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Sheep milk could be an inexpensive source of therapeutic polyclonal SARS-CoV-2 neutralizing antibodies

Researchers used sheep, a ruminant mammal, to obtain polyclonal immunoglobulins (IgGs) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Dec 2022

How is the host’s m6A mRNA profile affected during SARS-CoV-2 infection?

Researchers observed that SARS-CoV-2 infection results in loss of N6-methyladenosine modification in cellular RNAs.

15 Dec 2022

What is the role of the pediatric gut microbiome in COVID-19?

Recently, scientists have reviewed the available evidence on the gut microbiome in children with COVID-19 and published it in Microorganisms.

15 Dec 2022

Influenza vaccine effectiveness during the 2021–2022 influenza season in the United States

Researchers estimated influenza VE in patients aged ≥6 months seeking outpatient care for ARI due to the influenza A(H3N2) virus between October 2021 and April 2022 in the United States (US).

15 Dec 2022

Randomized trials demonstrate the safety of Ebola vaccine regimens in adults and children

Two randomized, placebo-controlled trials evaluating three Ebola vaccine administration strategies in adults and children found that all the regimens were safe in both age groups, according to results published today in the New England Journal of Medicine.

15 Dec 2022

Study assesses COVID-19 booster vaccination coverage by demographics and behaviors and experiences toward vaccination among fully vaccinated adults

An early release from the CDC, USA, examines the coverage of booster doses among adults in the USA.

15 Dec 2022

‘Cocktail’ vaccines could offer protection against current and future SARS-CoV-2 'variants of concern'

COVID-19 vaccinations that combine two or more distinct variants of the SARS-CoV-2 virus could offer protection against both current and future 'variants of concern', say scientists at the University of Cambridge and Medical University of Innsbruck.

15 Dec 2022

Similarities and differences in secondary health effects after disasters and pandemics

Disasters and pandemics can affect the physical and psychological health of the people involved even after the events have occurred.

15 Dec 2022

Research reveals that a viral toxin may contribute to the severity of COVID-19

Researchers determine whether the SARS-CoV-2 spike protein influences endothelial and epithelial barrier dysfunction and vascular leakage.

14 Dec 2022

Correlating circulating adipokine levels with COVID-19 severity

Researchers determine whether plasma adipokine levels were associated with COVID-19-related systemic inflammation and severity.

14 Dec 2022

No benefit of low dose apixaban following acute COVID-19

The HEAL-COVID trial compared the efficacy of Apixaban to standard care in adults who have recently recovered from severe COVID-19.

14 Dec 2022

The debilitating effects of long-COVID in the U.S.

A new study posted to the preprint server medRxiv* discusses chronic disability due to long COVID in the United States.

14 Dec 2022

Avian influenza update: Bird keepers in England must house all poultry and captive birds until further notice

All poultry and captive birds must be housed in England until further notice, following an increase in the number of detections of avian influenza in wild birds and on commercial premises.

14 Dec 2022

People with cocaine- and opioid-use disorders infected with COVID-19 have greater risk of endocarditis

People diagnosed with cocaine- and opioid-use disorders are more susceptible to developing endocarditis, a condition that damages the lining of the heart valves and chambers, according to research from the Case Western Reserve University School of Medicine and National Institute on Drug Abuse, part of the National Institutes of Health.

14 Dec 2022

Bioinformatics approach for the design of siRNAs against SARS-CoV-2

Scientists have developed a set of siRNAs against SARS-CoV-2 using computational approaches.

14 Dec 2022

The implications of pulmonary tissue-resident memory T lymphocytes in COVID-19 and other respiratory diseases

Researchers elucidated the mechanisms of long-term T lymphocyte lodgement in tissues other than lymphoid tissues and the reasons for the transient residency of specific subsets of tissue-resident memory T (TRM) lymphocytes.

14 Dec 2022

What are the risk factors associated with symptomatic SARS-CoV-2 and rhinovirus infection in King County, Washington, from June 2020 to July 2022?

Researchers evaluated the change in symptoms and risk factors associated with positive SARS-CoV-2 tests during the COVID-19 pandemic and compared it to those associated with positive tests of other respiratory viruses among residents of King County, Washington, in the United States.

14 Dec 2022

The evolution of COVID-19 mortality during 2020 and 2021 in six countries

Researchers analyzed the mortality in selected countries during multiple waves of the COVID-19 pandemic in 2020 and 2021 to understand the evolution of COVID-19-related mortality according to age and sex.

14 Dec 2022

Polymorphisms in human immunoglobulin heavy chain genes can influence the function of SARS-CoV-2 neutralizing antibodies

Researchers isolated SARS-CoV-2 spike protein-targeted mAbs from convalescent healthcare workers, emphasizing the IGHV1-69 gene, the gene with the greatest structural and allelic variation.

14 Dec 2022

Study indicates need for developing mucosal vaccines to induce potent immune responses at sites where SARS-CoV-2 infection occurs

Researchers measured the antibodies against SARS-CoV-2 from nasal fluid, saliva, and plasma to compare the antibody levels between blood and mucosal fluids.

14 Dec 2022

Disease/Infection News

Sheep milk could be an inexpensive source of therapeutic polyclonal SARS-CoV-2 neutralizing antibodies

How is the host’s m6A mRNA profile affected during SARS-CoV-2 infection?

What is the role of the pediatric gut microbiome in COVID-19?

Influenza vaccine effectiveness during the 2021–2022 influenza season in the United States

Randomized trials demonstrate the safety of Ebola vaccine regimens in adults and children

Study assesses COVID-19 booster vaccination coverage by demographics and behaviors and experiences toward vaccination among fully vaccinated adults

‘Cocktail’ vaccines could offer protection against current and future SARS-CoV-2 'variants of concern'

Similarities and differences in secondary health effects after disasters and pandemics

Research reveals that a viral toxin may contribute to the severity of COVID-19

Correlating circulating adipokine levels with COVID-19 severity

No benefit of low dose apixaban following acute COVID-19

The debilitating effects of long-COVID in the U.S.

Avian influenza update: Bird keepers in England must house all poultry and captive birds until further notice

People with cocaine- and opioid-use disorders infected with COVID-19 have greater risk of endocarditis

Bioinformatics approach for the design of siRNAs against SARS-CoV-2

The implications of pulmonary tissue-resident memory T lymphocytes in COVID-19 and other respiratory diseases

What are the risk factors associated with symptomatic SARS-CoV-2 and rhinovirus infection in King County, Washington, from June 2020 to July 2022?

The evolution of COVID-19 mortality during 2020 and 2021 in six countries

Polymorphisms in human immunoglobulin heavy chain genes can influence the function of SARS-CoV-2 neutralizing antibodies

Study indicates need for developing mucosal vaccines to induce potent immune responses at sites where SARS-CoV-2 infection occurs

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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