Drug Discovery & Pharmaceuticals

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Celltrion and iProgen Biotech announce partnership for development of novel ADCs

On April 8, Celltrion and the Canada-based iProgen Biotech Inc. announced to agree to partner for the development of novel ADCs against validated antibody targets, including HER2 and CD20.

8 Apr 2019

Inauguration of NIDD, the Neuroimmunology Drug Development Summit

NIDD is the industry’s first meeting dedicated to targeting neuroimmunological mechanisms in order to develop clinically efficacious therapeutics.

From Neuroimmunology Drug Development 5 Apr 2019

Researchers isolate compound that kills drug-resistant fungi from ant microbiota

Antimicrobial and antifungal resistance, which describe the ability of bacteria and other pathogens to resist the effects of drugs to which they were once sensitive, is a major public health problem worldwide.

5 Apr 2019

Researchers use metal-free catalyst to synthesize ketone from aldehyde

Ketones are important organic compounds found in a variety of pharmaceuticals, agrochemicals, and natural products.

4 Apr 2019

Scientists develop new accurate computational method to enhance drug target stability

Scientists from the Moscow Institute of Physics and Technology, the Skolkovo Institute of Science and Technology, and the University of Southern California have developed a new computational method for the design of thermally stable G protein-coupled receptors that are of great help in creating new drugs.

30 Mar 2019

Young scientists develop cheap and simple catalyst system for organic synthesis

The removal of carboxyl groups and the release of alkyl radical fragments from the tight binding of carboxyl groups are one of the most interesting and promising directions in organic synthesis, especially in the field of new drug synthesis.

30 Mar 2019

Queen’s University Belfast and Domainex identify novel first-in-class FLIP inhibitors

Queen’s University Belfast and Domainex are pleased to announce that their joint project team has successfully identified novel first-in-class small molecule inhibitors of the anti-apoptotic protein FLIP.

29 Mar 2019

Cambrex doubles liquid packaging capacity and weekly output at its Québec facility

Cambrex Corporation, the leading small molecule company providing drug substance, drug product and analytical services across the entire drug lifecycle, today announced it will double the liquid packaging capacity and weekly output at its Mirabel, Québec site in Canada with the addition of a cGMP packaging line and a new filler on the existing packaging line.

27 Mar 2019

Probing Submicron Protein Aggregation using Asymmetrical Flow Field-Flow Fractionation, AF4, and Light Scattering

The most recent developments by Wyatt in their instrumentation and software have made the full potential of FFF accessible to a wider user base. In this interview, Kim R. Williams and Christoph Johann talk to News-Medical and Life Sciences about the technologies and their research.

From Waters | Wyatt Technology 27 Mar 2019

Research helps develop new medicines with antibacterial properties

The research, conducted at the CEU UCH, combines molecular typology and QSAR methods as faster and more affordable tools in order to obtain new medicines and challenge the growing appearance of bacterial resistances.

27 Mar 2019

Enamine and Lundbeck announce expansion of drug discovery collaboration

Enamine and H. Lundbeck today announced the expansion of their research collaboration.

From Enamine Ltd 26 Mar 2019

LNC Therapeutics announces grant of Cornell University patent relating to christensenella bacteria

LNC Therapeutics, a French biotech company specializing in gut microbiome-based drug discovery, announced today the grant of the Cornell University (Ithaca, New-York, USA) patent relating to christensenella bacteria.

26 Mar 2019

Cardiff University launches Medicines Discovery Institute to develop new generation of drugs

Cardiff University is stepping up the development of new drugs for mental health and central nervous system conditions, with the launch of the Medicines Discovery Institute.

25 Mar 2019

Metrohm offers latest handheld Raman solution for the pharmaceutical industry

Metrohm is pleased to present the latest compliant handheld Raman solution for the pharmaceutical industry.

From Metrohm USA Inc. 15 Mar 2019

An Insider’s Guide to the chemagic™ Prime™ Junior Instrument

Masoud Toloue from PerkinElmer provides an overview of the chemagic Prime Junior Instrument and gives his inside tips for scientists working with nucleic acids.

From Revvity 14 Mar 2019

Holotomography (HT) technology used to image individual neurons

A Korean research team has demonstrated quantitative morphological profiling of individual neurons using Holotomography (HT) technology developed by Tomocube.

From Tomocube Inc. 14 Mar 2019

Avocado seed extract could be potential source for novel anti-inflammatory compounds

An extract from the seeds of avocados exhibited anti-inflammatory properties in a laboratory study, according to Penn State researchers, and it represents a potential source for novel anti-inflammatory compounds that could be developed as a functional food ingredient or pharmaceuticals.

13 Mar 2019