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Isolated monoclonal antibodies targeting SARS-CoV-2 S1/S2 cleavage effective against Delta and Omicron

Isolated monoclonal antibodies neutralize SARS-CoV-2 Delta and Omicron variants.

28 Nov 2022

Innovative trial aims to quickly find effective flu treatments

A new national trial, launched today, aims to use pandemic lessons to help quickly find effective treatments for people hospitalized with severe flu.

28 Nov 2022

Machine learning pinpoints the most accurate timelines for predicting Alzheimer's progression

A Cornell-led collaboration used machine learning to pinpoint the most accurate means, and timelines, for anticipating the advancement of Alzheimer's disease in people who are either cognitively normal or experiencing mild cognitive impairment.

28 Nov 2022

Meta-analysis informs a change to treatment guidelines for uncomplicated malaria in the first trimester of pregnancy

A new WWARN meta-analysis commissioned by the World Health Organization (WHO) which informed a change to its treatment guidelines has been published in The Lancet.

28 Nov 2022

Acute COVID-19 infection disrupts a healthy balance between good and bad gut microbes

In an intensive look at the effects of the virus causing COVID-19 on patients' microbiome – the collection of microorganisms that live in and on the human body – Rutgers scientists found that acute infection disrupts a healthy balance between good and bad microbes in the gut, especially with antibiotic treatment.

28 Nov 2022

Scientists unravel how bats harbor many viruses without developing symptoms

Bats are asymptomatic carriers of a multitude of viruses that are pathogenic to most other mammals. How has their immune system evolved to shield them from these pathogens?

28 Nov 2022

Study on the immunogenicity of monkeypox virus messenger ribonucleic acid-based vaccine candidates

In a new study, researchers developed two monkeypox (MPX) virus (MPXV) quadrivalent messenger ribonucleic acid (mRNA) vaccines, mRNA-A-lipid nanoparticle (LNP) and mRNA-B-LNP.

28 Nov 2022

Establishment of quantitative scale for long COVID stigma estimation among UK residents

Researchers developed and validated the long coronavirus disease (COVID) stigma scale (LCSS) to quantify the burden of long COVID stigma in the United Kingdom (UK).

28 Nov 2022

Oral anticoagulant does not help patients recovering from moderate and severe COVID-19

A drug used to reduce the risk of blood clots does not help patients recovering from moderate and severe COVID-19, despite this approach being offered to patients, a UK-wide trial, led by Addenbrooke's Hospital and the University of Cambridge has found.

28 Nov 2022

Molecular and cellular similarities identified in the brains of SARS-CoV-2 and Alzheimer's disease patients

Researchers evaluated neuro-pathophysiological consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, especially the post-acute sequelae of SARS-CoV-2 (PASC) in Alzheimer’s disease (AD) patients.

28 Nov 2022

Characterization of bat viromes reveals the co-infection, spillover, and emergence risk of several zoonotic viruses

Researchers characterized the mammal-infecting viruses in 149 bats, representing six genera and 15 species, sampled from Yunnan province, China using an unbiased meta-transcriptomics approach.

28 Nov 2022

New research helps to better understand the risks associated with prenatal Zika virus infections

Approximately one third of children born to mothers infected with Zika virus during their pregnancy present with at least one abnormality consistent with Congenital Zika Syndrome in the first years of their life, according to new research.

28 Nov 2022

The frequency, magnitude, and longevity of natural antibody responses against nine P. vivax vaccine candidate proteins

A new study aimed to evaluate the magnitude, longevity, and prevalence of naturally acquired IgG antibody responses against 9 P. vivax vaccine candidate antigens in patients with acute vivax malaria and were followed up for 180 days.

28 Nov 2022

Cryo-electron tomography helps visualize platelet deformation due to SARS-CoV-2 spike protein

Researchers used cellular cryo-electron tomography (cryo-ET) to demonstrate the role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein in coronavirus disease 2019 (COVID-19)-triggered severe coagulopathies.

28 Nov 2022

Possibility of the first fluid biomarker that reflects brain pathology in primary tauopathies

Addressing this gap in research, a recent Nature Medicine study hypothesized that 4R isoform-specific MTBR-tau species accumulate in the patient’s brain of specific subtypes of 4R tauopathies.

28 Nov 2022

Feline coronavirus-infected domesticated cats found to possess cross-reactive anti-SARS-CoV-2 antibodies

In a recent study, researchers confirmed that feline coronavirus infection induced the production of cross-reactive antibodies against the SARS-CoV-2 receptor-binding domain in domestic cats.

28 Nov 2022

The potential for automatic diagnosis of palpable breast lumps without a radiologist or sonographer

A new study evaluated the efficacy of the volume sweep imaging ultrasound scans and artificial intelligence in providing fully automated and inexpensive breast ultrasound scans and interpretation without the need for experienced radiologists or sonographers.

28 Nov 2022

Disease/Infection News

Isolated monoclonal antibodies targeting SARS-CoV-2 S1/S2 cleavage effective against Delta and Omicron

Innovative trial aims to quickly find effective flu treatments

Machine learning pinpoints the most accurate timelines for predicting Alzheimer's progression

Meta-analysis informs a change to treatment guidelines for uncomplicated malaria in the first trimester of pregnancy

Acute COVID-19 infection disrupts a healthy balance between good and bad gut microbes

Scientists unravel how bats harbor many viruses without developing symptoms

Study on the immunogenicity of monkeypox virus messenger ribonucleic acid-based vaccine candidates

Establishment of quantitative scale for long COVID stigma estimation among UK residents

Oral anticoagulant does not help patients recovering from moderate and severe COVID-19

Molecular and cellular similarities identified in the brains of SARS-CoV-2 and Alzheimer's disease patients

Characterization of bat viromes reveals the co-infection, spillover, and emergence risk of several zoonotic viruses

New research helps to better understand the risks associated with prenatal Zika virus infections

The frequency, magnitude, and longevity of natural antibody responses against nine P. vivax vaccine candidate proteins

Cryo-electron tomography helps visualize platelet deformation due to SARS-CoV-2 spike protein

Possibility of the first fluid biomarker that reflects brain pathology in primary tauopathies

Feline coronavirus-infected domesticated cats found to possess cross-reactive anti-SARS-CoV-2 antibodies

The potential for automatic diagnosis of palpable breast lumps without a radiologist or sonographer

Researchers use a comparative study to model RSV prevention in children

Glycan signatures in rheumatic diseases and their associated functional implications

Modeling study offers a road map for public health to maximize the impact of monkeypox vaccines

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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