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Modeling study predicts 90 percent drop in COVID-19 deaths following vaccination in US

A new modeling study of the United States suggests that vaccination could markedly reduce the rate of infection, hospitalizations and mortality in the current COVID-19 pandemic – even if confined to adults alone.

2 Dec 2020

Data modeling study assesses effectiveness of NPIs in reducing COVID-19 reproduction number worldwide

As a second wave of the COVID-19 pandemic hits many regions worldwide, a new study reports a method to monitor the effective reproduction number (Re) in near real-time.

2 Dec 2020

Spanish-originated SARS-CoV-2 variant A222V shows rapid spread in Lazio, Italy

A startling new study reports the rapid rise to dominance of a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strain in Italy. This strain, termed the GV clade, is characterized by a single point mutation.

2 Dec 2020

A new potential COVID-19 vaccine candidate: YF-S0

A recent study published in the journal Nature describes the safety and efficacy of a live-attenuated yellow fever 17D (YF17D) vector-based vaccine candidate expressing a non-cleavable form of the spike protein of severe acute respiratory coronavirus 2 (SARS-CoV2).

2 Dec 2020

New and sudden headaches may be a symptom of COVID-19

Researchers report a case of a young male patient who came in with a headache to an emergency room. He had increased intracranial pressure and tested positive for SARS-CoV-2, suggesting new headaches during the pandemic should not be ignored.

2 Dec 2020

Scientists detect a sarbecovirus phylogenetically related to SARS-CoV-2 from bats in Japan

A team of researchers at the University of Tokyo in Japan have detected a sarbecovirus, called Rc-o319, which is phylogenetically positioned in the same clade as SARS-CoV-2 in Rhinolophus cornutus bats in Japan.

2 Dec 2020

Particulate matter levels can play a significant role in SARS-CoV-2 transmission

A new study has found that particulate matter (PM) plays a role in providing surfaces for SARS-CoV-2 transmission and interaction, enabling fomite transmission through deposition.

2 Dec 2020

Two-thirds of parents are worried about the effects of pandemic on children's mental health

Seasons of change can be difficult to navigate emotionally, not only for adults, but also for children. The ongoing COVID-19 pandemic has undoubtedly impacted children's mental health, and as families start planning for the holidays that may look very different this year, it's important to build resilience in kids to prepare them for what's ahead during these winter months.

2 Dec 2020

SARS-CoV-2 deletion mutations may have attenuated infectivity in some strains

A team of researchers at the University of Hong Kong has identified a panel of SARS-CoV-2 variants, called Del-mut, which contains a deletion in the S1/S2 junction. Upon investigating one of the deleted variants in animal models, they found that Del-mut-1 is attenuated in its ability to cause disease or pathological changes.

2 Dec 2020

Autoantigen may help prevent and treat cardiovascular disease

Mitochondrial protein ALDH4A1 has been identified as an autoantigen implicated in atherosclerosis.

2 Dec 2020

Mobile health app can improve HPV vaccine uptake in adolescents

More than 90 percent of human papillomavirus (HPV)-related cancers could be prevented by widespread uptake of the HPV vaccine. Yet, vaccine use in the United States falls short of public health goals.

2 Dec 2020

Study: Integrating palliative care earlier in care trajectory benefits COVID-19 patients

Critical care nurses are ideally positioned to drive full integration of palliative care into the care of all patients who are seriously ill, including patients with COVID-19, according to an article published in the December issue of Critical Care Nurse (CCN).

2 Dec 2020

Elsevier launches a new book on COVID-19

Elsevier, a global research publishing and information analytics provider, recently launched the English version of COVID-19: The Essentials of Prevention and Treatment. A digital version of the book is freely available to download on Elsevier's Novel Coronavirus Information Center here.

2 Dec 2020

New combination therapy may help fight antimicrobial resistance

An inexpensive, FDA-approved drug -- cholestyramine -- taken in conjunction with an antibiotic prevents the antibiotic from driving antimicrobial resistance, according to new research by scientists at Penn State and the University of Michigan. The team's findings appear today (Dec. 1) in the journal eLife.

2 Dec 2020

Researchers evaluate the most appropriate test for COVID-19

Until a vaccine is available, curbing the coronavirus pandemic relies heavily on how quickly a potentially exposed individual can be tested and quarantined.

2 Dec 2020

Study evaluates the performance of meningococcus B vaccine in real-world setting

Meningococcus group B, the most prevalent strain of meningococcal infection, is prevented with 79 per cent effectiveness in children and young adults inoculated with the 4CMenB vaccine, also known as Bexsero.

2 Dec 2020

Breakthrough in microscopy, endoscopy may soon revolutionize the study of cellular origin of diseases

A breakthrough in microscopy and endoscopy will soon revolutionize the study of the cellular origin of diseases, advancing the field of precision medicine. This is the goal of CRIMSON, a trans-disciplinary and trans-national research project recently funded by European Commission.

2 Dec 2020

Pharmacophore model helps find key protease inhibitor responsible for COVID-19

A team of San Diego Supercomputer Center (SDSC) researchers recently created a pharmacophore model and conducted data mining of the database of drugs approved by the U.S. Federal Drug Administration (FDA) to find potential inhibitors of papain-like protease of SARS-CoV2, one of the main viral proteins responsible for COVID-19.

2 Dec 2020

New research project to develop and test novel intervention for individuals with HIV/AIDS

Tulsa CARES is partnering with researchers at the Hudson College of Public Health at the University of Oklahoma Health Sciences Center and the OU-TU School of Community Medicine at the University of Oklahoma to develop and test a novel "food as medicine" intervention for individuals affected by HIV/AIDS.

2 Dec 2020

Study shows how parasite that causes Chagas disease resists current therapies

New insight on how a parasite can resist current therapies has been published today in the open-access eLife journal.

2 Dec 2020

Disease/Infection News

Modeling study predicts 90 percent drop in COVID-19 deaths following vaccination in US

Data modeling study assesses effectiveness of NPIs in reducing COVID-19 reproduction number worldwide

Spanish-originated SARS-CoV-2 variant A222V shows rapid spread in Lazio, Italy

A new potential COVID-19 vaccine candidate: YF-S0

New and sudden headaches may be a symptom of COVID-19

Scientists detect a sarbecovirus phylogenetically related to SARS-CoV-2 from bats in Japan

Particulate matter levels can play a significant role in SARS-CoV-2 transmission

Two-thirds of parents are worried about the effects of pandemic on children's mental health

SARS-CoV-2 deletion mutations may have attenuated infectivity in some strains

Autoantigen may help prevent and treat cardiovascular disease

Mobile health app can improve HPV vaccine uptake in adolescents

Study: Integrating palliative care earlier in care trajectory benefits COVID-19 patients

Elsevier launches a new book on COVID-19

New combination therapy may help fight antimicrobial resistance

Researchers evaluate the most appropriate test for COVID-19

Study evaluates the performance of meningococcus B vaccine in real-world setting

Breakthrough in microscopy, endoscopy may soon revolutionize the study of cellular origin of diseases

Pharmacophore model helps find key protease inhibitor responsible for COVID-19

New research project to develop and test novel intervention for individuals with HIV/AIDS

Study shows how parasite that causes Chagas disease resists current therapies

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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