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Study explores link between threat sensitivity and social conservatism

Researchers studying the intersection of politics and psychology have long documented a link between threat sensitivity and social conservatism: People who are more socially conservative tend to react more strongly to threats. Conversely, those who are more socially liberal tend to be less sensitive to threats, viewing the world as a generally safe place and embracing change to explore new possibilities.

1 Jul 2021

New article focuses on drug discovery targeting SARS-CoV-2

The July edition of SLAS Discovery is a Special Edition featuring the cover article, "Development of a High-Throughput Screening Assay to Identify Inhibitors of the SARS-CoV-2 Guanine-N7-Methyltransferase Using RapidFire Mass Spectrometry" by Lesley-Anne Pearson, Charlotte J. Green, Ph.D., De Lin, Ph.D., Alain-Pierre Petit, Ph.D., David W. Gray, Ph.D., Victoria H. Cowling, Ph.D., and Euan A. F. Fordyce, Ph.D., (Drug Discovery Unit, School of Life Sciences, University of Dundee, Dundee, UK).

1 Jul 2021

Scientists reveal the role of newly introduced lineages in COVID-19 resurgence in Europe

Following the first wave of SARS-CoV-2 infections in spring 2020, Europe experienced a resurgence of the virus starting late summer. Although it appears clear that travel had a significant impact on the circulation of the virus, it remains challenging to assess how it may have restructured and reignited the epidemic in the different European countries.

1 Jul 2021

Ion channel conserved in coronaviruses a potential new drug target for COVID therapeutics

To this end, a recent study published in Nature Structural & Molecular Biology discusses the structures of the SARS-CoV-2 ORF3a using cryo-electron microscopy (cryo-EM).

30 Jun 2021

Study highlights changes within SARS-CoV-2 variants that could be exploited to design effective inhibitors

A computational study that analyzes and explores the time-based structures of the SARS-CoV-2 variants with specific spike (S) protein mutations is discussed here.

30 Jun 2021

First demonstration of COVID-19-like response by an essential virus encoded protein by SARS-CoV-2 in vivo

Researchers from collaborating universities in Virginia have recently utilized transgenic mice to explore the effects of SARS-CoV-2 on associated lung injury.

30 Jun 2021

Alpha variant mutations help SARS-CoV-2 overcome evolutionary weaknesses

The study, published in the journal Cell Reports, showed that the mutations in the virus, particularly the deletion of two amino acids H69/V70 seen in the Alpha variant (B.1.1.7), enables the virus to overcome weaknesses as it evolves.

30 Jun 2021

Behavior modification key to prevent COVID-19, study shows

One of the longest-running studies examining COVID-prevention behaviors shows hygiene changes have been sustained but not complex changes, like social distancing, with important policy implications.

30 Jun 2021

Novel candidate malaria vaccine confers high levels of durable protection

Two U.S. Phase 1 clinical trials of a novel candidate malaria vaccine have found that the regimen conferred unprecedentedly high levels of durable protection when volunteers were later exposed to disease-causing malaria parasites.

30 Jun 2021

Frequent testing increases chance of detecting COVID-19 infections

The chance of detecting the virus that causes COVID-19 increases with more frequent testing, no matter the type of test, a new study found. Both polymerase chain reaction and antigen tests, paired with rapid results reporting, can achieve 98% sensitivity if deployed at least every three days.

30 Jun 2021

Antibody development against SARS-CoV-2 following Moderna vaccine

In a paper recently uploaded to the preprint server medRxiv* by Belda et al. (June 27th, 2021) two seroconversion panels containing the sera of individuals that received the Moderna (mRNA-1273) vaccine are compared, and the impact on neutralizing IgG antibody titers in these individuals is analyzed.

30 Jun 2021

Moderna's COVID vaccine effective against emerging variants including Delta

Researchers in the United States have analyzed the neutralizing activity of Moderna’s mRNA-1273 vaccine against several variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

30 Jun 2021

Study provides important insights into early stages of SARS-CoV-2 infection

Researchers in the UK have provided important new insights into the early stages of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

30 Jun 2021

Sanaria researchers make progress in the development of highly protective malaria vaccine

Researchers from Sanaria Inc. and the National Institutes of Health are making progress in the development of highly protective malaria vaccines.

30 Jun 2021

UC screening program helps detect HIV outbreaks among persons who inject drugs

Newly published research shows that a screening program in the University of Cincinnati Medical Center Emergency Department helped detect an outbreak of HIV among persons who inject drugs in Hamilton County, Ohio, from 2014-18.

30 Jun 2021

Solar irradiation inactivates SARS-CoV-2 and other human coronaviruses, finds study

Coronaviruses irradiated with simulated sunlight used to infect cells showed reduced infectivity and reduced viral replication compared to viruses that were not irradiated.

30 Jun 2021

Employed individuals more likely to be infected with the flu virus

A University of Arkansas researcher and international colleagues found that employed individuals, on average, are 35.3% more likely to be infected with the flu virus.

30 Jun 2021

New research receives $2 million grant to determine if meningitis, sepsis increase Alzheimer's risk

The role of peripheral and brain infections in the development of Alzheimer's disease is the focus of new research at The University of Texas Health Science Center at Houston, funded with a $2 million grant from the National Institutes of Health.

30 Jun 2021

Intranasal COVID-19 vaccine developed from bacterial extracellular vesicle induces robust antibody response in preclinical trials

A team of US-based scientists recently developed a novel vaccine candidate against SARS-CoV-2, the causative pathogen of COVID-19. The vaccine is composed of extracellular vesicles of Salmonella typhimurium incorporated with the spike receptor-binding domain (RBD) of SARS-CoV-2. Upon intranasal administration in hamsters, the vaccine induces strong blood antibody titers and protects against severe COVID-19.

30 Jun 2021

Is the SARS-CoV-2 delta variant threatening vaccine efficacy?

A new study in the UK, by researchers at Imperial College London, The Francis Crick Institute and the University of Glasgow, explores the loss of coronavirus disease 2019 (COVID-19) vaccine efficacy against the virus behind the current pandemic caused by the emergence of newer variants that have undergone mutational escape.

30 Jun 2021

Disease/Infection News

Study explores link between threat sensitivity and social conservatism

New article focuses on drug discovery targeting SARS-CoV-2

Scientists reveal the role of newly introduced lineages in COVID-19 resurgence in Europe

Ion channel conserved in coronaviruses a potential new drug target for COVID therapeutics

Study highlights changes within SARS-CoV-2 variants that could be exploited to design effective inhibitors

First demonstration of COVID-19-like response by an essential virus encoded protein by SARS-CoV-2 in vivo

Alpha variant mutations help SARS-CoV-2 overcome evolutionary weaknesses

Behavior modification key to prevent COVID-19, study shows

Novel candidate malaria vaccine confers high levels of durable protection

Frequent testing increases chance of detecting COVID-19 infections

Antibody development against SARS-CoV-2 following Moderna vaccine

Moderna's COVID vaccine effective against emerging variants including Delta

Study provides important insights into early stages of SARS-CoV-2 infection

Sanaria researchers make progress in the development of highly protective malaria vaccine

UC screening program helps detect HIV outbreaks among persons who inject drugs

Solar irradiation inactivates SARS-CoV-2 and other human coronaviruses, finds study

Employed individuals more likely to be infected with the flu virus

New research receives $2 million grant to determine if meningitis, sepsis increase Alzheimer's risk

Intranasal COVID-19 vaccine developed from bacterial extracellular vesicle induces robust antibody response in preclinical trials

Is the SARS-CoV-2 delta variant threatening vaccine efficacy?

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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