new light on molecular causes of age related degenerative disease

Research: MRSA in humans originated in cattle at least 40 years ago

New techniques for predicting severity of seasonal cholera epidemics

TSRI scientists discover molecular mechanism by which deadly Ebola virus assembles

Scientists uncover potential drug target for effective therapy against bacterial disease brucellosis

Intervention delivered through mobile phones to HIV/AIDS-positive smokers increased cessation rates

Investigators link acute viral infections to development of COPD

Probiotic does not prevent clinical relapse in patients with Crohn's disease

Children exposed to HIV in womb are no more likely to show language delays

Animal model of HIV sexual transmission

Training to caregivers can enhance lives of children born with HIV

A*STAR's SIgN discovers new strategy to develop universal dengue vaccine

DNDi and Institut Pasteur Korea collaborates to spur fight against neglected diseases

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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