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SARS-CoV-2 Delta variant associated with more breakthrough infections

The study highlights that compared to the previously circulating alpha variant, the delta variant is associated with higher infectious virus load and a lower level of humoral immunity in the upper respiratory tract. The study is currently available on the medRxiv* preprint server prior to peer review.

24 Aug 2021

UCR researchers gauge social responsibility in reducing COVID-19 spread

Uncertainty and anxiety generated by the COVID-19 pandemic motivated social psychologist Evelyn Vázquez at the University of California, Riverside, to collaborate with UCR Healthy Campus on a study to identify safety measures and public health messaging that reduce the spread of the coronavirus within campus communities.

24 Aug 2021

Frameshift deletion mutation in ORF7a may provide fitness advantage to Australia's SARS-CoV-2 delta variants

A team of scientists from Australia has recently identified a frameshift deletion mutation in ORF7a of the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The mutation results in the production of a truncated peptide with altered functionality. The study is currently available on the medRxiv* preprint server while awaiting peer review.

24 Aug 2021

Patients on dialysis show reduced antibody levels four months after COVID-19 vaccination

A new longitudinal study posted to the medRxiv* preprint server suggests vaccinated patients on chronic hemodialysis having waning immunity against severe acute respiratory syndrome 2 (SARS-CoV-2) variants of concern. The German researchers found a drop in neutralizing antibody levels and T cell activity four months after receiving their second Pfizer-BioNTech vaccine.

24 Aug 2021

Extreme novel pandemics more likely to occur in the future, statistical study reveals

The COVID-19 pandemic may be the deadliest viral outbreak the world has seen in more than a century. But statistically, such extreme events aren't as rare as we may think, asserts a new analysis of novel disease outbreaks over the past 400 years.

24 Aug 2021

Synthetic SARS-CoV-2 vs. SARS-CoV-2

Though vaccination efforts are underway in most countries, there are still limited options for treating COVID-19. Now, researchers at Penn State designed a new COVID-19 therapy that uses a defective synthetic version of the SARS-CoV-2 virus to interfere with the actual virus's replication.

23 Aug 2021

Study pinpoints an enzyme with a significant impact on SARS-CoV-2 replication

By applying a systems biology approach, a recent bioRxiv* preprint research paper by scientists from the Icahn School of Medicine at Mount Sinai in New York unveils interactions between the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) and p38 mitogen-activated protein kinase (MAPK) pathway responsible for regulating the expression of crucial inflammatory mediators in human lung epithelial cells.

23 Aug 2021

Study suggests algorithm may help optimize future COVID-19 vaccine design

Scientists predict the COVID-19 pandemic is on its way to becoming endemic. The rising spread of COVID-19 variants such as Delta has helped infect unvaccinated and some vaccinated individuals. COVID-19 vaccines continue to be the best way to protect against severe illness and death, but there may be a need for vaccines to protect against a specific variant.

23 Aug 2021

COVID booster shots might be needed in subgroup of HIV-positive individuals

The coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved into a global pandemic destroying lives and economies. COVID-19 is not curable, so vaccines are the only safeguard during this pandemic.

23 Aug 2021

Study: Awake prone positioning can reduce the need for mechanical ventilation in COVID-19 patients

A six country clinical study of more than 1,100 hospitalized COVID-19 patients who required high-flow nasal cannula oxygen therapy suggests that prone positioning (rotating patients with severe breathing issues so they are face down) soon after admission can significantly reduce the need for mechanical ventilation.

23 Aug 2021

Lipid-lowering drug TriCor dramatically cuts treatment time for severe COVID-19 patients

The SARS-CoV-2 virus has infected over 165 million people worldwide causing nearly 3.5 million deaths. Recent vaccination efforts have been hindered by multiple coronavirus variants that challenge current vaccines.

23 Aug 2021

SARS-CoV-2 alpha variant exhibits enhanced household transmission

In a recent study, the transmission rate of wildtype and the Alpha variant of SARS-CoV-2 through households is tracked.

23 Aug 2021

Broad-spectrum coronavirus neutralization amongst vaccinated SARS-CoV-1 survivors

The potency of neutralizing antibodies in individuals who have recovered from SARS-CoV and received the SARS-CoV-2 vaccine is evaluated.

23 Aug 2021

CUNY SPH and NYC Health Department receive grant to study long-acting injectables for HIV

The National Institute of Mental Health has awarded the CUNY Graduate School of Public Health and Health Policy and the New York City Department of Health and Mental Hygiene a thirty month grant to support long-acting injectable antiretroviral therapy access, uptake, and adherence among people with HIV enrolled in the Ryan White HIV/AIDS Program (hereafter "Ryan White").

23 Aug 2021

VALIDATE Network’s TB vaccine work receives $1.5 million funding boost

The Oxford-run VALIDATE Network has received $1.5 million in funding for its tuberculosis vaccine work from the Bill & Melinda Gates Foundation.

23 Aug 2021

Electronic health systems helped increase HBV screenings during COVID-19 pandemic

At the beginning of the COVID-19 pandemic, community health clinics saw a significant drop in patient visits. Important screenings like those for the hepatitis B virus (HBV) were getting missed, which was a setback for a local program called END B to end the transmission of HBV-;a leading risk factor for liver cancer.

23 Aug 2021

FDA approves COVID-19 mRNA vaccine that uses fundamental Penn technology

The U.S. Food and Drug Administration has given the first full approval to a COVID-19 mRNA vaccine, which uses modified mRNA technology invented and developed by scientists in the Perelman School of Medicine at the University of Pennsylvania, whose years of research in mRNA science laid a critical piece of the foundation for the largest global vaccination campaign in history.

23 Aug 2021

Expansion of seasonal betacoronavirus antibodies post-vaccination is associated with reduction in neutralization of the SARS-CoV-2 variants of concern

A new study determined the antibody response to SARS-CoV-2 and seasonal viruses induced by BNT162b2-Comirnaty vaccination in healthcare workers.

23 Aug 2021

How have SARS-CoV-2 variants of concern impacted national case fatality rates?

A new study aims to analyze the degree to which the new VoCs cause fluctuations in daily case fatality rates (CFR) across several countries.

23 Aug 2021

Does SARS-CoV-2 affect male fertility?

A recently published review describes the state of current knowledge regarding the impact of SARS-CoV-2 on the male reproductive system.

23 Aug 2021

Disease/Infection News

SARS-CoV-2 Delta variant associated with more breakthrough infections

UCR researchers gauge social responsibility in reducing COVID-19 spread

Frameshift deletion mutation in ORF7a may provide fitness advantage to Australia's SARS-CoV-2 delta variants

Patients on dialysis show reduced antibody levels four months after COVID-19 vaccination

Extreme novel pandemics more likely to occur in the future, statistical study reveals

Synthetic SARS-CoV-2 vs. SARS-CoV-2

Study pinpoints an enzyme with a significant impact on SARS-CoV-2 replication

Study suggests algorithm may help optimize future COVID-19 vaccine design

COVID booster shots might be needed in subgroup of HIV-positive individuals

Study: Awake prone positioning can reduce the need for mechanical ventilation in COVID-19 patients

Lipid-lowering drug TriCor dramatically cuts treatment time for severe COVID-19 patients

SARS-CoV-2 alpha variant exhibits enhanced household transmission

Broad-spectrum coronavirus neutralization amongst vaccinated SARS-CoV-1 survivors

CUNY SPH and NYC Health Department receive grant to study long-acting injectables for HIV

VALIDATE Network’s TB vaccine work receives $1.5 million funding boost

Electronic health systems helped increase HBV screenings during COVID-19 pandemic

FDA approves COVID-19 mRNA vaccine that uses fundamental Penn technology

Expansion of seasonal betacoronavirus antibodies post-vaccination is associated with reduction in neutralization of the SARS-CoV-2 variants of concern

How have SARS-CoV-2 variants of concern impacted national case fatality rates?

Does SARS-CoV-2 affect male fertility?

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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