Drug Discovery & Pharmaceuticals

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Scientists develop new class of pain medication without dangerous side effects

Scientists from Freie Universität Berlin and Charité - Universitätsmedizin Berlin at Campus Benjamin Franklin have developed a new class of pain medication.

4 Jul 2017

Study opens new range of therapeutic options for patients with atypical Rett syndrome

A translational, multicenter study carried out by research groups of the Bellvitge Biomedical Research Institute, San Juan de Dios Hospital, the University of Barcelona, Clinic Hospital, the University of Vic, Santa Creu i Sant Pau Hospital and the thematic area of Rare Diseases, has unveiled the potential of D-serine -- a dietary supplement -- to improve the neuronal function of a patient with a mutation of the glutamate receptors associated to atypical Rett syndrome with severe encephalopathy.

4 Jul 2017

Rhodanine-based compounds show inhibitory activity to prevent aggregation of Tau proteins

The design of tailored peptide-polymer conjugates as drug-specific formulation additives offers access to next generation precision additives that can render problematic small organic drugs water-soluble and improve bioavailability.

30 Jun 2017

EPO blood doping has little effect on amateur cyclists’ road race performance

According to a new study published in The Lancet Haematology, recombinant human erythropoietin (rHuEPO), a performance augmenting drug has little effects on high-intensity laboratory cycling test among well-trained amateur cyclists; yet in the laboratory time trial test and endurance road-race up Mont Ventoux (France), the augmenting effects were typically undetectable.

30 Jun 2017

Ondek raises capital to develop new treatment for childhood allergy

Ondek, the Australian biotechnology company founded by Nobel Laureate Professor Barry Marshall, today announced it raised A$3.59 million in equity funding from professional and high-net-worth investors to support his work to develop a new treatment for childhood allergy.

30 Jun 2017

New antiviral drug candidate effective against broad range of coronaviruses

A new antiviral drug candidate inhibits a broad range of coronaviruses, including the SARS and MERS coronaviruses, a multi-institutional team of investigators reports this week in Science Translational Medicine.

29 Jun 2017

Study develops dissolvable microneedle patches for administering influenza vaccine

Study findings published online in The Lancet on June 27, 2017 have found that an experimental patch of dissolving microneedles can produce robust immune responses for influenza. The microneedle patches can be administered safely and can be a substitute for the needle-and-syringe vaccination. With further advancements, they could remove the uneasiness in using an injection and inconvenience of visiting a flu clinic, as well as offering cost benefits.

28 Jun 2017

Study finds more than 50% of opioid prescriptions are distributed for mental disorders

According to a study published in the Journal of the American Board of Family Medicine, of all the opioid medication prescriptions that are distributed annually in the US, more than half are for patients diagnosed for mental illness such as depression and anxiety.

27 Jun 2017

New market dynamics and regulation are key themes 8th Annual Biosimilars Industry Summit

Biosimilar drug manufacturers will no longer need to wait an extra six months after FDA approval to launch their product, following a recent U.S Supreme Court decision. The ruling which allows biosimilar drugs to enter the market faster is expected to save patients and the U.S. health system billions of dollars.[1]

From SAE Media Group 27 Jun 2017

UTEP researchers move one step closer to developing first-ever Chagas disease vaccine

A pair of scientists at The University of Texas at El Paso is one step closer to developing the first ever clinical Chagas disease vaccine.

22 Jun 2017

New algorithm shortens drug discovery times from years to months

An algorithm developed at the Hebrew University cuts through the immense number of possible solutions to shorten drug discovery times from years to months.

22 Jun 2017

African plant extract could pave way for new drug to treat Alzheimer's disease

A plant extract used for centuries in traditional medicine in Nigeria could form the basis of a new drug to treat Alzheimer's disease, researchers at The University of Nottingham have found.

20 Jun 2017

Domainex, Imperial College London expand collaboration to lessen cardiac muscle damage during heart attacks

Domainex Ltd. expands its partnership with Imperial College London, to discover novel therapies that reduce heart muscle damage during heart attacks. The aim is to discover a drug that inhibits the enzyme MAP4K4, which plays a key role in triggering cell death following a heart attack.

19 Jun 2017

Researchers show effective oral treatment option for patients with rheumatoid arthritis

Patients suffering from rheumatoid arthritis are treated for around six months with the standard anti-rheumatic agent methotrexate, to which many patients respond very well.

19 Jun 2017

Research reveals potential treatment to prevent wound scarring

Research at the University of Leicester has revealed a potential treatment to prevent wound scarring that will soon be entering clinical trials.

16 Jun 2017

Investigation evaluates new drug in microgravity to activate immune system, help combat cancer

On Earth, research into antibody-drug conjugates to treat cancer has been around a while. The research presents a problem, though, because Earth-based laboratories aren't able to mimic the shape of the cancer cell within the body, which can sometimes produce incorrect findings.

15 Jun 2017

Scientists discover new approach for antifungal drug treatments

Each year, invasive fungal infections sicken an estimated 2 million people worldwide and kill nearly 800,000 - but a team of international scientists have discovered a new approach for antifungal drug treatments.

15 Jun 2017

Experimental drug suppresses new defective PTEN cancer pathway, study finds

A collaboration between Saïd M. Sebti, Ph.D., chair of Moffitt Cancer Center's Drug Discovery Department, and Michele Pagano, M.D., chair of the Department of Biochemistry and Molecular Pharmacology at New York University's Langone Medical Center, led to the publication of an important study in the latest issue of Nature.

14 Jun 2017

Antibody-based theranostic agent shows promise for identifying and treating pancreatic tumors

Pancreatic cancer is associated with bleak five-year survival rates and limited treatment options, but new research is offering hope.

13 Jun 2017

New way to produce protein antigen may lead to preventative vaccine for schistosomiasis

Cornell and Ludwig Institute for Cancer Research scientists have developed a way to produce a protein antigen that may be useful as vaccine for schistosomiasis – a parasitic disease that infects millions of people, mostly in tropical and subtropical climates – according to new research in the journal Protein Expression and Purification, June 2017.

12 Jun 2017

Drug Discovery & Pharmaceuticals

Scientists develop new class of pain medication without dangerous side effects

Study opens new range of therapeutic options for patients with atypical Rett syndrome

Rhodanine-based compounds show inhibitory activity to prevent aggregation of Tau proteins

EPO blood doping has little effect on amateur cyclists’ road race performance

Ondek raises capital to develop new treatment for childhood allergy

New antiviral drug candidate effective against broad range of coronaviruses

Study develops dissolvable microneedle patches for administering influenza vaccine

Study finds more than 50% of opioid prescriptions are distributed for mental disorders

New market dynamics and regulation are key themes 8th Annual Biosimilars Industry Summit

UTEP researchers move one step closer to developing first-ever Chagas disease vaccine

New algorithm shortens drug discovery times from years to months

African plant extract could pave way for new drug to treat Alzheimer's disease

Domainex, Imperial College London expand collaboration to lessen cardiac muscle damage during heart attacks

Researchers show effective oral treatment option for patients with rheumatoid arthritis

Research reveals potential treatment to prevent wound scarring

Investigation evaluates new drug in microgravity to activate immune system, help combat cancer

Scientists discover new approach for antifungal drug treatments

Experimental drug suppresses new defective PTEN cancer pathway, study finds

Antibody-based theranostic agent shows promise for identifying and treating pancreatic tumors

New way to produce protein antigen may lead to preventative vaccine for schistosomiasis

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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