Disease/Infection News

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Regenstrief dashboard evolves to show COVID-19 trends and early warning indicators

Trends are a vital component of tracking and understanding the COVID-19 outbreak. The COVID-19 dashboard on the Regenstrief Institute website now shows data trends from across Indiana in an easy-to-understand, interactive display.

18 Jun 2020

Study examines the impact of urban density on spread of COVID-19

A new study suggests that denser places, assumed by many to be more conducive to the spread of the coronavirus that causes COVID-19, are not linked to higher infection rates.

18 Jun 2020

Convalescent plasma found to be safe for diverse patients with COVID-19

Mayo Clinic researchers and collaborators have found investigational convalescent plasma to be safe following transfusion in a diverse group of 20,000 patients. The findings -- from the U.S. Food and Drug Administration's Expanded Access Program for COVID-19 -- are reported in Mayo Clinic Proceedings.

18 Jun 2020

Mutational targets of SARS-CoV-2 receptor-binding domain for vaccine-antiviral development

The COVID-19 pandemic has spread throughout the whole world within six months, causing millions of infections and hundreds of thousands of deaths. Yet there is no effective vaccine or antiviral to deal with it.

18 Jun 2020

Crystal structure of SARS-CoV-2 protease-inhibitor in complex with a Chinese herb Shikonin

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has been spreading rampantly over the whole world, infecting millions of people (over 8.45 million at last count), with over 452,000 deaths, as of June 19, 2020. It causes a broad spectrum of disease manifestations, from asymptomatic disease to severe or even fatal respiratory symptoms.

18 Jun 2020

Study reveals how COVID-19 pandemic has impacted cancer patients' quality of life

Patients with cancer face a serious dilemma during the COVID-19 pandemic, as staying at home could increase their risk of cancer progression, while visiting the hospital for treatment could increase their risk of becoming infected with the virus that causes COVID-19.

18 Jun 2020

Neighborhood socioeconomic status and household crowding associated with COVID-19

A study of nearly 400 pregnant women in New York City is among the first to show that lower neighborhood socioeconomic status and greater household crowding increase the risk of becoming infected with SARS-CoV-2, the virus that causes COVID-19.

18 Jun 2020

Novel SARS-CoV-2 antibody cocktail impeccably mimics human antibody response

By using both humanized mice and convalescent patients, the researchers from the US and Singapore successfully generated non-competing and highly potent monoclonal antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein that could potentially be combined to form antibody cocktails. Their groundbreaking paper is published in the leading research journal Science.

18 Jun 2020

Global experts develop open-source N95 face mask

In one of the latest COVID-19 response projects at the University of Massachusetts Amherst, the Advanced Digital Design and Fabrication laboratory is collaborating with a global network of design, engineering and manufacturing experts to help develop an open-source N95 face mask.

18 Jun 2020

Throat gargling may be beneficial during the COVID-19 pandemic

Researchers from Chang Gung University College of Medicine, Taiwan, have suggested that throat gargling may have beneficial effects during the coronavirus disease 2019 (COVID-19) pandemic.

18 Jun 2020

COVID-19 collaborative program reduces mortality in long-term care facilities

A collaborative program developed at UVA Health to work with local long-term care facilities control COVID-19 is saving lives and offers a model for communities across the country, a new scientific paper reports.

18 Jun 2020

First genome-wide CRISPR screen reveals genes that control SARS-CoV-2 infection

By performing a genome-wide CRISPR screen on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), U.S. researchers identified novel proviral genes and pathways, and highlighted host genes that may regulate coronavirus disease (COVID-19) pathogenesis, as well as revealing potential targets for novel treatment approaches. Their findings are currently available on the bioRxiv* preprint server.

18 Jun 2020

COVID-19 pandemic affects sexual and reproductive health of young people

Social distancing and limited access to contraceptive and abortion care during the COVID-19 pandemic is affecting the sexual and reproductive health of adolescents and young adults according to a new study by researchers at Columbia University Mailman School of Public Health and Rutgers University.

18 Jun 2020

COVID-19 pandemic may have negative consequences for mental health

The global COVID-19 pandemic has affected the physical lives of most people. But now there are also indications that the pandemic has negative consequences for the mental health of the people being infected, the healthcare professionals and the population as a whole.

18 Jun 2020

DFG establishes interdisciplinary commission to strengthen pandemic research

Against the background of the current coronavirus pandemic, the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is to establish an interdisciplinary commission for pandemic research.

18 Jun 2020

Certain patients who receive hospital care for COVID-19 exhibit clear signs of brain injury

Certain patients who receive hospital care for coronavirus infection (COVID-19) exhibit clinical and neurochemical signs of brain injury, a University of Gothenburg study shows. In even moderate COVID-19 cases, finding and measuring a blood-based biomarker for brain damage proved to be possible.

18 Jun 2020