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Tetravalent COVID vaccine provides broad antibody responses against SARS-CoV-2 variants in animal model

In a recent study posted to the bioRxiv* preprint server, researchers in Italy and the United States evaluated the efficacy and immunogenicity of an adjuvanted tetravalent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein subunit 1 (S1) COVID-19 vaccine.

21 Mar 2023

Prior COVID and vaccination generate superior hybrid immunity

In a recent article published in the journal Science Translational Medicine, researchers in France performed a long-term longitudinal analysis to demonstrate the benefits of hybrid immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), i.e., induced by viral infection followed by vaccination.

21 Mar 2023

Loss of smell following COVID-19 recovery: How long could it last?

In a recent study posted to the Preprints with The Lancet* server, researchers in China conducted a multi-center, retrospective study to gather data on the prevalence of olfactory dysfunction (OD) after three years of recovering from coronavirus disease 2019 (COVID-19).

21 Mar 2023

Paxlovid is 80% effective when taken within 5 days of severe COVID

In a recent study published in The Lancet’s Infectious Diseases, researchers in the United States evaluated nirmatrelvir–ritonavir treatment effectiveness against hospitalizations and deaths among coronavirus disease 2019 (COVID-19) outpatients in the United States of America (USA).

21 Mar 2023

Why are colon cancer rates in young people rising?

In a recent perspective article published in the journal Science, researchers at the Young-Onset Colorectal Cancer Center of Dana-Farber Cancer Institute emphasized that a better understanding of the etiology of early-onset colorectal cancer (EOCRC) is crucial to managing its increasing incidence worldwide

21 Mar 2023

Next-gen Mpro inhibitor: Promising new drug candidate against Omicron and other SARS-CoV-2 variants

A recent Nature Signal Transduction and Targeted Therapy journal study demonstrated the potential antiviral activity of a new Mpro inhibitor (SY110) against SARS-CoV-2 Omicron and its sublineages.

21 Mar 2023

Misleading and low-quality Mpox health information in TikTok videos

Researchers analyze TikTok videos on mpox for their content, information quality, and engagement.

21 Mar 2023

The effectiveness of mRNA vaccines during Omicron BA.4/5 predominance

Researchers evaluate vaccine effectiveness for two, three, and four doses of COVID-19 mRNA first-generation vaccines.

21 Mar 2023

Fighting antibiotic-resistant "superbugs" with viruses

The Centers for Disease Control and Prevention warns that the increase in cases of the drug-resistant bacterial infection Shigella could be a predictor of what's to come for other bacteria.

21 Mar 2023

Co-infection with MRSA ‘superbug’ could make COVID-19 outcomes even more deadly

Global data shows nearly 10 per cent of severe COVID-19 cases involve a secondary bacterial co-infection – with Staphylococcus aureus, also known as Staph A., being the most common organism responsible for co-existing infections with SARS-CoV-2.

21 Mar 2023

ACTG publishes study to simplify the administration of hepatitis C treatment

The AIDS Clinical Trials Group, the world's largest HIV research network, is announcing the publication of "Perspectives on Adherence from the ACTG 5360 MINMON Trial: A Minimum Monitoring Approach with 12 Weeks of Sofosbuvir/Velpatasvir in Chronic Hepatitis C Treatment" in the journal Clinical Infectious Diseases.

21 Mar 2023

Study suggests saliva samples may be better indicators of SARS-CoV-2 persistence than nasal swabs

In a recent study published in the PLOS ONE journal, researchers at Rutgers New Jersey Medical School explored the persistence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in human saliva.

21 Mar 2023

Study provides insights on stability of SARS-CoV-2 in biological fluids of animals

In a recent study published in the Viruses journal, researchers assessed the stability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among biological fluids found in animals.

21 Mar 2023

Discovery of 16th century coronavirus in France

In a recent study published in the International Journal of Infectious Diseases, researchers conducted paleoserological tests on dental pulp samples of skeletons excavated from the Abbey Saint-Pierre in the village of Baume-Les-Messieurs in France.

20 Mar 2023

Research reports spillover of highly pathogenic avian influenza A(H5N1) into marine mammals in the northeastern United States

A recent study published in the United States (U.S.) Centers for Disease Control and Prevention (CDC) journal Emerging Infectious Diseases reported the outbreak of the highly pathogenic hemagglutinin type 5 and neuraminidase type 1 (H5N1) avian influenza virus among New England gray and harbor seals in the United States (U.S.)

20 Mar 2023

Elevated mucosal immune response expedites COVID-19 recovery

Researchers examine the role of inflammatory mediator expression networks on clinical outcomes in individuals with high/low SARS-CoV-2 burden.

20 Mar 2023

RSV causes 160,000 hospitalizations every year in the EU, according to new study

Researchers estimate hospitalizations associated with respiratory syncytial virus infection in the European Union.

20 Mar 2023

The impact of long-COVID on professional soccer

Researchers assess the duration of long COVID and its impact on soccer players.

20 Mar 2023

SARS-CoV-2 infection damages the CD8+ T cell response to vaccination

The magnitude and quality of a key immune cell's response to vaccination with two doses of the Pfizer-BioNTech COVID-19 vaccine were considerably lower in people with prior SARS-CoV-2 infection compared to people without prior infection, a study has found.

20 Mar 2023