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Salivary markers of oxidative stress during severe COVID-19

An interesting study from researchers at the University of Sharjah, Sharjah, United Arab Emirates, presents evidence that an elevated level of expression of oxidant molecules may be correlated with severe infection and lung injury.

2 Jul 2021

B cell depleting agents can cause altered immune responses to COVID-19 vaccines, suggests study

A new preprint, available on the medRxiv* server, describes altered responses to the use of the highly effective messenger RNA (mRNA) vaccines from Pfizer/BioNTech and Moderna in patients with multiple sclerosis on anti-CD20 (MS-aCD20) monotherapy.

2 Jul 2021

What role did the SARS-CoV-2 delta variant play in India’s devastating second wave?

A detailed report, available on the preprint server medRxiv*, describes the various facets of the second wave that set it apart from the first. The report also contains the findings of an extended SIR model that explored the potential effects of intervention at various time points in the second wave.

2 Jul 2021

The use of flavonoids as antiviral agents against SARS-CoV-2

Researchers in Iran have undertaken a comprehensive review of flavonoids and their antiviral potential against SARS-CoV-2.

2 Jul 2021

New $1.7 million project to identify potential COVID-19 treatments

CSIRO, Australia's national science agency, will spearhead a $1.7 million project to identify new treatments for COVID-19, including 'long-COVID'.

2 Jul 2021

Monash expert can discuss the significance of R number in COVID-19 infections

A Monash University expert is available to discuss the significance of rate of virus speed (R number), and how the delta variant R number differs from other COVID-19 strains.

2 Jul 2021

Expanding covid-19 symptom list could help improve the UK’s pandemic response

The UK should expand its official list of symptoms for defining covid-19 to prevent cases being missed and help improve the UK’s pandemic response, say experts in The BMJ today.

2 Jul 2021

Stool transplant may be worth exploring as treatment option for COVID-19

It might be worth exploring stool transplant to treat COVID-19 infection, suggest doctors in a letter published online in the journal Gut, after they used the procedure in two patients to prevent the recurrence of another bacterial infection.

2 Jul 2021

Replication of SARS-CoV-2 in nasal ciliated cells could provide a new vaccination target

Researchers have found that nasal ciliated cells are targeted at the onset of COVID-19 infection, which may help to establish nasal mucosal immunity.

2 Jul 2021

New immunotherapy treatment for cancer patients is more effective and less dangerous

Cell toxicity during immunotherapy is a major limitation to cancer treatment.

2 Jul 2021

Researchers seek to quantify immunogenicity of COVID vaccines in immunocompromised patients

Evidence continues to mount that vaccination against COVID-19, most notably the Pfizer and Moderna vaccines, produces robust, durable protection in the vast majority of recipients.

2 Jul 2021

Immunity to SARS-CoV-2 could last longer than originally believed

One year after infection by SARS-CoV-2, most people maintain anti-Spike antibodies regardless of the severity of their symptoms, according to a study with healthcare workers co-led by the Barcelona Institute for Global Health (ISGlobal), the Catalan Health Institute (ICS) and the Jordi Gol Institute (IDIAP JG), with the collaboration of the Daniel Bravo Andreu Private Foundation.

2 Jul 2021

Hi-tech lab taps advanced technology to boost Singapore's future pandemic response

Nanyang Technological University, Singapore (NTU Singapore) and Pathnova Laboratories, a medical diagnostic company backed by Temasek Life Sciences Accelerator and headquartered in Temasek Life Sciences Laboratory, is contributing to Singapore's COVID-19 diagnostic capability through its partnership in a new clinical diagnostic laboratory.

2 Jul 2021

SwabSeq platform offers a potential solution for massive COVID-19 testing

In an article appearing in Nature Biomedical Engineering, a team of scientists from the UCLA David Geffen School of Medicine and UCLA School of Engineering report real-world results on SwabSeq, a high-throughput testing platform that uses sequencing to test thousands of samples at a time to detect COVID-19.

2 Jul 2021

Research associates prior encounter with seasonal coronavirus to milder COVID-19 symptoms

A study by Stanford University School of Medicine investigators hints that people with COVID-19 may experience milder symptoms if certain cells of their immune systems "remember" previous encounters with seasonal coronaviruses -- the ones that cause about a quarter of the common colds kids get.

2 Jul 2021

Is there a link between circadian rhythms and COVID-19 severity?

This study showed that the time of day of SARS-CoV-2 infection could impact the severity of the viral infection and the host immune response.

1 Jul 2021

Engineered T cells prevent translational shutdown in SARS-CoV-2 infected cells

In a paper recently uploaded to the preprint server bioRxiv* by Schamel et al. (June 25th, 2021) engineered T cells against SARS-CoV-2 are tested against a range of cells in vitro, finding that the treatment could be used to restore cellular immune function and suppress SARS-CoV-2.

1 Jul 2021

Mutations in the spike proteins of SARS-CoV-2 select for amino acid changes, increasing protein stability

A team of researchers recently demonstrated that mutations in the S protein of SARS-CoV-2 select for amino acid changes that result in a more stable protein than would otherwise be expected.

1 Jul 2021

Cryo-EM structure of neutralizing antibody 5-7 in complex with SARS CoV-2 spike

Researchers from the US recently reported the 3.7 Å resolution cryo-EM structure of an NTD-directed neutralizing antibody 5-7 that forms a complex with SARS-CoV-2 spike protein. They also presented the neutralization data against VOC and studied the recognized epitope.

1 Jul 2021

Mustard seed, wall rocket and turmeric extracts show potential against SARS-CoV-2 in vitro

Researchers in Spain have identified plant extracts that may be of interest in the search for treatments of coronavirus disease 2019 (COVID-19) and serve as a basis for future chemical, in vivo, and clinical trials.

1 Jul 2021

Disease/Infection News

Salivary markers of oxidative stress during severe COVID-19

B cell depleting agents can cause altered immune responses to COVID-19 vaccines, suggests study

What role did the SARS-CoV-2 delta variant play in India’s devastating second wave?

The use of flavonoids as antiviral agents against SARS-CoV-2

New $1.7 million project to identify potential COVID-19 treatments

Monash expert can discuss the significance of R number in COVID-19 infections

Expanding covid-19 symptom list could help improve the UK’s pandemic response

Stool transplant may be worth exploring as treatment option for COVID-19

Replication of SARS-CoV-2 in nasal ciliated cells could provide a new vaccination target

New immunotherapy treatment for cancer patients is more effective and less dangerous

Researchers seek to quantify immunogenicity of COVID vaccines in immunocompromised patients

Immunity to SARS-CoV-2 could last longer than originally believed

Hi-tech lab taps advanced technology to boost Singapore's future pandemic response

SwabSeq platform offers a potential solution for massive COVID-19 testing

Research associates prior encounter with seasonal coronavirus to milder COVID-19 symptoms

Is there a link between circadian rhythms and COVID-19 severity?

Engineered T cells prevent translational shutdown in SARS-CoV-2 infected cells

Mutations in the spike proteins of SARS-CoV-2 select for amino acid changes, increasing protein stability

Cryo-EM structure of neutralizing antibody 5-7 in complex with SARS CoV-2 spike

Mustard seed, wall rocket and turmeric extracts show potential against SARS-CoV-2 in vitro

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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