Drug Discovery & Pharmaceuticals

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Gut bacterium may be an important factor in resistance to antihypertensive medications

Almost half of the U.S. adult population has high blood pressure - or hypertension - and about 20% of these patients have treatment-resistant hypertension.

5 Apr 2022

Natural compound found in cardamom shows promise for treating triple-negative breast cancer

Cardamonin -; a natural compound found in the spice cardamom and other plants -; could have therapeutic potential for triple-negative breast cancer, according to a new study using human cancer cells.

3 Apr 2022

Research demonstrates potential of local siRNA delivery as COVID antiviral therapy in the lung

Scientists develop a formulation for the pulmonary administration of siRNA. The aim was to suppress the replication of SARS-CoV-2.

3 Apr 2022

Phenolic extract from wild blueberries may improve wound healing

Treating wounds with an extract taken from wild blueberries may improve healing, according to a new study.

2 Apr 2022

Chemical in leafy greens could prevent infections by coronaviruses including SARS-CoV-2

Researchers discuss the use of the isothiocyanate sulforaphane for the treatment of both SARS-CoV-2 and HCoV-OC43 infections.

30 Mar 2022

Furin inhibitors as potential therapies to combat SARS-CoV-2 and other diseases

Furin inhibitors as potential therapeutics for treating COVID-19 and other diseases, wherein furin is integral for their pathogenicity and progression.

29 Mar 2022

Utilizing AI to Accelerate the Field of High Content Analysis

In this interview, we speak to Araceli Biosciences about their latest product the Araceli Endeavor, and how its revolutionizing the field of high content screening.

From Society for Laboratory Automation and Screening (SLAS) 29 Mar 2022

CDK6: a potential drug target for severe COVID-19

Researchers identify a methodology and workflow to repurpose drugs against the cyclin-dependent kinase 6 target gene of SARS-CoV-2.

27 Mar 2022

New method for generating binding proteins solves a long-standing challenge in drug development

A team of scientists has created a powerful new method for generating protein drugs. Using computers, they designed molecules that can target important proteins in the body, such as the insulin receptor, as well as vulnerable proteins on the surface of viruses.

25 Mar 2022

Deep-water cone snails produce a potentially painkilling compound, study reports

Scientists already know that the venom of cone snails, which prowl the ocean floor for a fish dinner, contains compounds that can be adapted as pharmaceuticals to treat chronic pain, diabetes and other human maladies.

24 Mar 2022

Scientists develop first drug to treat uncontrolled secretion of mucins in the airways

A multicenter research team co-led by The University of Texas MD Anderson Cancer Center developed the first drug to treat the uncontrolled secretion of mucins in the airways, which causes potentially life-threatening symptoms in millions of Americans with asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF), as well as lung disease resulting from cancer and cancer treatment.

23 Mar 2022

Researchers investigate Galectin-9 as a new treatment target for COVID-19

Researchers discuss alternate therapeutic targets for treating COVID-19 and the effects of Gal-9 on SARS-CoV-2 infection and the immune response.

23 Mar 2022

Study reveals new opportunities for using small molecule drugs to target KRAS mutants

Research published today in Nature Chemical Biology reveals new opportunities for using small molecule drugs to target KRAS, the most commonly mutated protein in cancer.

23 Mar 2022

New approach could lead to quicker generation of effective, personalized cancer vaccines

Scientists have created a pipeline for identifying, prioritizing and evaluating potential tumor antigens for the fast generation of cancer vaccines, according to a report published today in eLife.

22 Mar 2022

Novel nanoparticle-based COVID vaccines induce long-term neutralizing antibody response

Researchers report the results for a new SARS-CoV-2 vaccine currently in Phase III clinical trial known as I53-50.

22 Mar 2022

Powerful tool to monitor membrane proteins trafficking for drug discovery

Inside your body on the surface of cell membranes, a metaphorical communication and traffic network is underway as hormones - or chemical messengers - bind to cell membrane receptors to fine tune how the cell behaves.

22 Mar 2022

CD63-expressing extracellular vesicles neutralize SARS-CoV-2 variants of concern

Researchers evaluate antiviral effects of CD63 tetraspanin extracellular vesicles against SARS-CoV-2 and HIV-1.

22 Mar 2022

Antimalarial drugs are also effective at treating a pulmonary disease, study finds

A research team at Colorado State University has discovered that drugs used to treat malaria are also effective at treating a pulmonary disease similar to tuberculosis.

21 Mar 2022

Research reveals enzyme-driven process that activates anti-cancer molecule

Years of toil in the laboratory have revealed how a marine bacterium makes a potent anti-cancer molecule.

21 Mar 2022

Intranasal delivery of pro-resolving lipid mediators arrests memory loss in experimental Alzheimer’s model

A research collaboration between scientists at LSU Health New Orleans and the Karolinska Institutet in Sweden has found that applying specialized pro-resolving lipid mediators intranasally arrested memory loss and brain degeneration in an experimental model of Alzheimer's Disease (AD).

21 Mar 2022

Drug Discovery & Pharmaceuticals

Gut bacterium may be an important factor in resistance to antihypertensive medications

Natural compound found in cardamom shows promise for treating triple-negative breast cancer

Research demonstrates potential of local siRNA delivery as COVID antiviral therapy in the lung

Phenolic extract from wild blueberries may improve wound healing

Chemical in leafy greens could prevent infections by coronaviruses including SARS-CoV-2

Furin inhibitors as potential therapies to combat SARS-CoV-2 and other diseases

Utilizing AI to Accelerate the Field of High Content Analysis

CDK6: a potential drug target for severe COVID-19

New method for generating binding proteins solves a long-standing challenge in drug development

Deep-water cone snails produce a potentially painkilling compound, study reports

Scientists develop first drug to treat uncontrolled secretion of mucins in the airways

Researchers investigate Galectin-9 as a new treatment target for COVID-19

Study reveals new opportunities for using small molecule drugs to target KRAS mutants

New approach could lead to quicker generation of effective, personalized cancer vaccines

Novel nanoparticle-based COVID vaccines induce long-term neutralizing antibody response

Powerful tool to monitor membrane proteins trafficking for drug discovery

CD63-expressing extracellular vesicles neutralize SARS-CoV-2 variants of concern

Antimalarial drugs are also effective at treating a pulmonary disease, study finds

Research reveals enzyme-driven process that activates anti-cancer molecule

Intranasal delivery of pro-resolving lipid mediators arrests memory loss in experimental Alzheimer’s model

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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