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Data from Sangamo BioSciences’ SB-728-T Phase 1 clinical programs on HIV/AIDS

Sangamo BioSciences, Inc. announced that data from its Phase 1 clinical programs to develop SB-728-T, a novel therapeutic approach designed to generate a "functional cure" for HIV/AIDS, were presented at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).

11 Sep 2012

Oxyphenbutazone can kill drug resistant TB

An off-patent anti-inflammatory drug that costs around two cents for a daily dose in developing countries has been found by researchers at Weill Cornell Medical College to kill both replicating and non-replicating drug resistant tuberculosis in the laboratory -- a feat few currently approved TB drugs can do, and resistance to those is spreading.

11 Sep 2012

HIV viruses with two genetic 'footprints' associated with greater vaccine efficacy

Scientists used genetic sequencing to discover new evidence that the first vaccine shown to prevent HIV infection in people also affected the viruses in those who did become infected. Viruses with two genetic "footprints" were associated with greater vaccine efficacy. The results were published today in the online edition of the journal Nature.

10 Sep 2012

Wall Street Journal examines drug-resistant TB

The Wall Street Journal examines global efforts to stop the spread of drug-resistant tuberculosis (TB) strains, stating, "Global health officials view the emergence of incurable cases of tuberculosis in India as a worrisome evolution in a trend they have been concerned and intensely frustrated about for years -- the rise of drug resistant forms of tuberculosis around the world."

10 Sep 2012

Success and failure in fighting cholera in Haiti

"Almost two years after the deadly disease first appeared in Haiti in the aftermath of the Jan. 12, 2010 earthquake, the story of cholera is one of both success and failure," columnist Catherine Porter writes in a Toronto Star opinion piece.

10 Sep 2012

NIH awards Immunetics $3.7M SBIR contract for Babesia infection blood screening test

Immunetics, Inc., has received a $3.7 million, two year SBIR contract from the National Heart, Lung and Blood Institute, an agency of the National Institutes of Health (NIH), to support clinical trials of a new blood screening test for Babesia infection.

10 Sep 2012

Atox Bio AB103 for Necrotizing Soft Tissue Infections granted FDA Fast Track designation

Atox Bio, a clinical stage biotechnology company engaged in the development of novel immunemodulators for severe infections in critically ill patients, announced today that the U.S. Food and Drug Administration has granted Fast Track designation to AB103, its lead product, currently in development for the treatment of Necrotizing Soft Tissue Infections (NSTI).

10 Sep 2012

Study measures cost-effectiveness of on-site rapid HIV testing in drug abuse treatment programs

Less than half of community-based substance abuse treatment programs in the United States currently make HIV testing available on-site or through referral. A new study led by researchers at Weill Cornell Medical College shows the cost-effectiveness of integrating on-site rapid HIV testing into drug treatment programs.

10 Sep 2012

New oral antiseptic spray effective in killing 99.9% of infectious airborne germs

University Hospitals Case Medical Center clinical researchers will present findings about a one-two punch to prevent colds and flu in San Francisco at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) on Sept. 9.

10 Sep 2012

Dynamic mapping could potentially help fill gaps in influenza research

Influenza outbreaks in the United States typically begin with the arrival of cold weather and then spread in seasonal waves across geographic zones. But the question of why epidemics can vary from one season to the next has baffled scientists.

10 Sep 2012

Researchers, policymakers to gather at AIDS Vaccine 2012 conference in Boston

"With a completed trial in Thailand that offered evidence a vaccine could be developed to protect people from HIV, emerging science identifying antibodies against HIV, and a current trial testing a novel vaccine combination against the virus potentially producing more information in the next year, this is an exciting time to hold a conference, organizers of AIDS Vaccine 2012 say," the Center for Global Health Policy's "Science Speaks" blog reports.

7 Sep 2012

Gates foundation blog examines challenges to global TB response

"[O]ver the past month, [tuberculosis (TB)] has captured high-profile attention from the Washington Post, the New York Times, TIME, NPR, [Agence France-Presse] and other major media, generating big headlines about the rising challenge we face in tackling one of humanity's oldest and most resilient infectious diseases," Jan Gheuens, interim director of the Bill & Melinda Gates Foundation's TB Program, writes in the foundation's "Impatient Optimists" blog.

7 Sep 2012

Reuters examines challenges to implementing 'treatment as prevention,' other HIV prevention strategies in current economic climate

In an "Insight" feature article, Reuters examines how new information on the prevention benefits of HIV treatment and other strategies, such as male circumcision, "could finally break the back of the AIDS epidemic."

7 Sep 2012

Outbreak of autoimmune disease with AIDS-like symptoms in Southeast Asia

There has been an outbreak of an adult-onset immunodeficiency syndrome in Southeast Asia. The autoimmune disease causes AIDS-like symptoms but is not associated with HIV and is not contagious.

7 Sep 2012

Children and young patients with chronic HBV infection do have a protective immune response

Scientists from A*STAR's Singapore Institute for Clinical Sciences (SICS), together with clinical collaborators from London , discovered for the first time that children and young patients with chronic Hepatitis B Virus infection (HBV carriers) do have a protective immune response, contrary to current belief, and hence can be more suitable treatment candidates than previously considered.

7 Sep 2012

Washington Post examines India's efforts against TB amid fears of drug resistance

The Washington Post examines how the "discovery of an almost untreatable form of tuberculosis [TB] in India has set off alarm bells around the world and helped spur a dramatic expansion of government efforts to battle the killer lung disease."

7 Sep 2012

History of TB policy shows need for care, investment equity in developed, developing countries

In a 200th anniversary article for the New England Journal of Medicine, Salmaan Keshavjee of the Department of Global Health and Social Medicine at Harvard Medical School and Paul Farmer of Partners in Health "seek to elucidate the reasons for the anemic response to drug-resistant tuberculosis [TB] by examining the recent history of tuberculosis policy," they write.

7 Sep 2012

University of Rhode Island engineers develop new blood-testing technology

A team of engineers and students at the University of Rhode Island has developed an advanced blood-testing technology that incorporates a smartphone application, a hand-held biosensor and a credit card-sized cartridge to provide rapid, accurate biological analysis and wireless communication of test results.

7 Sep 2012

Ugandan parliamentarians threaten to hold up national budget unless more funding committed to health care

In Uganda, where "there are fewer than two health workers for every 1,000 people -- a level the World Health Organization defines as a severe shortage" -- the nation's parliamentary "social services committee, which has initial oversight of the country's health budget, pushed a resolution through parliament last week threatening to hold up approval of the entire budget unless funding to recruit and retain new health workers is increased," VOA News reports.

7 Sep 2012

Kalidex announces presentation of data on KPI-10 against MDR strains at ICAAC

Kalidex Pharmaceuticals, a privately-held anti-infective company, today announced the presentation of data on its lead development candidate KPI-10, a broad spectrum, next-generation fluoroquinolone, at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in San Francisco, September 9 through 12.

7 Sep 2012

Disease/Infection News

Data from Sangamo BioSciences’ SB-728-T Phase 1 clinical programs on HIV/AIDS

Oxyphenbutazone can kill drug resistant TB

HIV viruses with two genetic 'footprints' associated with greater vaccine efficacy

Wall Street Journal examines drug-resistant TB

Success and failure in fighting cholera in Haiti

NIH awards Immunetics $3.7M SBIR contract for Babesia infection blood screening test

Atox Bio AB103 for Necrotizing Soft Tissue Infections granted FDA Fast Track designation

Study measures cost-effectiveness of on-site rapid HIV testing in drug abuse treatment programs

New oral antiseptic spray effective in killing 99.9% of infectious airborne germs

Dynamic mapping could potentially help fill gaps in influenza research

Researchers, policymakers to gather at AIDS Vaccine 2012 conference in Boston

Gates foundation blog examines challenges to global TB response

Reuters examines challenges to implementing 'treatment as prevention,' other HIV prevention strategies in current economic climate

Outbreak of autoimmune disease with AIDS-like symptoms in Southeast Asia

Children and young patients with chronic HBV infection do have a protective immune response

Washington Post examines India's efforts against TB amid fears of drug resistance

History of TB policy shows need for care, investment equity in developed, developing countries

University of Rhode Island engineers develop new blood-testing technology

Ugandan parliamentarians threaten to hold up national budget unless more funding committed to health care

Kalidex announces presentation of data on KPI-10 against MDR strains at ICAAC

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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