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Tenofovir gel shows promise against HSV infection

HIV infection is commonly associated with other sexual infections, such as herpes simplex virus (HSV). Infection with HSV facilitates the risk of HIV infection and negatively impacts the clinical course of HIV disease. Therefore, it would be highly beneficial to identify multi-faceted microbicide compounds that are efficient against HIV-1 and other sexually transmitted infections.

20 Oct 2011

Bill, Melinda Gates speak at Malaria Forum, laud progress in fight against disease

"Eradicating malaria is not a vague, unrealistic aspiration but a tough, ambitious goal that can be reached within the next few decades," Bill Gates, co-chair of the Bill & Melinda Gates Foundation, said on Tuesday at the international Malaria Forum in Seattle, Reuters reports.

20 Oct 2011

Haiti has highest rate of cholera worldwide one year after disease outbreak began

Paul Farmer, a founder of Partners in Health (PIH) and U.N. deputy special envoy to Haiti, in an interview with the Associated Press/Washington Post "said cholera has sickened more than 450,000 people in a nation of 10 million, or nearly five percent of the population, and killed more than 6,000," giving the Caribbean nation "the highest rate of cholera in the world a mere year after the disease first arrived."

20 Oct 2011

Breakthrough in development of effective therapy against Hendra virus

A team of Federal and university scientists reports a breakthrough in the development of an effective therapy against a deadly virus, Hendra virus. The results of their study, "A Neutralizing Human Monoclonal Antibody Protects African Green Monkeys from Hendra Virus Challenge," will appear in Science Translational Medicine online.

20 Oct 2011

Winter health and safety tips

Winter is a special time for celebration. It should also be a time for added caution if you or someone in your family is an older adult. It is the season for falls, slips on icy streets, and other dangers that can be especially harmful for older adults. "Something as simple as a fall can be devastating for older men and women," says Dr. Evelyn Granieri, director of the Division of Geriatrics at NewYork-Presbyterian Hospital/The Allen Hospital. "Before the cold weather arrives, it is important to prepare."

20 Oct 2011

Despite progress in malaria vaccine development, funding remains potential stumbling block

In this Guardian opinion piece, the newspaper's health editor, Sarah Boseley, responds to the positive results of a large-scale clinical trial of an experimental malaria vaccine reported on Tuesday and recaps other strides made against the disease in recent years, writing that "there is a way to go yet, with more results from the trial to come, and many uncertainties, including how much this vaccine will cost and who will be persuaded to pay."

20 Oct 2011

Experimental vaccine halves risk of malaria in African children, results of large clinical trial suggest

"An experimental vaccine from GlaxoSmithKline halved the risk of African children getting malaria in a major clinical trial, making it likely to become the world's first shot against the deadly disease," according to a study "presented at the Bill & Melinda Gates Foundation's Malaria Forum conference in Seattle and published simultaneously in the New England Journal of Medicine" on Tuesday, Reuters reports.

20 Oct 2011

HIV advocates in Uganda 'losing faith' as country works to prevent, treat new infections, PlusNews reports

PlusNews examines how "corruption scandals, frequent treatment shortages and accusations of a misguided prevention program" have undermined progress in the fight against HIV/AIDS in Uganda, a country that had "won plaudits in the early days of the epidemic for the aggressive stance taken by President Yoweri Museveni." Uganda "lowered its HIV prevalence from 18 percent in the early 1990s to about six percent in 2000," the news service notes.

20 Oct 2011

SAIC receives NIAID contract to develop biopharmaceutical products for infectious diseases

Science Applications International Corporation (SAIC) announced today it was awarded a contract by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), to provide preclinical services for the development of biopharmaceutical products for infectious diseases.

19 Oct 2011

Link between development of new lymphoid tissue within the lung and protection against TB

New research from the Trudeau Institute may help in the ongoing fight against tuberculosis. Dr. Andrea Cooper's lab has discovered a connection between the development of new lymphoid tissue within the lung and protection against the disease.

19 Oct 2011

Cholera claims nearly 200 lives in Somalia over 24-hour period

"During the past 24 hours, cholera has claimed the lives of nearly 200 women and children in famine-stricken Somalia," a Press TV correspondent in Mogadishu reported on Sunday. "More than 800 children suffering from the disease in refugee camps were reportedly transported to medical centers in south Mogadishu," the news service writes, adding, "As the number of sick is on the rise, doctors are facing a shortage of medicine."

19 Oct 2011

Russia pledges money to support HIV, TB programs in neighboring countries

"Russia plans to step up its international role in fighting infectious disease across eastern Europe and central Asia, in what some observers see as the latest effort by the Kremlin to reassert its political influence over its former Soviet neighbors," the Financial Times reports.

19 Oct 2011

Acute HCV screening strategy for HIV-infected individuals

Researchers at The Miriam Hospital demonstrated a practical strategy for regularly screening HIV-infected patients for acute hepatitis C virus infection (HCV), a "silent epidemic" that is rising undetected in this population and can lead to serious health complications.

19 Oct 2011

Use of social media to fight malaria shows 'great promise'

As the Bill & Melinda Gates Foundation hosts the second international Malaria Forum in Seattle this week, Melinda Gates, co-chair of the Gates Foundation, in this entry in the Huffington Post's "Impact" blog reflects on the advances made in the fight against malaria since the first Malaria Forum four years ago.

19 Oct 2011

Report estimates human impact of cuts to U.S. global health spending over next five years

"Thousands of lives and years of gains made against HIV/AIDS, tuberculosis (TB) and malaria could be lost if proportional reductions are made to achieve the $1.2 trillion in spending reductions required by the Budget Control Act of 2011," according to a report issued on Monday by the Foundation for AIDS Research (amfAR), the Center for Global Health Policy's "Science Speaks" blog reports.

19 Oct 2011

Cholera outbreak in West, Central Africa accelerated by increased migration, UNICEF official says

"More than 85,000 cases of cholera in West and Central Africa are making this one of the region's most severe epidemics in recent memory," VOA News reports. "Grant Leaity, UNICEF's chief of emergency operations for West and Central Africa, says the epidemic is due, in part, to a greater movement of people across the region," VOA writes, noting, "Three simultaneous cross-border outbreaks are affecting people in two dozen countries along the coast from Guinea, and in the Lake Chad basin to the West Congo basin and around Lake Tanganyika."

19 Oct 2011

Nearly one-third of all countries affected by malaria on course to eliminate disease, WHO report says

"Nearly a third of all countries affected by malaria are on course to eliminate the mosquito-borne disease over the next 10 years, the World Health Organization (WHO) said on Monday ... in a progress report published by the Roll Back Malaria (RBM) partnership at the start of an international Malaria Forum conference in Seattle," Reuters reports.

19 Oct 2011

RTS,S vaccine reduces risk of severe malaria in African children

First results from a large-scale Phase III trial of RTS,S, published online today in the New England Journal of Medicine (NEJM), show the malaria vaccine candidate to provide young African children with significant protection against clinical and severe malaria with an acceptable safety and tolerability profile.

19 Oct 2011

Malaria elimination could be a reality soon

Malaria – a mosquito borne illness kills more than 780,000 people a year worldwide. Nearly a third of all countries affected by malaria are on course to eliminate the mosquito-borne disease over the next 10 years, the World Health Organization (WHO) said on Monday.

18 Oct 2011

First results from phase 3 malaria vaccine candidate trial

18 Oct 2011

Disease/Infection News

Tenofovir gel shows promise against HSV infection

Bill, Melinda Gates speak at Malaria Forum, laud progress in fight against disease

Haiti has highest rate of cholera worldwide one year after disease outbreak began

Breakthrough in development of effective therapy against Hendra virus

Winter health and safety tips

Despite progress in malaria vaccine development, funding remains potential stumbling block

Experimental vaccine halves risk of malaria in African children, results of large clinical trial suggest

HIV advocates in Uganda 'losing faith' as country works to prevent, treat new infections, PlusNews reports

SAIC receives NIAID contract to develop biopharmaceutical products for infectious diseases

Link between development of new lymphoid tissue within the lung and protection against TB

Cholera claims nearly 200 lives in Somalia over 24-hour period

Russia pledges money to support HIV, TB programs in neighboring countries

Acute HCV screening strategy for HIV-infected individuals

Use of social media to fight malaria shows 'great promise'

Report estimates human impact of cuts to U.S. global health spending over next five years

Cholera outbreak in West, Central Africa accelerated by increased migration, UNICEF official says

Nearly one-third of all countries affected by malaria on course to eliminate disease, WHO report says

RTS,S vaccine reduces risk of severe malaria in African children

Malaria elimination could be a reality soon

First results from phase 3 malaria vaccine candidate trial

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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