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Human T cell immunity is coping with mutations in SARS-CoV-2 variants of concern

Immune T cells are continuing to target the spike protein of SARS-CoV-2 variants of concern, although mutations are making some T cells less effective, according to new research.

1 Dec 2022

Prior infection and vaccination protects against severe outcomes from SARS-CoV-2 Omicron infection

Previous infection with SARS-CoV-2 and booster vaccination protect against ICU admission and mortality following infection with the Omicron variant.

1 Dec 2022

COVID-19 infection may lead to long-term liver injury

COVID-19 infection is associated with increased liver stiffness, a sign of possible long-term liver injury, according to the results of a new study being presented today at the annual meeting of the Radiological Society of North America.

1 Dec 2022

Two experimental mRNA vaccines highly effective in reducing malaria infection and transmission

Malaria is found in more than 90 countries around the world, causing 241 million cases and an estimated 627,000 deaths every year.

1 Dec 2022

Risk factor assessment for the development of severe SARS-CoV-2 breakthrough infections

researchers evaluated the severity of breakthrough SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infections and the risk factors associated with severity among individuals vaccinated for coronavirus disease 2019 (COVID-19) in Sousse, Tunisia.

1 Dec 2022

Are medical masks non-inferior to N95 respirators to prevent COVID-19 in health care workers providing routine care?

Researchers determined whether medical masks were non-inferior to N95 respirators in preventing a SARS-CoV-2)infection in healthcare workers.

1 Dec 2022

Novel prefusion S antigen designed by the mutation of the SARS-CoV-2 Spike protein’s trimeric structure

Researchers mutated the SARS-CoV-2 spike protein's trimeric structure to design a novel prefusion S antigen, S2D14.

1 Dec 2022

Researchers explore failed SARS-CoV-2 screening at hospital entrances

Researchers evaluated the failure rates of COVID-19 screening at hospital entrances for visitors, health professionals, and patients at the Yale New Haven Hospital in the US.

1 Dec 2022

The requirement for Fc effector functions to protect against SARS-CoV-2 infection

Researchers determined which specific fragment crystallizable effector functions protect against SARS-CoV-2 infection, especially its emerging variants.

1 Dec 2022

Impact of COVID-19 on sperm quality

Researchers examined the effect of coronavirus disease 2019 (COVID-19) on sperm quality.

1 Dec 2022

The incidence of antimicrobial resistance among urinary E. coli isolates is increasing in both hospital and community settings in Australia

Researchers comparatively evaluated trends in AMR among urinary Escherichia coli strains from a private, commercial community-based laboratory and a public HB laboratory in the Illawarra Shoalhaven area located in NSW, Australia.

1 Dec 2022

Detection of filoviruses by the innate immune system

In a new study, researchers examined how the innate immune system detects filoviruses.

1 Dec 2022

Study reveals major problems and gaps in Canada's process of mandatory HIV screening of migrants

A new landmark study finds that Canada's process of mandatory HIV screening of migrants is out of step with the OECD and ignores the government's own policy on medical admissibility to Canada.

30 Nov 2022

SARS-CoV-2 can cause hyperglycemia in cats

In a recent study published in The Journal of Infectious Diseases, researchers explored the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and hyperglycemia in cats.

30 Nov 2022

Detection of early-formed, antigen-specific clones in SARS-CoV-2-reactive B cells after longitudinal analysis

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causal agent of the coronavirus disease 2019 (COVID-19) pandemic, has globally infected more than 639 million individuals and claimed over 6.6 million lives. Despite the rapid commencement of COVID-19 vaccination programs in most countries across the world, the virus has remained in circulation.

30 Nov 2022

Severe undernutrition increases risk of unfavorable outcomes for individuals undergoing TB treatment

In 2021, an estimated 10.6 million individuals developed tuberculosis (TB) and 1.6 million died, making it the second most lethal infection in the world after SARS-CoV-2.

30 Nov 2022

More than half of U.S. adults weren’t concerned about the flu season, survey shows

As flu-related hospitalizations soar to record early season levels, the American Heart Association, a global force for longer, healthier lives for all, is concerned many people will be caught off-guard by this health threat and urges prompt vaccination against the virus.

30 Nov 2022

Study shows SARS-CoV-2 VOCs disseminated around the world according to different spatial source-sink dynamics

Researchers assessed the dispersion patterns of SARS-CoV-2 variants and their global expansion.

30 Nov 2022

Phase 2/3 clinical trial shows that Clover’s vaccine candidate reduces household transmission of SARS-CoV-2

Clover Biopharmaceuticals, Ltd., a global clinical-stage biotechnology company developing novel vaccines and biologic therapeutics, and the International Vaccine Institute, an international nonprofit organization devoted to providing vaccines critical to global public health and based in Seoul, Korea, today announced that Clinical Infectious Diseases has published additional data from SPECTRA, a global Phase 2/3 clinical trial, that showed vaccination with SCB-2019 (CpG 1018/Alum) reduced the risk of transmitting SARS-CoV-2 infection to household members, compared to placebo participants.

30 Nov 2022

Researchers receive $3 million-plus NIH grant to develop treatment for drug-resistant fungus

With a new $3 million-plus grant from the National Institutes of Health (NIH), Case Western Reserve University researchers are examining the next level of treatment for Candida auris (C.auris), a multidrug-resistant yeast that causes serious infection and, in some cases, death.

30 Nov 2022

Disease/Infection News

Human T cell immunity is coping with mutations in SARS-CoV-2 variants of concern

Prior infection and vaccination protects against severe outcomes from SARS-CoV-2 Omicron infection

COVID-19 infection may lead to long-term liver injury

Two experimental mRNA vaccines highly effective in reducing malaria infection and transmission

Risk factor assessment for the development of severe SARS-CoV-2 breakthrough infections

Are medical masks non-inferior to N95 respirators to prevent COVID-19 in health care workers providing routine care?

Novel prefusion S antigen designed by the mutation of the SARS-CoV-2 Spike protein’s trimeric structure

Researchers explore failed SARS-CoV-2 screening at hospital entrances

The requirement for Fc effector functions to protect against SARS-CoV-2 infection

Impact of COVID-19 on sperm quality

The incidence of antimicrobial resistance among urinary E. coli isolates is increasing in both hospital and community settings in Australia

Detection of filoviruses by the innate immune system

Study reveals major problems and gaps in Canada's process of mandatory HIV screening of migrants

SARS-CoV-2 can cause hyperglycemia in cats

Detection of early-formed, antigen-specific clones in SARS-CoV-2-reactive B cells after longitudinal analysis

Severe undernutrition increases risk of unfavorable outcomes for individuals undergoing TB treatment

More than half of U.S. adults weren’t concerned about the flu season, survey shows

Study shows SARS-CoV-2 VOCs disseminated around the world according to different spatial source-sink dynamics

Phase 2/3 clinical trial shows that Clover’s vaccine candidate reduces household transmission of SARS-CoV-2

Researchers receive $3 million-plus NIH grant to develop treatment for drug-resistant fungus

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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