Drug Discovery & Pharmaceuticals

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New DBTL workflow may enable more efficient production of pharmaceutical raw materials

Researchers in Japan have developed an integrated synthetic biology system to construct new metabolic pathways and enzymes within microbes.

7 May 2019

The endocannabinoid system and skin conditions

a significant amount of research over the past 20 years has demonstrated that the endocannabinoid system plays a vital role in skin homeostasis, and therefore skin conditions too.

7 May 2019

Bioactive compounds in cocoa bean extract could be used to develop new treatment for skeletal diseases

An international team of researchers, led by the University of Granada (UGR) in Spain, has successfully isolated a bioactive compound present in cocoa bean extract that has proven effective in combatting skeletal diseases such as achondroplasia.

7 May 2019

Aptamer Therapeutics collaborates with Cancer Research UK for drug development program

Following the successful awarding of a CRUK Biotherapeutic Drug Discovery Project Award, Aptamer Therapeutics Limited, part of Aptamer Group, is pleased to announce a new collaboration with Dan Wiseman and the Oglesby Leukemia Research Program at the University of Manchester and Cancer Research UK.

From Aptamer Group 6 May 2019

Discovery of small-molecule inhibitors could enable precise control over CRISPR-Cas9 genome editing

The discovery of the first small-molecule inhibitors of the Streptococcus pyogenes Cas9 (SpCas9) protein could enable more precise control over CRISPR-Cas9-based genome editing, researchers report May 2 in the journal Cell.

3 May 2019

New HKBU method could lead to the production of higher quality medicinal drugs

Physics and Chemistry scholars from Hong Kong Baptist University (HKBU) have invented a new method which could speed up the drug discovery process and lead to the production of higher quality medicinal drugs which are purer and have no side effects.

29 Apr 2019

Cannabis, Alcohol and the Epigenome

With the legalization of cannabis in many US states, we explore the epigenetic effects of cannabis, cannabis-derived products, and alcohol.

29 Apr 2019

Uncovering the Structure of HIV Integrase to Inform Drug Discovery

In this interview Dr Kushol Gupta, Research Assistant Professor in the Department of Biochemistry and Biophysics at the Perelman School of Medicine, University of Pennsylvania talks to News-Medical and Life Sciences about the importance of light scattering techniques for investigating structure and mechanism of action in his ongoing research into HIV integrase and the development of HIV therapeutics.

From Waters | Wyatt Technology 24 Apr 2019

Synthesizing Modified and Pharmaceutically Relevant Peptides

In this interview, CEM Corporation talks to News-Medical Life Sciences about using their product the Liberty Blue for Automated High-Efficiency Solid Phase Peptides Synthesis of Modified and Pharmaceutically Relevant Peptides.

From CEM Corporation - Life Science 24 Apr 2019

Key research takeaways from ECCMID 2019

This article aims to provide a brief overview of the key themes of the 29th ECCMID conference and update readers on current research projects.

From ESCMID 19 Apr 2019

Microfluidic-based drug screening chip identifies antibiotic interactions in eight hours

A KAIST research team developed a microfluidic-based drug screening chip that identifies synergistic interactions between two antibiotics in eight hours.

19 Apr 2019

Scientists enter research collaboration to find a cure for cancer

Cancer is a disease that afflicts an alarming number of people, with one in two being diagnosed with a type of cancer during their lifetime.

17 Apr 2019

Researchers create new small molecules that may combat equine encephalitis viruses

Viruses without a preventative vaccine or treatment option pose a looming threat. But for viruses in this category that have already been weaponized and are recognized as human biothreats by the Centers for Disease Control and Prevention, it's a race to find a cure.

17 Apr 2019

Researchers discover new broad-spectrum antibiotic that contains arsenic

Antibiotic resistance has been called one of the biggest public health threats of our time. There is a pressing need for new and novel antibiotics to combat the rise in antibiotic-resistant bacteria worldwide.

16 Apr 2019

Leica Microsystems receives FDA De Novo clearance for blue light fluorescence module

Leica Microsystems has received DeNovo clearance from the FDA to market its FL400 surgical microscope filter in the United States for characterization of tumor tissue in neurosurgery.

From Leica Microsystems GmbH 15 Apr 2019

Hundreds of new anti-cancer drug targets identified using CRISPR

A team of scientists from the Wellcome Sanger Institute have identified the genes that are essential for the survival of thirty types of cancer cells.

11 Apr 2019

GARDP forms multi-actor partnerships to discover new antibiotics

Multi-actor partnership tests natural products and compound libraries for antibacterial activity Discovery efforts will focus on World Health Organization's priority pathogens The Global Antibiotic Research and Development Partnership is partnering with Calibr, the Helmholtz Centre for Infection Research, in particular its location Helmholtz-Institute for Pharmaceutical Research Saarland, and the University of Queensland's Community for Open Antimicrobial Drug Discovery in its efforts to develop and ensure new antibiotics are globally available to all patients who need them.

11 Apr 2019

New molecule could help fight type 2 diabetes and non-alcoholic fatty liver disease

A new molecule -EPB-53-, could help fight type 2 diabetes and the non-alcoholic fatty liver disease, according to a new study led by the team of Manuel Vázquez-Carrera, from the Faculty of Pharmacy and Food Sciences and the Institute of Biomedicine of the University of Barcelona, and the Diabetes and Associated Metabolic Diseases Networking Biomedical Research Center.

10 Apr 2019

Bio-Rad launches new isotype-specific secondary antibodies

Bio-Rad Laboratories, Inc., a global leader of life science research and clinical diagnostic products, today announced the launch of its isotype-specific secondary antibodies.

From Bio-Rad Laboratories 10 Apr 2019

Alcohol, Cannabis and Other Drugs: A Pharmacological Evaluation

Understanding the interactions between alcohol and cannabis can provide researchers, clinicians and other HCPs with important information on the severity of their side effects.

10 Apr 2019

Drug Discovery & Pharmaceuticals

New DBTL workflow may enable more efficient production of pharmaceutical raw materials

The endocannabinoid system and skin conditions

Bioactive compounds in cocoa bean extract could be used to develop new treatment for skeletal diseases

Aptamer Therapeutics collaborates with Cancer Research UK for drug development program

Discovery of small-molecule inhibitors could enable precise control over CRISPR-Cas9 genome editing

New HKBU method could lead to the production of higher quality medicinal drugs

Cannabis, Alcohol and the Epigenome

Uncovering the Structure of HIV Integrase to Inform Drug Discovery

Synthesizing Modified and Pharmaceutically Relevant Peptides

Key research takeaways from ECCMID 2019

Microfluidic-based drug screening chip identifies antibiotic interactions in eight hours

Scientists enter research collaboration to find a cure for cancer

Researchers create new small molecules that may combat equine encephalitis viruses

Researchers discover new broad-spectrum antibiotic that contains arsenic

Leica Microsystems receives FDA De Novo clearance for blue light fluorescence module

Hundreds of new anti-cancer drug targets identified using CRISPR

GARDP forms multi-actor partnerships to discover new antibiotics

New molecule could help fight type 2 diabetes and non-alcoholic fatty liver disease

Bio-Rad launches new isotype-specific secondary antibodies

Alcohol, Cannabis and Other Drugs: A Pharmacological Evaluation

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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