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Also in global health news: Infant, maternal mortality in N. Korea; malaria in Cambodia; Zambia PEPFAR program; Pakistan's anti-polio campaign; U.N. Ambassador responds to Somalia; Myanmar refugees

Higher rates of infant and maternal mortality have lead to a decline of life expectancy in North Korea over the past 15 years, census figures, which were obtained with help form the U.N. Population Fund, said on Monday, Agence France-Presse reports (2/22).

23 Feb 2010

Hospital-acquired infections increase mortality rate and healthcare costs

Two common conditions caused by hospital-acquired infections (HAIs) killed 48,000 people and ramped up health care costs by $8.1 billion in 2006 alone, according to a study released today in the Archives of Internal Medicine.

23 Feb 2010

News outlets examine use of ART, microbicide development presented at conference

News outlets continue to report on the science discussed at the Conference on Retroviruses and Opportunistic Infections (CROI), which ended Friday in San Francisco.

23 Feb 2010

Research reveals human Chlamydia pneumoniae has originated from animal source

Animals have been found to have infected humans sometime in the past with the common respiratory disease Chlamydia pneumoniae, according to Queensland University of Technology infectious disease expert Professor Peter Timms.

23 Feb 2010

PositiveID, RECEPTORS announce successful completion of rapid virus detection system Phase I development

PositiveID Corporation, in conjunction with its development partner RECEPTORS LLC, announced today that it has successfully completed Phase I development of its rapid virus detection system, a non-invasive, point-of-care test to test patient samples and identify various forms of influenza within minutes. Phase II of the development, which the Company expects to complete by the end of 2010, is planned to launch in February 2010.

23 Feb 2010

Haitian President says up to 300,000 people could have died in quake

The major earthquake in January in Haiti could have killed as many as 300,000 people, an estimate that includes bodies buried in the rubble, Haitian President Rene Preval said on Sunday at a meeting of Latin American and Caribbean leaders in Mexico, Reuters reports.

23 Feb 2010

NIH awards Sanaria Phase II SBIR grant to develop genetically attenuated, whole parasite malaria vaccine

Sanaria Inc. has received additional support from the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health in the form of a Phase II Small Business Innovation Research (SBIR) Grant. The three-year award totaling approximately $3 million will support collaborative research by investigators at Sanaria and Columbia University.

23 Feb 2010

Gene study provides new clues to fight infections

Investigators at The Methodist Hospital Research Institute in Houston examined for the first time the long-term response to strep throat on a genome-wide level, shedding light on how group A streptococcus interacts with the patient's immune system and attempts to circumvent it.

23 Feb 2010

Medical test for aging adults could be helpful in determining infants’ intestinal conditions

A medical test initially researched for aging adults also could be helpful for premature babies, according to scientists with Texas AgriLife Research.

23 Feb 2010

UCI researchers create new breed of flightless mosquitoes for dengue control

UCI researchers and colleagues from Oxitec Ltd. and the University of Oxford created the new breed. Flightless females are expected to die quickly in the wild, curtailing the number of mosquitoes and reducing - or even eliminating - dengue transmission. Males of the strain can fly but do not bite or convey disease.

23 Feb 2010

Global rules barring TB patients from flying are too stringent, study says

A "controversial" study, released on Sunday, "suggests international rules that bar potentially infectious tuberculosis patients from flying are too stringent and airline passengers are really at little risk from catching TB from a fellow traveler," the Associated Press/Washington Post reports. The paper is being published in the March edition of Lancet Infectious Diseases (Stobbe, 2/21).

23 Feb 2010

AAAS meeting examines test-and-treat model's potential for fighting HIV spread, TB co-infection

Researchers speaking at the American Association for the Advancement of Science (AAAS) meeting on Saturday, discussed how a strategy to promote universal voluntary HIV tests and early antiretroviral treatment for patients living in high-risk areas might "derail the spread of [HIV/]AIDS, a battle where a successful vaccine remains elusive," the Associated Press/Washington Post reports

23 Feb 2010

NHMRC awards $12.7 million for malaria research

A research program that aims to better understand malaria infection and develop treatments and vaccines for the disease has today been awarded $12.7 million (US$11.5 million) by Australia's National Health and Medical Research Council (NHMRC).

22 Feb 2010

Alnylam Pharmaceuticals initiates ALN-RSV01 Phase IIb trial in adult lung transplant patients for RSV infection

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has initiated a Phase IIb trial in adult lung transplant patients with ALN-RSV01, an RNAi therapeutic for the treatment of respiratory syncytial virus (RSV) infection. RSV infection in lung transplant patients represents an important unmet medical need; the condition is associated with significant morbidity, including the development of acute lung transplant rejection in 10% to 20% of infected patients.

22 Feb 2010

HHS Secretary reviews H1N1 response at NACCHO conference

Thank you, Tom. I also want to thank NACCHO for hosting this important conference and for inviting me to speak here today. Public health is a top priority for this administration. So is strengthening our partnerships across government. So I’m glad I could come talk with you about how we can work together to keep Americans healthy and safe.

22 Feb 2010

Researchers based in Africa have more comprehensive understanding of malaria: MIM

Organisations supporting medical research in Africa, for example research on malaria, cannot assume that scientific results are independent of time and space. Instead the results reflect the interplay between the research environment, researchers and the study object. This is the result of a dissertation in Theory of Science from the University of Gothenburg, Sweden.

22 Feb 2010

Tony Blair participates in the work of Muslim-Christian alliance in Africa led by NIFAA

This afternoon Tony Blair participated in the work of the largest Muslim-Christian alliance in Africa led by the Nigerian Inter-Faith Action Association (NIFAA), with funding support from the Nigerian government, the World Bank, the Center for Interfaith Action on Global Poverty (CIFA), and other international funders.

22 Feb 2010

ASU epidemiologist to take close look at factors impacting influenza dynamics within Mexico

Influenza surveillance mechanisms in Mexico were adequate during the fast-spreading H1N1 outbreak in 2009, yet Mexico did not have the infrastructure to quickly identify the emergence of this novel strain, according to an Arizona State University (ASU) epidemiologist.

21 Feb 2010

Bleeding after percutaneous biopsy rare

Even among patients who have taken aspirin in proximity to an image-guided percutaneous biopsy, risk of major bleeding associated with the procedure is low, according to a study in the March issue of the American Journal of Roentgenology (www.ajronline.org). Image-guided percutaneous biopsies are an important means of diagnosing disease in organs and other soft tissues. They involve the removal of cells or tissues for examination.

20 Feb 2010

Recent releases in Global Health

The Infectious Diseases Center for Global Health Policy's "Science Speaks" blog examines U.S. Global AIDS Coordinator Eric Goosby's recent address to the Conference on Retroviruses and Opportunistic Infections (CROI) where he reemphasized the Obama administration's commitment to "'maintaining, extending and increasing' the U.S. response to global AIDS." Goosby reflected on the lessons drawn from PEPFAR to date and presented components of the 5-year PEPFAR strategy, the blog notes.

20 Feb 2010

Disease/Infection News

Also in global health news: Infant, maternal mortality in N. Korea; malaria in Cambodia; Zambia PEPFAR program; Pakistan's anti-polio campaign; U.N. Ambassador responds to Somalia; Myanmar refugees

Hospital-acquired infections increase mortality rate and healthcare costs

News outlets examine use of ART, microbicide development presented at conference

Research reveals human Chlamydia pneumoniae has originated from animal source

PositiveID, RECEPTORS announce successful completion of rapid virus detection system Phase I development

Haitian President says up to 300,000 people could have died in quake

NIH awards Sanaria Phase II SBIR grant to develop genetically attenuated, whole parasite malaria vaccine

Gene study provides new clues to fight infections

Medical test for aging adults could be helpful in determining infants’ intestinal conditions

UCI researchers create new breed of flightless mosquitoes for dengue control

Global rules barring TB patients from flying are too stringent, study says

AAAS meeting examines test-and-treat model's potential for fighting HIV spread, TB co-infection

NHMRC awards $12.7 million for malaria research

Alnylam Pharmaceuticals initiates ALN-RSV01 Phase IIb trial in adult lung transplant patients for RSV infection

HHS Secretary reviews H1N1 response at NACCHO conference

Researchers based in Africa have more comprehensive understanding of malaria: MIM

Tony Blair participates in the work of Muslim-Christian alliance in Africa led by NIFAA

ASU epidemiologist to take close look at factors impacting influenza dynamics within Mexico

Bleeding after percutaneous biopsy rare

Recent releases in Global Health

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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