Drug Discovery & Pharmaceuticals

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Moffitt researchers develop novel drug that may help combat castration-resistant prostate cancer

Prostate cancer is the third most common cause of cancer-related death in men in the United States. It is estimated that 161,360 men will be diagnosed and more than 26,700 men will die from the disease in this year.

12 Jun 2017

New cancer drug shows promise to treat leukemia in mouse models

Almost 6,000 new cases of acute lymphoblastic leukemia, or ALL, are expected to be diagnosed this year in the United States. The blood cancer can affect both children and adults.

9 Jun 2017

Researchers define action profile of experimental drug intended to treat chronic pain

At high doses, drug candidate BIA 10-2474 binds not only to the protein that it targets, but to other proteins as well. It thus deactivates proteins that are involved in the metabolism of nerve cells.

9 Jun 2017

Without Measurement, There is No Control of Aseptic Processes

An interview with Gilberto Dalmaso, discussing the different grades of pharmaceutical cleanrooms and the production of high level compounds under aseptic conditions.

From Particle Measuring Systems 9 Jun 2017

Southern Research aims to develop new radiosensitizers that may greatly benefit cancer patients

Two out of three cancer patients are treated with radiation, but the therapy often fails to wipe out the tumor or slow its growth. Southern Research is working to develop a new class of drugs that will help the radiation deliver a more powerful punch to the disease.

9 Jun 2017

More-is-better approach appears to improve vaccine protection from HIV-like virus in monkeys

Building on insights from an HIV vaccine regimen in humans that had partial success during a phase 3 clinical trial in Thailand, a Duke-led research team used a more-is-better approach in monkeys that appeared to improve vaccine protection from an HIV-like virus.

8 Jun 2017

SLU scientist discovers cause and potential solution for cancer-related bone pain

In a paper published in the journal Pain, Saint Louis University researcher Daniela Salvemini, Ph.D., reports discovering a key molecular pathway that drives cancer-related bone pain while providing a potential solution with a drug that already is on the market.

8 Jun 2017

Anti-heroin vaccine developed at TSRI proven effective in primate models

A vaccine developed at The Scripps Research Institute (TSRI) to block the "high" of heroin has proven effective in non-human primates. This is the first vaccine against an opioid to pass this stage of preclinical testing.

6 Jun 2017

Research shows new Zika virus vaccine that offers 100% protection in mice

Research presented by Farshad Guirakhoo, Ph.D., Chief Scientific Officer, GeoVax, Inc., at the ASM Microbe 2017 meeting showed a new Zika virus vaccine that gives 100% protection in mice.

5 Jun 2017

University of Redlands researchers discover critical process in pharmaceutical drug development

A faculty-student research team in the chemistry lab at the University of Redlands has advanced a new approach to a critical process in pharmaceutical drug development that could reduce the time and cost of bringing a drug from concept to market.

2 Jun 2017

Scientists create new method to make peptide stapling widely available

UK scientists have created a new method to structure peptides, which they say will be cheaper and make the process of using stapled peptides in drug discovery much more widely available.

2 Jun 2017

Waters collaborates with Wyatt Technology to solve complex molecular characterization challenges

Waters Corporation announced that it entered into a Co-Marketing agreement with Wyatt Technology to advance the analysis of synthetic polymers and biotherapeutic proteins.

2 Jun 2017

Bacterial cell factories produce enzymes that can be used as active ingredients in drugs

Researchers at the Novo Nordisk Foundation Center for Biosustainability in Denmark have developed a method of producing P450 enzymes - used by plants to defend against predators and microbes - in bacterial cell factories. The process could facilitate the production of large quantities of the enzymes, which are also involved in the biosynthesis of active ingredients of cancer drugs.

2 Jun 2017

Yale scientists develop novel chemical process that may lead to creation of new antibiotics

Yale University scientists have developed a novel chemical process that may lead to the creation of a new class of antibiotics.

1 Jun 2017

Researchers discover new class of compounds that inhibit bacterial DNA gyrase

An international team of scientists have discovered a new class of compounds that inhibit bacterial DNA gyrase.

1 Jun 2017

Insilico Medicine launches personalized drug discovery platform to develop new treatments for ALS

Today, Insilico Medicine, Inc., a company applying the latest advances in deep learning to biomarker development, drug discovery and aging research, launched ALS.AI, a personalized drug discovery and biomarker development platform utilizing the latest advances in deep learning.

1 Jun 2017

LimTox online software tool provides information on drug hepatotoxicity

The Biological Text Mining Unit presents in a recent Nucleic Acids Research paper the LimTox online software tool developed at the Spanish National Cancer Research Centre.

1 Jun 2017

Scientists report discovery and validation of drug candidate for treating cryptosporidiosis

Infectious disease scientists from Novartis, the University of Georgia and Washington State University have reported the discovery and early validation of a drug candidate for treating cryptosporidiosis, a diarrheal disease which is a major cause of child mortality in lower-income countries. Currently there are no vaccines or effective treatments.

31 May 2017

Novel vaccine therapy can generate immune responses in patients with HPV-related head and neck cancer

A novel vaccine therapy can generate immune responses in patients with head and neck squamous cell carcinoma (HNSCCa), according to researchers at the Abramson Cancer Center of the University of Pennsylvania.

31 May 2017

Scientists could be one step closer to developing vaccines against viruses

Scientists could be one step closer to developing vaccines against viruses such as Zika, West Nile or HIV, according to Penn State College of Medicine researchers.

31 May 2017

Drug Discovery & Pharmaceuticals

Moffitt researchers develop novel drug that may help combat castration-resistant prostate cancer

New cancer drug shows promise to treat leukemia in mouse models

Researchers define action profile of experimental drug intended to treat chronic pain

Without Measurement, There is No Control of Aseptic Processes

Southern Research aims to develop new radiosensitizers that may greatly benefit cancer patients

More-is-better approach appears to improve vaccine protection from HIV-like virus in monkeys

SLU scientist discovers cause and potential solution for cancer-related bone pain

Anti-heroin vaccine developed at TSRI proven effective in primate models

Research shows new Zika virus vaccine that offers 100% protection in mice

University of Redlands researchers discover critical process in pharmaceutical drug development

Scientists create new method to make peptide stapling widely available

Waters collaborates with Wyatt Technology to solve complex molecular characterization challenges

Bacterial cell factories produce enzymes that can be used as active ingredients in drugs

Yale scientists develop novel chemical process that may lead to creation of new antibiotics

Researchers discover new class of compounds that inhibit bacterial DNA gyrase

Insilico Medicine launches personalized drug discovery platform to develop new treatments for ALS

LimTox online software tool provides information on drug hepatotoxicity

Scientists report discovery and validation of drug candidate for treating cryptosporidiosis

Novel vaccine therapy can generate immune responses in patients with HPV-related head and neck cancer

Scientists could be one step closer to developing vaccines against viruses

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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