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Evolution of the SARS-CoV-2 omicron variant

Study shows that the omicron variant shares a common ancestry with the VOI lambda and has evolved mainly because of non-synonymous mutations.

9 Dec 2021

Challenges of bereavement during the COVID-19 pandemic

A new study aims to generate an understanding of the overall challenges that the people experiencing bereavement during the COVID-19 pandemic face.

9 Dec 2021

Novel waveform-based approach to determine the propensity of betacoronaviruses to infect humans

Scientists attempt to understand the evolution of the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2.

9 Dec 2021

Study of individuals referred to a cardiovascular disease clinic designed for patients with long COVID

Scientists discuss the characteristics, diagnostic evaluations, and cardiac diagnoses in patients referred to a clinic designed for patients with PASC.

9 Dec 2021

Disparities in COVID-19 burden among high-risk communities

New study findings demonstrate that non-Whites, lower-income individuals, and individuals with lower education levels have the highest SARS-CoV-2 seroprevalence and lowest vaccination seroprevalence.

9 Dec 2021

Kinetics and persistence of SARS-CoV-2 antibody responses

New study findings indicate that antibody detection shows a distinct pattern depending on the type of antibody detected, the target antigen, the test design, antibody avidity level, and COVID-19 severity.

9 Dec 2021

Effect of SARS-CoV-2 variant emergence on efficacy of neutralizing antibodies and vaccines

A review article focuses on the efficacy of neutralizing antibodies and vaccines against the SARS-CoV-2 variants.

9 Dec 2021

Immune responses against SARS-CoV-2 Delta variant after BNT162b2 vaccination in people living with HIV

Researchers from Sorbonne Universite have been investigating the effect of the BNT162b2 mRNA vaccine on HIV-positive individuals.

9 Dec 2021

Increased risk of COVID-19 breakthrough infections in fully vaccinated people with HIV

New study results showed a 41% greater incidence of breakthrough infections in people with HIV compared to that of people without HIV.

9 Dec 2021

Glycans strengthen and lengthen SARS-Cov-2 spike binding to ACE2

New study results provide evidence that the binding between SARS-CoV-2 RBD and host ACE2 receptor is aided by the glycosylation on each protein.

9 Dec 2021

Youths did not seek healthcare both before and during the COVID-19 pandemic

New study results show that although healthcare access patterns among youth were similar before and during the pandemic, COVID-19 has added some new barriers to seeking medical care when needed.

9 Dec 2021

Potential association between senescence and aging in COVID-19

A review published in Cells discussed characteristics of cellular senescence and its potential role in COVID-19.

9 Dec 2021

Immunogenicity and safety of COVID-19 subunit vaccine Nanocovax in animal models

Researchers have developed Nanocovax, a COVID-19 subunit vaccine based on recombinant protein technology to produce the extracellular (soluble) portion of the S protein of SARS-CoV-2.

9 Dec 2021

Positive results from Phase 3 study of Medicago’s plant-based COVID-19 vaccine candidate announced

Medicago, a biopharmaceutical company headquartered in Quebec City, and GlaxoSmithKline today announce positive efficacy and safety results from the global Phase 3 placebo-controlled efficacy study of Medicago’s plant-based COVID-19 vaccine candidate in combination with GSK’s pandemic adjuvant, conducted in over 24,000 subjects, adults 18 years and above, across six countries.

9 Dec 2021

Sugar-binding pockets in N-terminal domain may increase SARS-CoV-2 infectivity

The N-terminal domain has a fold that can bind sugar, and new research led by Jonathan Lees from Oxford Brookes University found the sugar-binding pockets near the N-terminal domain help to increase viral infectivity. Furthermore, the findings show that the SARS-CoV-2 sugar-binding pockets are evolving with added loops observed in the pockets of new variants.

9 Dec 2021

Mass-spectrometry and PCR testing identifies various targets related to SARS-CoV-2 VOCs

New research posted to the medRxiv* preprint server suggests that the Agena MassARRAY SARS-CoV-2 Panel PCR test effectively detects a variety of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants.

9 Dec 2021

SARS-CoV-2 variants are evolving new ways to evade antibodies and vaccines

Continued replication of severe acute respiratory syndrome-associated coronavirus 2 (SARS-CoV-2) under selective pressure from natural and vaccine-induced immunity has led to the emergence of variants of concern (VOCs) with increased transmissibility or virulence.

8 Dec 2021

For most young people, COVID vaccine-related myocarditis is not serious

A new study published in the journal Circulation aimed to describe a large case series of suspected myocarditis temporally related with the COVID-19 vaccine in adolescents and young adults below 21 years of age across the United States and Canada.

8 Dec 2021

Neutralization antibodies elevated in nursing home residents after COVID-19 mRNA boosters

Researchers from the United States, in their recent study published on the preprint server medRxiv*, have evaluated the humoral responses to third vaccine dose in nursing home residents and healthcare workers (HCW) and found that that second booster (or third vaccine dose) significantly increased anti-spike, anti-receptor binding domain (RBD), and neutralization titers in almost all nursing home residents and HCW to considerably higher levels than what was attained after the completion of the initial two-dose vaccine series.

8 Dec 2021

Omicron binds to ACE2 with high affinity, enhancing its transmissibility and infectivity

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8 Dec 2021

Disease/Infection News

Evolution of the SARS-CoV-2 omicron variant

Challenges of bereavement during the COVID-19 pandemic

Novel waveform-based approach to determine the propensity of betacoronaviruses to infect humans

Study of individuals referred to a cardiovascular disease clinic designed for patients with long COVID

Disparities in COVID-19 burden among high-risk communities

Kinetics and persistence of SARS-CoV-2 antibody responses

Effect of SARS-CoV-2 variant emergence on efficacy of neutralizing antibodies and vaccines

Immune responses against SARS-CoV-2 Delta variant after BNT162b2 vaccination in people living with HIV

Increased risk of COVID-19 breakthrough infections in fully vaccinated people with HIV

Glycans strengthen and lengthen SARS-Cov-2 spike binding to ACE2

Youths did not seek healthcare both before and during the COVID-19 pandemic

Potential association between senescence and aging in COVID-19

Immunogenicity and safety of COVID-19 subunit vaccine Nanocovax in animal models

Positive results from Phase 3 study of Medicago’s plant-based COVID-19 vaccine candidate announced

Sugar-binding pockets in N-terminal domain may increase SARS-CoV-2 infectivity

Mass-spectrometry and PCR testing identifies various targets related to SARS-CoV-2 VOCs

SARS-CoV-2 variants are evolving new ways to evade antibodies and vaccines

For most young people, COVID vaccine-related myocarditis is not serious

Neutralization antibodies elevated in nursing home residents after COVID-19 mRNA boosters

Omicron binds to ACE2 with high affinity, enhancing its transmissibility and infectivity

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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