Drug Discovery & Pharmaceuticals

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Study illuminates why cowpea mosaic virus is exceptionally effective against cancer

A plant virus that infects legumes, called cowpea mosaic virus, has a special power that you may not have known about: when injected into a tumor, it triggers the immune system to treat the cancer-;even metastatic cancer-;and prevents it from recurring.

27 Apr 2022

MIT researchers develop a smarter method to discover new drugs

Pharmaceutical companies are using artificial intelligence to streamline the process of discovering new medicines.

27 Apr 2022

St. John's wort extract shows potent antiviral activity against SARS-CoV-2 and its variants

Scientists from Germany have recently identified Hypericum perforatum, a widespread herbal plant known as St. John's wort, as a potential antiviral agent against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is published in the journal Pharmaceuticals.

27 Apr 2022

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

As part of World Malaria Day 2022, we interview Karine Le Roch PH.D., about her latest research into how novel antimalarial therapeutic strategies could be on the horizon, after identifying two proteins that are critical to the survival of the malaria parasite, Plasmodium falciparum.

25 Apr 2022

Marine resources could be promising drug candidates against SARS-CoV-2 Omicron

A recent review paper, published in the MDPI’s specialized journal COVID, highlights key features of the Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – and examines the potential and roadblocks in using renewable marine resources in the fight against the coronavirus disease 2019 (COVID-19).

24 Apr 2022

Quercetin and other plant flavonols show anti-SARS-CoV-2 activity

A new study discusses the potential of certain plant compounds to block SARS-CoV-2 replication within host cells.

24 Apr 2022

Texas A&M AgriLife scientists receive grant to fight pesticide-resistant cattle fever ticks

Two projects by Texas A&M AgriLife Research scientists aim to protect the U.S. cattle industry from the emerging threat of pesticide-resistant cattle fever ticks.

21 Apr 2022

Discovery can lead to new antiviral treatments against Crimean-Congo hemorrhagic fever

Researchers at Karolinska Institutet in Sweden have identified key signaling pathways that when blocked by existing drug candidates limit reproduction of the Crimean-Congo hemorrhagic fever (CCHF) virus.

19 Apr 2022

Addition of left-handed chiral gold nanoparticles can enhance vaccine efficacy by more than 25%

Vaccines can be made over 25% more effective by adding left-handed chiral gold nanoparticles as adjuvants, according to a study by an international collaboration in which Brazilian researchers took part. An article reporting the results is published in Nature.

18 Apr 2022

RNA interference triggers that target SARS-CoV-2 genome

Researchers screened ribonucleic acid interference against SARS-CoV-2.

18 Apr 2022

New chemical reaction creates a faster, simpler way of making tertiary amines for medicines

A University of Illinois at Urbana-Champaign research team has discovered a way to produce a special class of molecule that could open the door for new drugs to treat currently untreatable diseases.

15 Apr 2022

New data-driven mechanistic approach can help reduce drug costs and treat diseases

A new data-driven mechanistic approach that predicts cell types within tissue will help to reduce drug costs and treat diseases that were difficult to develop drugs for, according to a West Virginia University scientist.

14 Apr 2022

Venomtech announces new drug development collaboration with Charles River

Venomtech is collaborating with Charles River Laboratories, International Inc. to help drug developers explore venom-derived compounds for a wide range of therapeutic targets.

12 Apr 2022

VectorBuilder to expand with $500 million ‘Gene Delivery Research and Manufacturing Campus

VectorBuilder Inc. has announced the construction of a new R&D and manufacturing center in Guangzhou, China.

From VectorBuilder 12 Apr 2022

NVX-CoV2373 vaccine found to induce functional SARS-CoV-2-specific T cell responses

In a recent study researchers evaluated the T cell responses elicited by full-length severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein vaccine NVX-CoV2373.

12 Apr 2022

Nanocell COVID-19 vaccine elicits potent neutralizing response

A new study describes the high level of neutralizing antibodies elicited by a nanocell vaccine against SARS-CoV-2 in vitro, in vivo, and human studies.

11 Apr 2022

A novel PLpro inhibitor as a broad-spectrum anti-coronavirus agent

Researchers identify a potentially effective compound against COVID-19 against the SARS-CoV-2 PLpro.

10 Apr 2022

MOFs could help improve the delivery of genetic cargo into target cells

Hybrid material helps ferry genetic cargo to target cells. An emerging type of material called a metal-organic framework(MOF) could help improve the delivery of genetic material for treating disease.

10 Apr 2022

High-throughput screening assay could identify new prostate cancer drugs

A novel high-throughput screening assay is designed to identify inhibitors of the androgen receptor, which plays a critical role in the progression of prostate cancer.

6 Apr 2022

UCI researchers reveal the impact of native lipids on rhodopsin signaling and regeneration

In a new study at University of California, Irvine, researchers have revealed the impact of native lipids on rhodopsin signaling and regeneration, which may usher in a new paradigm for discovery of drugs that target G protein-coupled receptors (GPCRs).

6 Apr 2022

Drug Discovery & Pharmaceuticals

Study illuminates why cowpea mosaic virus is exceptionally effective against cancer

MIT researchers develop a smarter method to discover new drugs

St. John's wort extract shows potent antiviral activity against SARS-CoV-2 and its variants

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

Marine resources could be promising drug candidates against SARS-CoV-2 Omicron

Quercetin and other plant flavonols show anti-SARS-CoV-2 activity

Texas A&M AgriLife scientists receive grant to fight pesticide-resistant cattle fever ticks

Discovery can lead to new antiviral treatments against Crimean-Congo hemorrhagic fever

Addition of left-handed chiral gold nanoparticles can enhance vaccine efficacy by more than 25%

RNA interference triggers that target SARS-CoV-2 genome

New chemical reaction creates a faster, simpler way of making tertiary amines for medicines

New data-driven mechanistic approach can help reduce drug costs and treat diseases

Venomtech announces new drug development collaboration with Charles River

VectorBuilder to expand with $500 million ‘Gene Delivery Research and Manufacturing Campus

NVX-CoV2373 vaccine found to induce functional SARS-CoV-2-specific T cell responses

Nanocell COVID-19 vaccine elicits potent neutralizing response

A novel PLpro inhibitor as a broad-spectrum anti-coronavirus agent

MOFs could help improve the delivery of genetic cargo into target cells

High-throughput screening assay could identify new prostate cancer drugs

UCI researchers reveal the impact of native lipids on rhodopsin signaling and regeneration

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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