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Mutations associated with prion diseases are sufficient to cause transmissible neurodegenerative disease

For the first time, Whitehead Institute researchers have shown definitively that mutations associated with prion diseases are sufficient to cause a transmissible neurodegenerative disease.

26 Aug 2009

Viral polymerase may provide a new therapeutic target for host-adapted avian influenza

Current research suggests that viral polymerase may provide a new therapeutic target for host-adapted avian influenza. The related report by Gabriel et al, "Spread of Infection and Lymphocyte Depletion in Mice Depends on Polymerase of Influenza Virus" appears in the September 2009 issue of the American Journal of Pathology.

26 Aug 2009

Asia will experience H1N1 vaccine shortage, WHO says

A spokesperson for the WHO said on Tuesday that Asia will not have enough H1N1 vaccines for swine flu when cold weather hits, Reuters reports.

26 Aug 2009

Anti-glycan antibody positivity observed in celiac disease

Anti-microbial antibody formation has been reported in celiac disease. Relatively high positivity rates were observed for the conventional antibodies, for example, ASCA, anti-OmpW, and anti-I2, and they were known to decrease after a successful gluten free-diet. The importance of newly discovered inflammatory bowel disease-associated antibodies (including anti-glycan antibodies and anti-OMP) in celiac disease is not sure.

26 Aug 2009

The American Brain Tumor Association to pursue increased funding of brain tumor research in Senator Kennedy's memory

The following is a statement by Elizabeth Wilson, Executive Director, American Brain Tumor Association on the death of U.S. Senator Edward M. Kennedy: "Senator Kennedy's brain tumor diagnosis just over a year ago brought international attention to this dreadful and devastating disease. He will be remembered as a tireless health care advocate who displayed courage and strength in his final battle against an unrelenting illness.

26 Aug 2009

Patient health and safety survey reveals that healthcare facilities are not ready to combat swine flu pandemic

A patient health and safety survey of 190 American hospitals from coast to coast compiled by registered nurses in eight different states finds that a disturbing number of our nation's healthcare facilities are not prepared for the coming H1N1/swine flu pandemic, according to results released today by the California Nurses Association/National Nurses Organizing Committee.

26 Aug 2009

DAS181 inhibits H5N1 Influenza lung virus infection of human lung tissues

NexBio, Inc. announced today the publication "DAS181 Inhibits H5N1 Influenza Lung Virus Infection of Human Lung Tissues" in the September, 2009 issue of the journal Antimicrobial Agents and Chemotherapy (AAC).

26 Aug 2009

Sebelius names Chair of Presidential Advisory Council on HIV/AIDS

HHS Secretary Kathleen Sebelius on Monday named Helene Gayle, president and chief executive of the charity CARE USA, as the chair the Presidential Advisory Council on HIV/AIDS, Reuters reports.

26 Aug 2009

Research study concludes the difference in mortality between men and women depending on the type of ACS

A new study from NYU School of Medicine found that women may have a slightly higher risk of death than men in the thirty days following an acute coronary syndrome (ACS), but that these differences appear to be attributable to factors such as severity and type of ACS.

26 Aug 2009

MRSA Survivors Network founder organizes the first Inaugural World MRSA Day

MRSA Survivors Network founder, Jeanine Thomas has organized the first Inaugural World MRSA Day Kick-off event on October 1st in Chicago at Loyola University. Other events will be held across the globe and in the U.S. on October 2nd and throughout the month of October, World MRSA Awareness Month.

26 Aug 2009

Smokers twice as likely to get active TB, study finds

"A study in Taiwan has found that smokers are twice as likely to develop active tuberculosis compared to people who have never smoked, prompting calls for policymakers to be tougher on smoking," Reuters reports (Lyn, 8/24).

26 Aug 2009

Symptomless blood disorder MGUS not a precursor of serious diseases

A symptomless blood disorder, monoclonal gammopathy of undetermined significance, known as MGUS, is not linked to as many serious diseases as previously thought. This finding may save patients from undergoing unnecessary workup and treatment according to a study published in the August 2009 issue of Mayo Clinic Proceedings.

26 Aug 2009

Australian researchers to discover proteins that cause multiple sclerosis

Australian researchers will aim to discover the proteins that cause multiple sclerosis (MS), thanks to a new nationwide research effort. The new research project will receive funding of $1 million over four years, starting this year, under the Australian Research Council's Linkage Projects funding scheme and from MS Research Australia (MSRA), the research arm of MS Australia.

26 Aug 2009

Duodenal obstruction observed after selective transcatheter arterial embolization for a duodenal diverticular hemorrhage

Ho Jeong and his colleague from Korea presented a case of duodenal obstruction after successful selective transcatheter arterial embolization (TAE) for a duodenal diverticular hemorrhage. Their study will be published on August 14, 2009 in the World Journal of Gastroenterology.

26 Aug 2009

Profectus BioSciences to conduct proof-of-concept studies with its rVSV vector technology

Profectus BioSciences, Inc. (Profectus), a clinical stage biopharmaceutical company focused on the development of novel vaccine candidates for serious chronic infections, announced today it has entered into a research collaboration agreement with the PATH Malaria Vaccine Initiative (MVI) to conduct proof-of-concept studies with its proprietary, recombinant vesicular stomatitis virus (rVSV) vector technology as a preventative malaria vaccine.

26 Aug 2009

MicroRNAs in saliva could aid in the detection of oral cancer

Researchers continue to add to the diagnostic alphabet of saliva by identifying the presence of at least 50 microRNAs that could aid in the detection of oral cancer, according to a report in Clinical Cancer Research, a journal of the American Association for Cancer Research.

26 Aug 2009

Study suggests that connective tissue growth factor plays a vital role in liver fibrosis progression

Accumulating evidence suggests that connective tissue growth factor (CCN2) plays a central role in fibrotic conditions in many organ systems. Fibrosis is a scarring condition that is characterized by excessive collagen production that impedes normal cell function and can cause organ dysfunction and failure.

25 Aug 2009

University of Manchester researchers discover kinase inhibitors for treating early-stage cancers

University of Manchester researchers found that a special type of the chemicals known as 'kinase inhibitors' opened up communication channels on the surface of cells that enabled healthy cells to 'talk' to the cancer cells.

From The University of Manchester 25 Aug 2009

LAF report estimates the total economic burden of new cancer cases at $305 billion in 2009

A landmark report released today by the Lance Armstrong Foundation (LAF) estimates the total economic burden of new cancer cases at $305 billion in 2009. The findings are included in the report, "Breakaway: The Global Burden of Cancer - Challenges and Opportunities," released today in Dublin at the premiere LIVESTRONG Global Cancer Summit.

25 Aug 2009

TIME examines discrimination against HIV-positive children in Vietnam

TIME examines the discriminatory efforts to keep Vietnamese children living with HIV out of the country's public schools even though, by law, "[c]hildren cannot be barred from school because they or any of their family members have HIV/AIDS."

25 Aug 2009

Disease/Infection News

Mutations associated with prion diseases are sufficient to cause transmissible neurodegenerative disease

Viral polymerase may provide a new therapeutic target for host-adapted avian influenza

Asia will experience H1N1 vaccine shortage, WHO says

Anti-glycan antibody positivity observed in celiac disease

The American Brain Tumor Association to pursue increased funding of brain tumor research in Senator Kennedy's memory

Patient health and safety survey reveals that healthcare facilities are not ready to combat swine flu pandemic

DAS181 inhibits H5N1 Influenza lung virus infection of human lung tissues

Sebelius names Chair of Presidential Advisory Council on HIV/AIDS

Research study concludes the difference in mortality between men and women depending on the type of ACS

MRSA Survivors Network founder organizes the first Inaugural World MRSA Day

Smokers twice as likely to get active TB, study finds

Symptomless blood disorder MGUS not a precursor of serious diseases

Australian researchers to discover proteins that cause multiple sclerosis

Duodenal obstruction observed after selective transcatheter arterial embolization for a duodenal diverticular hemorrhage

Profectus BioSciences to conduct proof-of-concept studies with its rVSV vector technology

MicroRNAs in saliva could aid in the detection of oral cancer

Study suggests that connective tissue growth factor plays a vital role in liver fibrosis progression

University of Manchester researchers discover kinase inhibitors for treating early-stage cancers

LAF report estimates the total economic burden of new cancer cases at $305 billion in 2009

TIME examines discrimination against HIV-positive children in Vietnam

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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