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Nanopore technology allows point-of-care SARS-CoV-2 genomic sequencing

As the SARS-CoV-2 continues to spread worldwide and cause disease and death on a devastating scale, genomic sequencing has become a primary method of keeping track of emerging variants and new outbreaks. A new medRxiv* preprint explores the role of nanopore sequencing in this effort.

14 Jul 2021

Vaccine hesitancy among young adults may stall efforts to achieve herd immunity

Vaccine skepticism among young adults may stall efforts to achieve herd immunity - a threshold in which approximately 80 percent of a population is vaccinated against the coronavirus.

14 Jul 2021

COVID-19 vaccine booster strategy against Delta variant evidence of growing inequity, says WHO

Could the COVID-19 vaccine booster dose strategy being planned in wealthyy nations underscore issues of health inequality?

14 Jul 2021

Fungi and bacteria in the gut may equally impact human health and disease severity

The gut microbiome has received a lot of attention, but research shows that fungi in the gut is also an important microorganism in gut functioning and health.

14 Jul 2021

How has extensive media coverage of AstraZeneca COVID-19 vaccine-related fatal events impacted healthcare services in Norway?

Scientists from Sweden and Norway have recently investigated how media reportage on fatal side-effects of the Oxford-AstraZeneca vaccine has impacted the use of healthcare services among newly vaccinated healthcare workers. The findings reveal that the media reporting has caused a sharp increase in primary and specialist healthcare service utilization by healthcare staff.

14 Jul 2021

Predictive model using vocal features from phone conversations can identify early signs of Alzheimer’s disease

Study shows that a machine learning-based predictive model can be trained using telephone conversations to identify early signs of Alzheimer’s disease.

14 Jul 2021

Is niclosamide a potential SARS-CoV-2 antiviral inhibitor?

Niclosamide is an antihelminthic drug, historically used to treat tapeworm infestations, though has been investigated and repurposed for use against SARS-CoV-2. In a new study recently uploaded to the preprint server bioRxiv* by Garrett et al. (July 12, 2021), the drug demonstrates the ability to reorganize the lipid profile of SARS-CoV-2 infected Vero E6 cells, thereby limiting virus replication.

14 Jul 2021

Researchers examine efficacy of CT-P59 monoclonal antibody against SARS-CoV-2 Brazil variant

The therapeutic monoclonal antibody CT-P59 binds to the RBD of SARS-CoV-2, the site of these three major mutations, which may therefore reduce the potency of this antibody against the P.1 lineage. In a new study, the neutralizing potency of this monoclonal antibody towards both wildtype and P.1 SARS-CoV-2 is investigated. The researchers found that the ability to bind with the virus is impeded by the mutations, resulting in reduced potency in vitro.

14 Jul 2021

Red state, blue state, twin outbreak: Behind Wyoming and Colorado’s anomalous covid spikes

Brandon Graves said covid-19 arrived in Wheatland the way new movies do in this High Plains farming town: months after hitting the big cities and without much fanfare.

14 Jul 2021

People with learning disabilities are at higher risk of covid-19 related hospitalizations, deaths

People with learning disabilities with covid-19 are five times more likely to be admitted to hospital and eight times more likely to die compared with the general population of England, finds a study published by The BMJ today.

14 Jul 2021

Study: COVID-19 has not led to a net increase in smoking unlike other natural disasters

Unlike other population-level stressful events such as natural disasters, COVID-19 has not resulted in a net increase in smoking, according to a new study from the International Tobacco Control (ITC) Project, at the University of Waterloo.

14 Jul 2021

SARS-CoV-2 variants show distinct humoral response and transcriptional profiles in hamster model

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel, highly infectious respiratory virus, and the causative agent of coronavirus disease 2019 (COVID-19) pandemic. SARS-CoV-2, which first originated in Wuhan, in Hubei province of China, is a member of the Coronavirdae family and has a large, non-segmented RNA genome.

14 Jul 2021

SARS-CoV-2 mutations occur in essentially the same locations, research finds

New research from the University of Nebraska-Lincoln has shown that the mutations arising in the COVID-19-causing SARS-CoV-2 virus seem to run in the family -- or at least the genus of coronaviruses most dangerous to humans.

14 Jul 2021

High individual-level variability in SARS-CoV-2 shedding may explain superspreading

Researchers in the United States have provided a high-resolution description of the viral dynamics involved in acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

14 Jul 2021

Study identifies SARS-CoV-2 spike conformation exposing potential new therapeutic targets

Researchers in the United States have demonstrated that the viral spike protein used by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to infect host cells adopts an open conformation exposing novel epitopes that could serve as targets for therapeutic strategies to protect against coronavirus disease 2019 (COVID-19).

14 Jul 2021

Israeli study of breakthrough infections following full BNT-Pfizer vaccination, 40% immunocompromised

Severe forms of coronavirus disease (COVID-19) linked to high mortality rates might arise in a minority of fully-vaccinated individuals with many co-occurring medical conditions, finds a recent study by Israeli researchers published in the journal Clinical Microbiology and Infection.

13 Jul 2021

Disease/Infection News

Nanopore technology allows point-of-care SARS-CoV-2 genomic sequencing

Vaccine hesitancy among young adults may stall efforts to achieve herd immunity

COVID-19 vaccine booster strategy against Delta variant evidence of growing inequity, says WHO

Fungi and bacteria in the gut may equally impact human health and disease severity

How has extensive media coverage of AstraZeneca COVID-19 vaccine-related fatal events impacted healthcare services in Norway?

Predictive model using vocal features from phone conversations can identify early signs of Alzheimer’s disease

Is niclosamide a potential SARS-CoV-2 antiviral inhibitor?

Researchers examine efficacy of CT-P59 monoclonal antibody against SARS-CoV-2 Brazil variant

Red state, blue state, twin outbreak: Behind Wyoming and Colorado’s anomalous covid spikes

People with learning disabilities are at higher risk of covid-19 related hospitalizations, deaths

Study: COVID-19 has not led to a net increase in smoking unlike other natural disasters

SARS-CoV-2 variants show distinct humoral response and transcriptional profiles in hamster model

SARS-CoV-2 mutations occur in essentially the same locations, research finds

High individual-level variability in SARS-CoV-2 shedding may explain superspreading

Study identifies SARS-CoV-2 spike conformation exposing potential new therapeutic targets

Israeli study of breakthrough infections following full BNT-Pfizer vaccination, 40% immunocompromised

Molecular dynamic analysis of SARS-CoV-2 inhibitors

COVID-19 vaccine allocation based on health, socioeconomic factors may help minimize deaths

Wildtype SARS-CoV-2 more widespread in 10-19-year-olds prior to vaccine availability in the USA

Neutralizing aptamers block SARS-CoV-2 infection in vitro

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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