Drug Discovery & Pharmaceuticals

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New nanoparticle SARS-CoV-2 vaccine shows stronger, broader, and more durable protection

The first generation of COVID-19 vaccines have been highly effective, but also have limitations: their efficacy can wane without a booster shot, and they may be less effective against some variants.

2 Feb 2022

New machine-learning model could speed up the process of developing new medicines

Antibodies, small proteins produced by the immune system, can attach to specific parts of a virus to neutralize it.

1 Feb 2022

Potential therapy candidates for patients infected with the SARS-CoV-2 Omicron variant

Researcher discusses several promising therapeutic candidates that have been proposed for the treatment of patients infected with the Omicron variant.

28 Jan 2022

Intranasal interferon-λ treatment protects mice against SARS-CoV-2 Beta and Omicron variants

Researchers investigate the possible efficacy of IFN-λ in the context of SARS-CoV-2 infection in mice.

28 Jan 2022

Targeting CHI3L1 inhibits SARS-CoV-2 variants, including Delta and Omicron

Researchers show that the CHI3L1 inhibitors reduce epithelial cell infection by SARS-CoV-2 VOC pseudovirus moieties.

27 Jan 2022

Peptide-enhanced antibody therapy may help treat breast cancer metastasis to bone

A moderate amount of a peptide-enhanced, biological cancer drug goes a long way in treating breast cancers that metastasize to the bone.

24 Jan 2022

Paxlovid provides a glimpse into the future against SARS-CoV-2

A recent study reveals that nirmatrelvir is potent and effective against the SARS-CoV-2 Omicron variant.

23 Jan 2022

Nano-bubbles containing ACE2 protein can block infection from broad strains of SARS-CoV-2

Scientists at Northwestern Medicine and The University of Texas MD Anderson Cancer Center have identified natural nano-bubbles containing the ACE2 protein (evACE2) in the blood of COVID-19 patients and discovered these nano-sized particles can block infection from broad strains of SARS-CoV-2 virus in preclinical studies.

21 Jan 2022

CENTOGENE teams up with Insilico Medicine to improve therapeutic targets for Niemann-Pick disease type C

A commercial-stage company focused on generating data-driven insights to diagnose, understand and treat rare diseases, and Insilico Medicine, an end-to-end Artificial Intelligence (AI) - driven drug discovery company, today announced a research and development collaboration to accelerate the discovery of novel therapeutic targets for Niemann-Pick disease type C

21 Jan 2022

Discovery illuminates a blueprint to develop new antibiotics for killing bacteria

The Centers for Disease Control and Prevention estimates that more than 2.8 million Americans experience antibiotic-resistant infections each year; more than 35,000 die from those infections.

20 Jan 2022

New cryo-EM method may be able to shortcut a big step in modern vaccine development

Scientists at Scripps Research have devised a method that may be able to shortcut one of the big steps in modern vaccine development.

20 Jan 2022

Natural extracellular vesicles containing ACE2 protein could fight new SARS-CoV-2 variants

Scientists at The University of Texas MD Anderson Cancer Center and Northwestern Medicine have identified natural extracellular vesicles containing the ACE2 protein (evACE2) in the blood of COVID-19 patients that can block infection from broad strains of SARS-CoV-2 virus in preclinical studies. The study was published today in Nature Communications.

20 Jan 2022

Investigational cancer drug mimics the metabolic and therapeutic effects of fasting, mice study shows

An investigational cancer drug that starves tumors of their energy supply also shows evidence of improving whole body metabolism, according to a new study in mice from Washington University School of Medicine in St. Louis.

19 Jan 2022

New mathematical model can calculate the risk of resistance evolution for drug pairs

Bacteria have dangerously evolved to thwart many of the medicines that were designed to kill them. As a result, a growing antibiotic resistance crisis is responsible for more than 700,000 deaths each year, emerging as one of the world's most pressing health issues.

19 Jan 2022

‘Decoy’ protein mitigates lung damage, death induced by aggressive SARS-CoV-2 variants

A drug treatment that acts as a decoy against SARS-CoV-2 was highly effective at preventing death and lung damage in humanized animal models of severe COVID-19 disease, according to a Nature Chemical Biology study from researchers at the University of Illinois Chicago.

19 Jan 2022

New topical cream could help prevent frostbite injuries

Skiers, hikers, soldiers and others exposed to extreme cold temperatures can experience frostbite -; a painful injury that occurs when ice crystals form in the skin. Many extremely cold areas are also remote, and delays in frostbite treatment can result in severe wounds, scarring and even limb amputation

19 Jan 2022

Evaporators assist academic drug discovery

BioChromato Inc reports how the renowned Chemistry Research Laboratories (CRL) at Oxford University (UK) are using several Smart Evaporator C1 units to support their drug discovery activities in therapeutic areas including oncology and regenerative medicine.

From BioChromato Inc. 19 Jan 2022

Drug Discovery & Pharmaceuticals

New nanoparticle SARS-CoV-2 vaccine shows stronger, broader, and more durable protection

New machine-learning model could speed up the process of developing new medicines

Potential therapy candidates for patients infected with the SARS-CoV-2 Omicron variant

Intranasal interferon-λ treatment protects mice against SARS-CoV-2 Beta and Omicron variants

Targeting CHI3L1 inhibits SARS-CoV-2 variants, including Delta and Omicron

Peptide-enhanced antibody therapy may help treat breast cancer metastasis to bone

Paxlovid provides a glimpse into the future against SARS-CoV-2

Nano-bubbles containing ACE2 protein can block infection from broad strains of SARS-CoV-2

CENTOGENE teams up with Insilico Medicine to improve therapeutic targets for Niemann-Pick disease type C

Discovery illuminates a blueprint to develop new antibiotics for killing bacteria

New cryo-EM method may be able to shortcut a big step in modern vaccine development

Natural extracellular vesicles containing ACE2 protein could fight new SARS-CoV-2 variants

Investigational cancer drug mimics the metabolic and therapeutic effects of fasting, mice study shows

New mathematical model can calculate the risk of resistance evolution for drug pairs

‘Decoy’ protein mitigates lung damage, death induced by aggressive SARS-CoV-2 variants

New topical cream could help prevent frostbite injuries

Evaporators assist academic drug discovery

Porter Alliance for Innovative Medicines aims to close the gap between scientific research and clinical care

MD Anderson and Eisbach Bio collaborate to develop precision oncology drugs

Virus-like particles as delivery vehicles for gene-editing

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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