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Researchers identify a potential treatment to prevent severe COVID-19 in high-risk patients

UVA Health researchers have identified a potential treatment to prevent severe COVID-19 in patients at great risk.

15 Mar 2023

Children's immunity to COVID-19 provided by common colds

During the pandemic, it became clear that children who contracted COVID-19 became less ill than adults.

15 Mar 2023

An emerging target for chronic kidney disease treatment - DNA-PKcs

A recent Nature Communications study suggested that DNA-PKcs could be a potential target for treating chronic kidney disease.

15 Mar 2023

Lassa virus vaccine induces rapid protection in an animal model

Scientists have developed a novel Lassa vaccine using a recombinant measles virus and tested its protective efficacy against Lassa fever. A single vaccine dose has been found to induce a rapid and robust immune response in monkeys with pre-existing immunity against the measles virus.

14 Mar 2023

Vaccination protects lupus patients from contracting COVID-19

Researchers determine the risk of COVID-19 and possibility of severe sequelae in patients with systemic lupus erythematosus and the general population.

14 Mar 2023

An overview of COVID-19-associated neurological complications in children

Researchers review current literature to understand the association between COVID-19, neuroimaging, and neurological symptoms in children.

14 Mar 2023

Researchers model possible COVID-19 trajectories for 2023

Researchers model predictions of the COVID-19 pandemic trajectory under different variant and intervention scenarios.

14 Mar 2023

WHO recommends use of pyrethroid-chlorfenapyr insecticide-treated nets to prevent malaria

The World Health Organization has updated its policy regarding the type of insecticide used on bed nets to prevent malaria.

14 Mar 2023

Spike-induced humoral immunity and its association with antibody-dependent cellular cytotoxicity potency

A new study aimed to analyze the qualitative and quantitative impact of S-induced humoral immunity along with its ADCC capability in individuals who received a vaccination, recovered from an infection, or both.

14 Mar 2023

Do the symptom profiles among children with SARS-CoV-2 infection differ by variant type?

Researchers performed a comparative analysis of symptoms related to SARS-CoV-2 variants in children.

14 Mar 2023

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

Researchers investigated whether mRNA technology-based COVID-19 vaccines promote the development of autoantibodies.

14 Mar 2023

Study shows SARS-CoV-2 causes DNA damage and elicits an altered DNA damage response

Researchers assessed the association between SARS-CoV-2 infection and DNA damage and cellular senescence.

14 Mar 2023

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Researchers showed that mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) chromatin remodeling complexes represent a potential class of host-directed broad-acting SARS-CoV-2 therapeutic targets.

14 Mar 2023

Distinct microbial profile present in intrahepatic cholestasis of pregnancy patients

Researchers assessed the impact of the gut microbiome on the host's bile acid metabolism and intrahepatic cholestasis of pregnancy (ICP).

14 Mar 2023

Oral host responses to SARS-CoV-2 predict progression of COVID-19

In a recent study posted to the medRxiv* preprint server, researchers at the University of North Carolina and the National Institutes of Health determined the associations between oral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), oral antibodies against SARS-CoV-2, and coronavirus disease 2019 (COVID-19) symptoms.

14 Mar 2023

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

In a recent review published in the European Journal of Endocrinology, researchers discussed current research on the relationship between human obesity and inflammation of the hypothalamus.

14 Mar 2023

Uncovering COVID-19's impact on mental health

In a recent study published in the journal BMJ, a team of researchers from Canada and the United Kingdom conducted a systematic review of current research and meta-analysis to compare the symptoms of anxiety and depression and overall mental health among the general population before and after the onset of the coronavirus disease 2019 (COVID-19) pandemic.

14 Mar 2023

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

Researchers from The University of Texas MD Anderson Cancer Center have developed fully human bispecific antibodies, as revealed in a recent study. These antibodies can bind to two distinct epitopes of the receptor binding domain (RBD) of the SARS-CoV-2 spike protein and have demonstrated the ability to neutralize various strains of the virus, including the Omicron variant.

14 Mar 2023

The burden of Clostridioides difficile infections in the United States

Researchers review existing data on Clostridioides difficile infections among United States residents.

13 Mar 2023

Kinetics of successive SARS-CoV-2 infections

Researchers compare viral kinetics of successive SARS-CoV-2 infections.

13 Mar 2023

Disease/Infection News

Researchers identify a potential treatment to prevent severe COVID-19 in high-risk patients

Children's immunity to COVID-19 provided by common colds

An emerging target for chronic kidney disease treatment - DNA-PKcs

Lassa virus vaccine induces rapid protection in an animal model

Vaccination protects lupus patients from contracting COVID-19

An overview of COVID-19-associated neurological complications in children

Researchers model possible COVID-19 trajectories for 2023

WHO recommends use of pyrethroid-chlorfenapyr insecticide-treated nets to prevent malaria

Spike-induced humoral immunity and its association with antibody-dependent cellular cytotoxicity potency

Do the symptom profiles among children with SARS-CoV-2 infection differ by variant type?

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

Study shows SARS-CoV-2 causes DNA damage and elicits an altered DNA damage response

Researchers identify the mSWI/SNF chromatin remodeling complex as a host-directed drug target for SARS-CoV-2 infection

Distinct microbial profile present in intrahepatic cholestasis of pregnancy patients

Oral host responses to SARS-CoV-2 predict progression of COVID-19

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

Uncovering COVID-19's impact on mental health

Bispecific antibody shows improved efficacy against SARS-CoV-2 variants

The burden of Clostridioides difficile infections in the United States

Kinetics of successive SARS-CoV-2 infections

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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