Drug Discovery & Pharmaceuticals

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Salk study could help find better treatment options for colorectal cancer patients

Patients with colorectal cancer were among the first to receive targeted therapies. These drugs aim to block the cancer-causing proteins that trigger out-of-control cell growth while sparing healthy tissues.

14 Dec 2021

Recycling tubular endosomes are associated with effective delivery of mRNA-based therapeutics, study finds

A recent study recently demonstrates the endosomal transport of nanoparticle-based formulations for the effective delivery of mRNA-based therapeutics.

14 Dec 2021

Duke Human Vaccine Institute secures federal contract for advancing investigational vaccines

The National Institute of Allergy and Infectious Diseases awarded researchers at the Duke Human Vaccine Institute a contract that enables it to compete for projects advancing investigational vaccines to production for use in early clinical trials.

14 Dec 2021

Iota-carrageenan inhibits replication of SARS-CoV-2 VOCs

Scientists have recently reported the efficacy of carrageenan against both the SARS-CoV-2 original strain as well as the Alpha, Beta, Gamma, and Delta VOCs.

13 Dec 2021

The antiviral potential of 4′-fluorouridine as an oral treatment against RSV and SARS-CoV-2

New research reports 4’-Fluorouridine (4′-FlU) as an oral antiviral against RSV and SARS-CoV-2.

7 Dec 2021

Poolbeg and University College Dublin sign an Option Agreement to license melioidosis vaccine candidate

Poolbeg Pharma, 'Poolbeg' or the 'Company', a clinical stage infectious disease pharmaceutical company with a capital light clinical model, has signed an Option Agreement to licence MelioVac, a vaccine for melioidosis, with University College Dublin and its inventor, Associate Professor Siobhán McClean, through NovaUCD, the university's knowledge transfer office.

7 Dec 2021

'Combination' adjuvant may boost the protective power of vaccines

Scientists at La Jolla Institute for Immunology and Massachusetts Institute of Technology, have found a possible way to improve the effectiveness of COVID-19 vaccines-;and any vaccine.

4 Dec 2021

New nanoparticle adjuvant could help make vaccines more powerful

A common strategy to make vaccines more powerful is to deliver them along with an adjuvant -; a compound that stimulates the immune system to produce a stronger response.

3 Dec 2021

Green seaweed extract exhibits anti-SARS-CoV-2 activity in vitro

Researchers investigate the antiviral activities of SSPS extracted from green seaweed Ulva sp. to demonstrate the anti-SARS-CoV-2 activity of ulvans.

2 Dec 2021

Freeze-dried liposomes could be used in potential COVID-19 vaccines

Things that are freeze-dried: Astronaut food. Emergency rations. And, just maybe, some future COVID-19 vaccines.

1 Dec 2021

Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting

Researchers in Brazil and Belgium have developed a molecule of pharmaceutical interest from collinein-1, a protein found in rattlesnake venom.

1 Dec 2021

Combination of iota-carrageenan and xylitol as a potential nasal spray for COVID

Researchers determine the inhibition capacity of iota-carrageenan and xylitol in three different candidate preservative-free formulations.

24 Nov 2021

Experimental compound reduces diabetic complications in mice

An experimental compound reduced complications of type 1 and type 2 diabetes in mice—not by lowering blood sugar—but by countering its consequences of cell death, inflammation, and organ damage.

24 Nov 2021

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

A new study evaluates the efficacy of SNX-5422 as a post-exposure prophylactic treatment.

23 Nov 2021

Antigenic cocktail produced in Nicotiana benthamian plant as a potential COVID-19 vaccine candidate

Scientists utilize N. benthamiana for producing the N-protein and an antigenic cocktail containing the N-protein and SARS-CoV-2 S RBD.

23 Nov 2021

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

Riluzole, a drug approved to treat amyotrophic lateral sclerosis (ALS), a disease affecting nerve cells controlling movement, could slow the gradual loss of a particular brain cell that occurs in Niemann-Pick disease type C1 (NPC1), a rare genetic disorder affecting children and adolescents, suggests a study in mice by scientists at the National Institutes of Health.

20 Nov 2021

Drug Discovery & Pharmaceuticals

Salk study could help find better treatment options for colorectal cancer patients

Recycling tubular endosomes are associated with effective delivery of mRNA-based therapeutics, study finds

Duke Human Vaccine Institute secures federal contract for advancing investigational vaccines

Iota-carrageenan inhibits replication of SARS-CoV-2 VOCs

The antiviral potential of 4′-fluorouridine as an oral treatment against RSV and SARS-CoV-2

Poolbeg and University College Dublin sign an Option Agreement to license melioidosis vaccine candidate

'Combination' adjuvant may boost the protective power of vaccines

New nanoparticle adjuvant could help make vaccines more powerful

Green seaweed extract exhibits anti-SARS-CoV-2 activity in vitro

Freeze-dried liposomes could be used in potential COVID-19 vaccines

Protein found in rattlesnake venom used for making a drug candidate to modulate blood clotting

Combination of iota-carrageenan and xylitol as a potential nasal spray for COVID

Experimental compound reduces diabetic complications in mice

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

Antigenic cocktail produced in Nicotiana benthamian plant as a potential COVID-19 vaccine candidate

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

bit.bio appoints Kathryn Corzo as Chief Operating Officer

New target for drug development could fill a major gap in depression treatment

New discovery could lead to the creation of a pan-coronaviruses vaccine

Newly discovered RNA molecule protects mice from emerging SARS-CoV-2 variants

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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