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Tight transmission bottlenecks may limit the evolution of SARS-CoV-2 variants

A new study describes that tight transmission bottlenecks restrict the evolution of SARS-CoV-2 in the transmission chain. SARS-CoV-2 is the causative pathogen of the COVID-19 pandemic.

18 Jan 2023

The diverse mechanisms by which galectins can regulate adaptive and innate immune responses

Researchers explored ways galectins can impact immunity and discussed the opportunities and challenges in the field.

18 Jan 2023

What does the future of clinical trials and evidence-based medicine look like?

In a recent perspective published in Nature Medicine, the researcher shared his vision and future perspectives for the domains of clinical research and evidence-based therapeutics.

18 Jan 2023

What factors are associated with successful dietary weight loss interventions?

A new study explored the factors governing the success of long- and short-term weight loss interventions.

18 Jan 2023

The efficacy of low-dose fluvoxamine compared with placebo for treating mild to moderate COVID-19 in the US

Researchers evaluated the efficacy of low-dosage fluvoxamine (50 mg two times a day) over 10 days in the management of mild and moderate-SARS-CoV-2 infections in the US.

18 Jan 2023

COVID-19 is changing behaviors related to how people are exposed to household chemicals

COVID-19 is changing household behaviors related to how we are exposed to various household chemicals linked to poor health outcomes.

18 Jan 2023

Threshold control method could aid in future non-pharmaceutical intervention relaxation policy making

Governments around the world used a variety of techniques known as nonpharmaceutical interventions, or NPIs, to control the spread of COVID-19.

18 Jan 2023

Upregulation of Robo4 expression reduces mortality from severe infection

The researchers screened a library of drugs using a mouse endothelial cell line to identify pathways that are involved in the regulation of Robo4 and found that two competitive SMAD signaling pathways appear to regulate Robo4 expression.

18 Jan 2023

What is the impact of maternal hypertension and mental disorders on neonatal outcomes?

Researchers explored the impact of maternal hypertension and mental disorders on harmful neonatal outcomes.

18 Jan 2023

Exploring a novel amplicon-based mpox virus sequencing strategy

Researchers described the development of a sequencing strategy based on amplicons for mpox detection.

18 Jan 2023

The "Great Escape" by SARS-CoV-2 XBB.1

In a recent article published in the Lancet Microbe, researchers in the Netherlands and the United Kingdom quantified the antigenic diversity of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) subvariants, BQ.1.1, BM.1.1.1, and XBB.1, all derivatives of the variant of concern (VOC) Omicron, which emerged in late 2022.

17 Jan 2023

An in-depth meta-analysis highlights COVID-19's pregnancy dangers

Researchers assess the risk of maternal, fetal, and neonatal morbidity and mortality in women diagnosed with COVID-19 during pregnancy.

17 Jan 2023

Probiotic diminishes S. aureus bacterial colonization, Phase 2 trial shows

A promising approach to control Staphylococcus aureus bacterial colonization in people-;using a probiotic instead of antibiotics-;was safe and highly effective in a Phase 2 clinical trial.

17 Jan 2023

Cancer mortality in the U.S. has declined 33% since the 90s

The American Cancer Society has recently published the statistics of cancer incidence and mortality for 2023 in CA: A Cancer Journal for Clinicians.

17 Jan 2023

Future COVID-19 control will require vaccines that induce better mucosal immunity

In a recent study posted to the medRxiv* preprint server, researchers in France explored the relationship between long-term immunoglobulin (Ig)-A response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and taste and smell disorders.

17 Jan 2023

Association between coronary artery calcium dispersion and mortality

Scientists determine whether the estimation of coronary artery calcium dispersion could determine all-cause and causes of specific mortality.

17 Jan 2023

On four flights out of China in December, 22% of passengers were SARS-CoV-2 positive

Researchers document COVID-19 screening results in Italy of 556 flight passengers from two Chinese provinces in late December 2022.

17 Jan 2023

What are the major findings of long COVID research?

Researchers explored existing literature on long coronavirus disease (COVID). They highlighted key immunological findings, similarities with other diseases, symptoms, and associated pathophysiological mechanisms, and diagnostic and therapeutic options, including COVID-19 vaccinations.

17 Jan 2023

Exploring bioinformatics approach for evaluating binding affinities of probable COVID-19 therapeutic decoys

Researchers developed a computational workflow based on molecular dynamic (MD) simulations and artificial neural network (ANN) to assess the SARS-CoV-2 spike (S) protein receptor-binding domain (RBD)-human angiotensin-converting enzyme 2 (hACE2) binding affinities of SARS-CoV-2 variants.

17 Jan 2023

Study to investigate the effects of environmental factors on antibiotic resistance

Environmental factors, including pollution, that might help 'superbugs' become resistant to antibiotics is set to be investigated by the University of Surrey.

17 Jan 2023

Disease/Infection News

Tight transmission bottlenecks may limit the evolution of SARS-CoV-2 variants

The diverse mechanisms by which galectins can regulate adaptive and innate immune responses

What does the future of clinical trials and evidence-based medicine look like?

What factors are associated with successful dietary weight loss interventions?

The efficacy of low-dose fluvoxamine compared with placebo for treating mild to moderate COVID-19 in the US

COVID-19 is changing behaviors related to how people are exposed to household chemicals

Threshold control method could aid in future non-pharmaceutical intervention relaxation policy making

Upregulation of Robo4 expression reduces mortality from severe infection

What is the impact of maternal hypertension and mental disorders on neonatal outcomes?

Exploring a novel amplicon-based mpox virus sequencing strategy

The "Great Escape" by SARS-CoV-2 XBB.1

An in-depth meta-analysis highlights COVID-19's pregnancy dangers

Probiotic diminishes S. aureus bacterial colonization, Phase 2 trial shows

Cancer mortality in the U.S. has declined 33% since the 90s

Future COVID-19 control will require vaccines that induce better mucosal immunity

Association between coronary artery calcium dispersion and mortality

On four flights out of China in December, 22% of passengers were SARS-CoV-2 positive

What are the major findings of long COVID research?

Exploring bioinformatics approach for evaluating binding affinities of probable COVID-19 therapeutic decoys

Study to investigate the effects of environmental factors on antibiotic resistance

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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