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GSK decides to remove potentially hazardous zinc from denture adhesive products

GlaxoSmithKline, the maker of popular denture adhesives Poligrip and Super Poligrip, announced today that it will remove zinc from all of its denture adhesive products. The pharmaceutical giant has added the potentially hazardous mineral to its adhesives for decades, despite overwhelming evidence that consuming large quantities of zinc over an extended period of time can cause serious neurological damage.

19 Feb 2010

UCSF, Genentech partner to discover and develop drug candidates for neurodegenerative diseases

The University of California, San Francisco has signed a partnership agreement with Genentech, Inc., a wholly owned member of the Roche Group, to discover and develop drug candidates for neurodegenerative diseases.

19 Feb 2010

Unusual compounds in pitcher plant could prove effective against human fungal infections

The moment insects like flies, ants and beetles fall into a pitcher, the plant's enzymes are activated and begin dissolving their new meal, obtaining nutrients such as carbon and nitrogen which are difficult to extract from certain soils.

19 Feb 2010

Walker's book focuses on deaths, genetic deformities and other health issues resulting from environmental pollution

Since the brain-injuring virus needs mosquitoes and pigs to spread, government officials should ban standing water in cemetery cisterns and urban drainage ditches. They should keep industrial "piggeries" away from cities and their populations.

19 Feb 2010

Poor prescription practices among doctors may increase antibiotic resistance

A new paper in the February 17th edition of the journal Molecular Cell describes how exposure to low levels of antibiotics increases mutations in E. coli and Staphylococcus bacteria hundreds of times more than normal, making the creation of drug-resistant strains more likely.

19 Feb 2010

WHO recommends H1N1 be added to next year's seasonal flu virus

The WHO is recommending the H1N1 (swine flu) virus be added to the regular flu vaccine for the Northern Hemisphere's 2010-2011 regular flu season, the Associated Press reports (2/18).

19 Feb 2010

GeoVax Labs presents results of preclinical study on prototype HIV/AIDS vaccine at CROI

GeoVax Labs, Inc., an Atlanta-based, biopharmaceutical company developing vaccines for diseases caused by HIV-1 (Human Immunodeficiency Virus), today announced that it presented the results of a preclinical study on a prototype HIV/AIDS vaccine at the Conference on Retroviruses and Opportunistic Infections (CROI) in San Francisco.

18 Feb 2010

Acute sinus infections always begin as cold

Have a cold that just won't go away or is getting worse? Chances are your cold has developed into a sinus infection - a common problem this time of year, says Alan Wild, M.D., assistant professor of otolaryngology at Saint Louis University School of Medicine.

18 Feb 2010

Travellers are likely to become increasingly exposed to canecutter's disease: Study

A team led by PhD researcher Dr Colleen Lau from the School of Population Health http://www.sph.uq.edu.au/ , has discovered the disease, known medically as leptospirosis, was traditionally a concern for males working in the agricultural and livestock industries, as it is contracted from contact with the urine of host animals.

18 Feb 2010

PK/PD data demonstrates clear relationship between TBR-652 plasma concentrations and antiviral activity

Pharmacokinetic/pharmacodynamic (PK/PD) data for TBR-652, which is being developed by Tobira Therapeutics for the treatment of HIV infection, show a strong relationship between drug exposure and viral suppression with this next-generation CCR5 receptor antagonist. These data were presented here today at the 17th Conference on Retroviruses and Opportunistic Infections (CROI).

18 Feb 2010

UCSF receives $1.15M grant to integrate family planning into HIV treatment and care

UCSF has received a $1.15 million grant from the Bill & Melinda Gates Foundation to determine if integrating family planning into HIV treatment and care will increase contraceptive use and decrease unintended pregnancy among HIV-positive women. UCSF will partner with the Kenya Medical Research Institute and Ibis Reproductive Health to conduct the research.

18 Feb 2010

Signaling protein has key role in fighting bacterial infection and inflammation in intestinal tract: Study

A signaling protein that is key in orchestrating the body's overall immune response has an important localized role in fighting bacterial infection and inflammation in the intestinal tract, according to a study by UC San Diego School of Medicine investigators, published in the journal Cell Host and Microbe.

18 Feb 2010

Gilead Sciences’ “Quad” regimen for HIV exhibits antiretroviral activity comparable to Atripla

Gilead Sciences, Inc. announced Phase II clinical trial results today showing that its investigational fixed-dose single-tablet “Quad” regimen of elvitegravir, GS 9350 (cobicistat) and Truvada® (emtricitabine and tenofovir disoproxil fumarate) for the treatment of HIV infection exhibited antiretroviral activity comparable to that of Atripla® (efavirenz 600 mg/ emtricitabine 200 mg/ tenofovir disoproxil fumarate 300 mg).

18 Feb 2010

HPV DNA testing vital in identification of cervical cancer

Roche Molecular Systems, Inc. announced today that preliminary data from its ATHENA (Addressing THE Need for Advanced HPV Diagnostics) trial support the importance of screening for human papillomavirus (HPV) genotypes that put women at highest risk for developing cervical cancer. ATHENA is a prospective, double-blind, multi-centered, 47,000-patient, U.S.-registration trial designed to demonstrate the effectiveness of HPV detection as part of a cervical cancer screening program.

18 Feb 2010

Phase 3b ODIN study of once-daily PREZISTA in HIV-1 adults presented at CROI 2010

In a new study of treatment-experienced HIV-1-infected adults with no PREZISTA® (darunavir) resistance-associated mutations (RAMs), 72 percent of patients in the PREZISTA/ritonavir (r) (800/100 mg) once-daily arm achieved undetectable viral loads (<50 copies/mL) compared with 71 percent of patients in the PREZISTA/r (600/100 mg) twice-daily arm. The study met its primary objective of non-inferiority. These data from the Phase 3b ODIN study were presented today at CROI 2010, the 17th Conference on Retroviruses and Opportunistic Infections, in San Francisco.

18 Feb 2010

Changes in vaginal pH make women more susceptible to infections

Changes in vaginal pH as a result of common “pH triggers” make women more susceptible to infections such as bacterial vaginosis (BV). Understanding how the vaginal environment responds to pH fluctuation helps health professionals prevent and treat these conditions.

18 Feb 2010

Study demonstrates once-a-week TB drug is as effective as daily dose

Researchers at the Council for Scientific and Industrial Research (CSIR) are one step closer to providing Tuberculosis (TB) sufferers with a once-a-week medicinal regime rather than their current daily doses.

18 Feb 2010

Healthy immune response depends on TRPV2 protein

If bad bacteria lurk in your system, chances are they will bump into the immune system's protective cells whose job is gobbling germs.

18 Feb 2010

Viral infection can suppress immune response to secondary bacterial infection

A new study reveals how infection with the influenza virus impacts the way that the immune system responds to subsequent infections. The research, published by Cell Press in the February 18th issue of the journal Cell Host and Microbe, provides a new understanding of the physiological and pathological consequences of the flu.

18 Feb 2010

Gene study could pave way for novel methods for plagues and other infectious diseases

An international consortium of scientists, including Universitat Aut-noma de Barcelona (UAB) researcher Deodoro Oliveira, have sequenced the genome of three species of parasitoid wasps of the genus Nasonia.

18 Feb 2010

Disease/Infection News

GSK decides to remove potentially hazardous zinc from denture adhesive products

UCSF, Genentech partner to discover and develop drug candidates for neurodegenerative diseases

Unusual compounds in pitcher plant could prove effective against human fungal infections

Walker's book focuses on deaths, genetic deformities and other health issues resulting from environmental pollution

Poor prescription practices among doctors may increase antibiotic resistance

WHO recommends H1N1 be added to next year's seasonal flu virus

GeoVax Labs presents results of preclinical study on prototype HIV/AIDS vaccine at CROI

Acute sinus infections always begin as cold

Travellers are likely to become increasingly exposed to canecutter's disease: Study

PK/PD data demonstrates clear relationship between TBR-652 plasma concentrations and antiviral activity

UCSF receives $1.15M grant to integrate family planning into HIV treatment and care

Signaling protein has key role in fighting bacterial infection and inflammation in intestinal tract: Study

Gilead Sciences’ “Quad” regimen for HIV exhibits antiretroviral activity comparable to Atripla

HPV DNA testing vital in identification of cervical cancer

Phase 3b ODIN study of once-daily PREZISTA in HIV-1 adults presented at CROI 2010

Changes in vaginal pH make women more susceptible to infections

Study demonstrates once-a-week TB drug is as effective as daily dose

Healthy immune response depends on TRPV2 protein

Viral infection can suppress immune response to secondary bacterial infection

Gene study could pave way for novel methods for plagues and other infectious diseases

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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