Drug Discovery & Pharmaceuticals

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New drug offers hope for treatment of aggressive T-PLL leukemia

Hitherto there has been no adequate treatment available for the rare and highly aggressive malignant blood disease T-PLL leukemia.

24 Oct 2017

Northwestern scientists discover 'wasabi receptor' for pain in flatworms

A Northwestern University research team has discovered how scalding heat and tissue injury activate an ancient "pain" receptor in simple animals. The findings could lead to new strategies for analgesic drug design for the treatment of humans.

17 Oct 2017

Investigating new cancer therapy candidates with live-cell imaging

There are two main things that we've worked on in the lab as regards to drug studies. One is identifying new combinations of drugs, and working on why a combination of drugs should work better than each alone.

From Sartorius 16 Oct 2017

Avantor opens new life sciences research and applications laboratory in South Korea

Avantor, a global supplier of ultra-high-purity materials for customers across the life sciences and advanced technologies sectors, recently opened a new life sciences research and applications laboratory in the GwangGyo district, Suwon, South Korea.

16 Oct 2017

TSRI scientists develop molecular model for improving design of osteoporosis treatments

Using advanced mass spectrometry technology, scientists from the Florida campus of The Scripps Research Institute have developed a molecular model that may provide a new framework for improving the design of osteoporosis treatments.

13 Oct 2017

RUDN University scientists synthesize new range of cytotoxic substances

Scientists from RUDN University have synthesized a number of new cytotoxic substances - the ones that can damage cells. In the future the results of the study can be used in cancer therapy.

13 Oct 2017

New generation of drugs targets cancer cells’ vulnerability with broken genes

In recent years, new cancer treatments have brought hope to people who once had limited options. But for others, the wait for an effective drug continues.

12 Oct 2017

Human minibrains expose psychedelic drug effects, study reveals

A Brazilian study has detected variations in signaling pathways that are associated with neurodegeneration, inflammation, and neural plasticity stimulated by a compound from the dimethyltryptamine family known as 5-MeO-DMT.

10 Oct 2017

New webinar highlights importance of data integrity in GxP-regulated laboratories

As regulators continue to tighten their inspection approaches, it is critical for managers and scientists in regulated laboratories to understand the key issues surrounding data integrity and be able to demonstrate compliance.

6 Oct 2017

CGT Catapult’s iPSC line licensed to Universal Cells for creating universal donor cell line

The Cell and Gene Therapy Catapult today announced a non-exclusive licensing agreement to provide its clinical-grade induced Pluripotent Stem Cell line to Seattle based Universal Cells.

6 Oct 2017

Powerful new approach could aid design of better drugs with fewer side-effects

A powerful new way of analyzing how drugs interact with molecules in the body could aid the design of better treatments with fewer side-effects.

5 Oct 2017

Scientists manipulate living cells to produce fluorinated bioplastics

Natural organic compounds that contain fluorine are rare because living organisms—with a few exceptions—do not produce them.

4 Oct 2017

Researchers produce fluorinated molecules in living cells

Natural organic compounds that contain fluorine are rare because living organisms—with a few exceptions—do not produce them. American scientists have now genetically engineered a microbial host for organofluorine metabolism, allowing it to produce a fluoridated intermediate known as a diketide.

30 Sep 2017

University of Hawaii researcher receives $6.3 million grant for trivalent Ebola vaccine development

University of Hawaii vaccine researcher Axel Lehrer, PhD, has received a nearly $6.3 million grant to test whether the Ebola vaccine formula he has developed will protect against two additional viruses in the same family.

28 Sep 2017

Deep Genomics receives $13 million investment to create new class of genetic drugs

Deep Genomics, the AI driven genetic medicine company, received a USD $13 million equity investment led by Khosla Ventures, one of the top venture capital firms. They are accompanied by early stage investment firm True Ventures.

28 Sep 2017

High-speed method generates mini-protein binders with potential to become new class of drugs

Scientists have created a high-speed method to generate thousands of different, small, stable proteins from scratch that can be custom-designed to bind to specific therapeutic targets.

27 Sep 2017

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

My research uses budding yeast as a tool for synthetic biology, and also in chemical and functional genomic applications. We are interested in understanding molecular mechanisms and metabolic pathways of yeast for drug discovery.

From Tecan 27 Sep 2017

SBP researcher awarded $10.8 million grant to pursue development of new drug for substance abuse

Sanford Burnham Prebys Medical Discovery Institute is pleased to announce the National Institute on Drug Abuse at the National Institutes of Health has awarded Nicholas Cosford, Ph.D., a three-year, $10.8 million grant to pursue the preclinical development of a new class of medicine to treat substance use disorders.

26 Sep 2017

Researchers use multi-modal integrated approach to develop potential anti-Chagas therapies

Chagas disease is a potentially life-threatening illness caused by the parasite, Trypanosoma cruzi, and is transmitted to humans through triatomine blood-sucking bugs that are commonly referred to as "kissing bugs" or "vampire bugs".

26 Sep 2017

Advanced technique could pave way for cascade of new steroidal therapeutics

Researchers at Dartmouth College have developed a technique to produce synthetic steroids that could pave the way for a cascade of new drug discoveries. The process, published in the journal Nature Chemistry, facilitates access to rare, mirror-image isomers of naturally occurring steroid structures.

26 Sep 2017

Drug Discovery & Pharmaceuticals

New drug offers hope for treatment of aggressive T-PLL leukemia

Northwestern scientists discover 'wasabi receptor' for pain in flatworms

Investigating new cancer therapy candidates with live-cell imaging

Avantor opens new life sciences research and applications laboratory in South Korea

TSRI scientists develop molecular model for improving design of osteoporosis treatments

RUDN University scientists synthesize new range of cytotoxic substances

New generation of drugs targets cancer cells’ vulnerability with broken genes

Human minibrains expose psychedelic drug effects, study reveals

New webinar highlights importance of data integrity in GxP-regulated laboratories

CGT Catapult’s iPSC line licensed to Universal Cells for creating universal donor cell line

Powerful new approach could aid design of better drugs with fewer side-effects

Scientists manipulate living cells to produce fluorinated bioplastics

Researchers produce fluorinated molecules in living cells

University of Hawaii researcher receives $6.3 million grant for trivalent Ebola vaccine development

Deep Genomics receives $13 million investment to create new class of genetic drugs

High-speed method generates mini-protein binders with potential to become new class of drugs

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

SBP researcher awarded $10.8 million grant to pursue development of new drug for substance abuse

Researchers use multi-modal integrated approach to develop potential anti-Chagas therapies

Advanced technique could pave way for cascade of new steroidal therapeutics

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