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Research may pave the way for new antibiotics to treat high bacterial density infections

Antibiotic resistant bacteria pose of the greatest threats to global public health. In 2019, deaths due to antibiotic resistant bacteria outpaced deaths due to HIV and malaria.

16 Dec 2022

Exploring COVID-19 pandemic-related increases in hospitalizations among adolescents for mental health issues

Researchers conducted a retrospective, multisite cohort study among 11 to 17-year-old adolescents in the United States of America (USA) and France.

16 Dec 2022

Genome assembly tool could spur the development of new treatments for tuberculosis

Researchers have developed a novel genome assembly tool that could spur the development of new treatments for tuberculosis and other bacterial infections.

16 Dec 2022

Excess COVID-19-associated death estimates by World Health Organization

Researchers presented a comprehensive report on the estimated impact of the SARS-CoV-2 pandemic by estimating month-wise excess deaths for the years 2020 and 2021.

16 Dec 2022

Exploring taste and smell dysfunction as strong predictors of SARS-CoV-2 infections

Researchers investigated whether coronavirus disease 2019 (COVID-19)-associated chemosensory alterations were predictive of serological responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among United States (US) residents.

16 Dec 2022

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Researchers investigated the cellular tropism, replication competence, persistence and evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in humans, and associated histopathological changes in infected tissues.

16 Dec 2022

Rapid, non-invasive detection tool could help accelerate progress in eliminating malaria

A quick, affordable, non-invasive detection tool could help accelerate progress in meeting the UN Sustainable Development Goals' target to eliminate malaria, say researchers who developed it.

16 Dec 2022

Extending the collaboration to improve research on antibiotic resistance

Research on antibiotic resistance will broaden significantly when the Center for Antibiotic Resistance Research (CARe) in Gothenburg expands.

16 Dec 2022

Trial results confirm the safety of three different Ebola vaccine regimens

Ebola epidemics occur periodically in various sub-Saharan African countries. While vaccines exist and have already received WHO Prequalification against the Zaire ebolavirus species, it is essential to pursue and intensify efforts to supplement the available data to develop a safe and effective Ebola vaccine strategies in adults and children alike.

16 Dec 2022

People of all age groups benefit more from COVID-19 vaccines than natural immunity, real-world study finds

In one of the first large, real-world studies comparing the effectiveness of COVID-19 vaccines versus natural immunity in protecting against death, hospitalizations and emergency department (ED) visits for any cause, including COVID, research-scientists from Regenstrief Institute, Indiana University School of Medicine and Vanderbilt University Medical Center report that people of all age groups benefited significantly more from vaccination than natural immunity acquired from a previous COVID infection.

16 Dec 2022

Researchers report the development of robust candidate single immunization PNP hydrogel COVID vaccines

Researchers developed a one-dose subunit vaccine for the induction of durable, potent, and broad immunity against SARS-CoV-2.

16 Dec 2022

Study finds anti-S binding antibody levels are a valid correlate of protection against Omicron BA.1/BA.2 infections

Researchers used serological measurements from a longitudinal cohort to evaluate the use of binding antibodies against the SARS-CoV-2 spike protein receptor binding domain as correlates of protection against the immune evasive Omicron subvariants BA.1 and BA.2.

16 Dec 2022

Common psychiatric medications can give some protection against COVID-19

A new meta-analysis shows that psychiatric medications can give some protection against COVID-19, with the common antidepressant fluvoxamine showing the strongest effect.

16 Dec 2022

Does nirmatrelvir and ritonavir reduce the risk of hospitalization or death among outpatients with early COVID-19?

Researchers investigated the efficacy of ritonavir and nirmatrelvir combination treatment in reducing the risk of COVID-19 severity outcomes such as hospital admissions and deaths when administered during the initial period of SARS-CoV-2 infections.

16 Dec 2022

The mpox viral load kinetics over time in various parts of the body

Researchers characterized the time to mpox virus clearance of immunocompetent individuals with mild MPX in a real-world community-based setting utilizing longitudinal information.

16 Dec 2022

Study reports that delaying surgery post-COVID-19 reduces the risk of postoperative cardiovascular issues

Researchers assessed the temporal relationship between COVID-19 diagnosis and surgery time with the risk of occurrence of cardiovascular morbidity events within 30 days of surgery.

16 Dec 2022

Study suggests most clinical studies posted to medRxiv and later published in peer-reviewed journals had concordant study characteristics, results, and interpretations

Researchers compared and determined the concordance between the study design, results, and inferences of clinical and observational studies and meta-analyses that were first posted as medRxiv preprints and were later peer-reviewed and published in journals.

16 Dec 2022

SARS-CoV-2 Omicron BQ and XBB subvariants show exceptional immune evasion properties

Researchers demonstrated the exceptional immune evasion properties of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron subvariants, BQ and XBB.

16 Dec 2022

The impact of the US vaccination program on reducing infections, hospitalizations, and deaths

A recent study reported that in the two years following the initiation of the US COVID-19 vaccination campaign, over 18 million hospitalizations and three million deaths have been prevented, and close to $1.15 trillion have been saved in medical costs.

16 Dec 2022

Data mining approaches for the detection of signals associated with pediatric post-acute sequelae of COVID-19

Researchers described tree-based scan statistics for pediatric long COVID-19.

16 Dec 2022

Disease/Infection News

Research may pave the way for new antibiotics to treat high bacterial density infections

Exploring COVID-19 pandemic-related increases in hospitalizations among adolescents for mental health issues

Genome assembly tool could spur the development of new treatments for tuberculosis

Excess COVID-19-associated death estimates by World Health Organization

Exploring taste and smell dysfunction as strong predictors of SARS-CoV-2 infections

Study shows SARS-CoV-2 infection, replication and persistence in human brain tissues

Rapid, non-invasive detection tool could help accelerate progress in eliminating malaria

Extending the collaboration to improve research on antibiotic resistance

Trial results confirm the safety of three different Ebola vaccine regimens

People of all age groups benefit more from COVID-19 vaccines than natural immunity, real-world study finds

Researchers report the development of robust candidate single immunization PNP hydrogel COVID vaccines

Study finds anti-S binding antibody levels are a valid correlate of protection against Omicron BA.1/BA.2 infections

Common psychiatric medications can give some protection against COVID-19

Does nirmatrelvir and ritonavir reduce the risk of hospitalization or death among outpatients with early COVID-19?

The mpox viral load kinetics over time in various parts of the body

Study reports that delaying surgery post-COVID-19 reduces the risk of postoperative cardiovascular issues

Study suggests most clinical studies posted to medRxiv and later published in peer-reviewed journals had concordant study characteristics, results, and interpretations

SARS-CoV-2 Omicron BQ and XBB subvariants show exceptional immune evasion properties

The impact of the US vaccination program on reducing infections, hospitalizations, and deaths

Data mining approaches for the detection of signals associated with pediatric post-acute sequelae of COVID-19

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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