Disease/Infection News

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Urine LAM-ELISA's sensitivity of 50.7% in identifying TB disappoints

Urine LAM-ELISA does not appear to be useful as an independent diagnostic test for pulmonary tuberculosis (TB). A trial of the new diagnostic, described in the open access journal BMC Infectious Diseases found that it was only capable of identifying 50.7% of TB cases.

28 Aug 2009

TRAF6 protein can activate a cell signalling molecule associated with cancer

The mainstay immune system protein TRAF6 plays an unexpected, key role activating a cell signaling molecule that in mutant form is associated with cancer growth, researchers at The University of Texas M. D. Anderson Cancer Center report in the Aug. 28 edition of Science.

28 Aug 2009

Caucasians have a higher rate of HBV recurrence compared to Asian Americans and African Americans

According to the Centers for Disease Control and Prevention (CDC) 1.5 to 2 million Americans are infected with the hepatitis B virus (HBV). Prior studies have shown there to be significant racial differences in access to and outcomes of liver transplantation. Recently, doctors from across the U.S. conducted a multicenter retrospective-prospective study of the waitlist status and outcomes of liver transplant patients with HBV infection.

28 Aug 2009

Elorac offers Zithranol-RR for treating plaque psoriasis

Now patients with mild to moderate plaque psoriasis have a new topical treatment option available by prescription. Zithranol™-RR (anthralin rapid release microcrystalline encapsulated cream, 1.2%), is an innovative topical therapy for plaque psoriasis according to Elorac, Inc., a privately held emerging dermatology company. Zithranol™-RR provides an advanced delivery system for anthralin achieving long remission times with no long-term side effects in a steroid-free, silky cream.

28 Aug 2009

Infectious Disease Research Institute commences clinical trial of its leishmaniasis vaccine in Sudan

IDRI (Infectious Disease Research Institute) announced today the start of a clinical trial in Sudan to test its leishmaniasis vaccine candidate for the treatment of post kala-azar dermal leishmaniasis (PKDL), a complication of visceral leishmaniasis (VL) which is observed in 50% of patients treated for VL in the country, predominantly affecting children.

28 Aug 2009

NIMH grants Xhale $1.7 million to develop the SMART medication adherence system for HIV/AIDS therapies

Xhale, Inc. has been awarded a $1.7 million Small Business Innovation Research (SBIR) Phase II grant by the NIH National Institute of Mental Health (NIMH) to continue the development of SMART (Self Monitoring and Reporting Therapeutics), a breath-based medication adherence system for HIV/AIDS therapies.

28 Aug 2009

Maxim Health Systems' website provides detailed information about flu vaccination

Maxim's dedicated flu Web site provides detailed information about the flu vaccination and allows consumers to locate seasonal flu clinics in their area by searching by zip code. In addition, Maxim is preparing to launch several new online resources for consumers to protect themselves and their families this flu season.

28 Aug 2009

Chk1 and Fbx6 play an important role for the regulation of response to chemotherapy

Cell cycle checkpoints act like molecular tripwires for damaged cells, forcing them to pause and take stock. Leave the tripwire in place for too long, though, and cancer cells will press on regardless, making them resistant to the lethal effects of certain types of chemotherapy, according to researchers at the Salk Institute for Biological Studies.

28 Aug 2009

Also in global health news: NTD study; false cholera cases in Zimbabwe; contaminated water in Kenya; doctor's strike ends

UPI reports on a recent review article in the journal PLoS Neglected Tropical Diseases that analyzed the toll of neglected tropical diseases on populations in sub-Saharan Africa. "Researchers said helminth (parasitic worm) infections account for approximately 85 percent of the neglected tropical diseases, which overall might be equivalent to more than double that caused by tuberculosis and as much as half of the area's malaria disease burden," the news service writes (8/26).

28 Aug 2009

Brazil emerges as country with highest number of H1N1-related deaths

The H1N1 (swine) flu is blamed for 557 deaths in Brazil, "making it the country with the highest number of fatalities in the world from the disease," according to the country's health ministry, Agence France-Presse reports. "Brazil's health ministry said in a statement the government was freeing up one billion dollars to buy 73 million doses of a new vaccine being developed against swine flu, as well as Tamiflu stocks, hospital equipment and diagnostic gear," the news service writes (8/26).

28 Aug 2009

H1N1 virus detected in turkeys

The detection of an H1N1 virus in turkeys in Chile raises concern that poultry farms elsewhere in the world could also become infected with the pandemic flu virus currently circulating in humans, FAO said today.

27 Aug 2009

Movember to present at the LIVESTRONG Global Cancer Summit

Staggering statistic: cancer kills more people every year than AIDS, tuberculosis and malaria combined. Joining more than 250 advocates from around the world, Adam Garone, co-founder and CEO of Movember, the world's largest charity for men's health, will present at the LIVESTRONG Global Cancer Summit in Dublin, Ireland, August 24 - 26.

27 Aug 2009

EDCTP welcomes proposals for tuberculosis vaccines and HIV/AIDS treatment projects

EDCTP welcomes project proposals as a response to the following calls: Tuberculosis vaccines, HIV/AIDS treatment and Member States Initiated projects.

27 Aug 2009

BMSN and ENTB collaborate with Therinjectto to develop a new immuno-therapeutic cancer vaccine

Bio-Matrix Scientific Group, Inc. and Its majority owned subsidiary Entest BioMedical Inc. announced today they have finalized a definitive agreement with Therinject LLC for the development of a new immuno-therapeutic cancer vaccine. Therinject LLC is engaged in the development of cancer treatments utilizing immunology based approaches.

27 Aug 2009

Aid agencies seek to access displaced Yemenis at 'high risk' of disease outbreaks

Aid agencies on Tuesday "appealed for better access" to "tens of thousands" of people in Yemen who have been displaced by violence and are facing "a high risk of outbreaks of malaria and diarrhoeal diseases among the already malnourished population," Reuters reports.

27 Aug 2009

HHS webcast to discuss how pregnant women and new mothers can prepare for the H1N1 flu

The U.S. Department of Health and Human Services (HHS) will host a Webcast to discuss how pregnant women and new mothers can prepare for the H1N1 flu on Thursday, August 27th.

27 Aug 2009

Relationship between the CD14 variation and the formation of portal lymphoid aggregates discovered

It is still unknown why the natural history of chronic disease caused by hepatitis C virus (HCV), which currently infects 3% of the world's population, varies from mild in some patients to rapidly progressing in others. Age, sex, alcohol consumption and liver sensitivity to gut-derived bacterial endotoxins, were the early factors defined to enhance the risk of fibrosis progression.

27 Aug 2009

US Department of Health funds a project to enhance the quality of care to women of color suffering from HIV/AIDS

Dr. S. Vincent Grasso, a member of the Stevens Healthcare Information Technology Management Advisory Board and Seminar Leader for the Stevens Healthcare Educational Partnership (SHEP), will act as technical lead, solution provider and systems integrator within a nation-wide initiative to enhance the quality of care to women of color suffering from HIV/AIDS. The US Department of Health and Human Services is the funding agency for the project, which will be implemented in urban centers across America.

27 Aug 2009

Invasive front dominant expression of LNγ2 and LNβ3 and active MMP7 play a key role in biliary tract cancer

Despite recent advances in diagnosis and treatment, the prognosis of patients with biliary tract cancer is still poor. Elucidating the biological characteristics of these carcinomas has become necessary to improve the prognosis of patients and to devise better treatment strategies. A recent study report that invasive front dominant expression of LNγ2 and LNβ3 and active MMP7 play a key role in the progression of biliary tract cancer.

26 Aug 2009

Researchers reveal that genes contributing to drug resistance in NSCLC disease could be predicted

The genes that may contribute to drug resistance in non-small cell lung cancer (NSCLC) can be predicted. Researchers writing in the open access journal BMC Cancer found good correlation between genes believed to be involved in drug sensitivity and resistance and actual in vitro chemosensitivity.

26 Aug 2009

Disease/Infection News

Urine LAM-ELISA's sensitivity of 50.7% in identifying TB disappoints

TRAF6 protein can activate a cell signalling molecule associated with cancer

Caucasians have a higher rate of HBV recurrence compared to Asian Americans and African Americans

Elorac offers Zithranol-RR for treating plaque psoriasis

Infectious Disease Research Institute commences clinical trial of its leishmaniasis vaccine in Sudan

NIMH grants Xhale $1.7 million to develop the SMART medication adherence system for HIV/AIDS therapies

Maxim Health Systems' website provides detailed information about flu vaccination

Chk1 and Fbx6 play an important role for the regulation of response to chemotherapy

Also in global health news: NTD study; false cholera cases in Zimbabwe; contaminated water in Kenya; doctor's strike ends

Brazil emerges as country with highest number of H1N1-related deaths

H1N1 virus detected in turkeys

Movember to present at the LIVESTRONG Global Cancer Summit

EDCTP welcomes proposals for tuberculosis vaccines and HIV/AIDS treatment projects

BMSN and ENTB collaborate with Therinjectto to develop a new immuno-therapeutic cancer vaccine

Aid agencies seek to access displaced Yemenis at 'high risk' of disease outbreaks

HHS webcast to discuss how pregnant women and new mothers can prepare for the H1N1 flu

Relationship between the CD14 variation and the formation of portal lymphoid aggregates discovered

US Department of Health funds a project to enhance the quality of care to women of color suffering from HIV/AIDS

Invasive front dominant expression of LNγ2 and LNβ3 and active MMP7 play a key role in biliary tract cancer

Researchers reveal that genes contributing to drug resistance in NSCLC disease could be predicted

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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