Drug Discovery & Pharmaceuticals

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Radboudumc, iMM Lisboa, PATH team up to test new malaria vaccine concept

The Radboud University Medical Center in the Netherlands, the Instituto de Medicina Molecular Lisboa in Portugal, and PATH in Seattle, Washington announced today that they will collaborate to test a new approach to malaria vaccine development in humans for the first time.

31 May 2017

Rice University scientists develop and evaluate analogs of potent cancer fighters

Rice University scientists have developed and evaluated analogs of potent anti-tumor agents known as epothilones using designs and methods that both improve their biological properties and simplify their manufacture.

31 May 2017

Investigational compound inhibits cancer-specific mutations in mice

Many malignancies develop as a result of genetic alterations in individual cells. These gene mutations often cause altered proteins that give new, growth-promoting properties to the cell.

30 May 2017

Radiopharmaceutical for cancer diagnosis is ready for preclinical-phase trial

A radiopharmaceutical for advanced identification of cancer, labeled with the technetium-99 isotope, is ready for the preclinical-phase trial.

30 May 2017

Research findings may pave way for miracle drug to treat narcolepsy

Narcolepsy, a serious sleep disorder in which patients often fall asleep uncontrollably, has been incurable because no effective therapeutic agents are available to date. Recent findings by Japanese scientists in the sleep institute may shed light on this challenging problem.

30 May 2017

New drug offers hope to patients with hepatitis C

Patients with hepatitis C who suffer from advanced stages of liver disease have renewed hope, thanks to findings by researchers who have discovered that a new drug significantly reduces their risk of death and need for transplantation.

26 May 2017

New NMR machine at TSRI’s Florida campus will help advance drug development process

The Nuclear Magnetic Resonance facility at the Florida campus of The Scripps Research Institute is becoming one of the most advanced in South Florida, thanks to a new $600,000 grant from the National Institutes of Health.

26 May 2017

BGU researchers redesign portion of FDA-approved drug into new molecule to treat ALS

Ben-Gurion University of the Negev researchers are developing a new therapy for Amyotrophic Lateral Sclerosis using part of an existing FDA-approved drug that restores the central nervous system's (CNS) immune defenses and increases life expectancy.

25 May 2017

Researchers discover new anti-thrombotic drug target for developing more protective blood thinners

Blood platelets shore up open wounds and help cuts heal, but they can also cause heart attacks and strokes when a congealed ball of platelets known as a thrombus breaks free from a site of injury and gets lodged in blood vessels that feed oxygen to the brain or heart.

24 May 2017

UCLA scientists develop chemical reaction that could yield new fuels and pharmaceuticals

When scientists develop the chemical formulas for new products such as fuels and medications, they often must first create molecules that haven't previously existed.

24 May 2017

Scientists report promising approach to combat influenza and improve survival

The influenza virus turns infected lung cells into factories that churn out thousands of copies of the virus to spread the infection. St. Jude Children's Research Hospital scientists have reported a promising new approach that uses an investigational cancer drug to dial down viral production and dramatically increase survival of flu-infected mice.

23 May 2017

Researchers synthesize lung surfactant by mimicking production of spider silk

Researchers at Karolinska Institutet in Sweden have managed to synthesise lung surfactant, a drug used in the care of preterm babies, by mimicking the production of spider silk.

23 May 2017

UT Southwestern research shows potential of new DNA vaccine in preventing Alzheimer’s disease

A new DNA vaccine when delivered to the skin prompts an immune response that produces antibodies to protect against toxic proteins associated with Alzheimer's disease – without triggering severe brain swelling that earlier antibody treatments caused in some patients.

23 May 2017

New research combines metals and organic acids as viable alternative to antibiotics

Antibiotics are an effective means of treating bacterial contamination. But extensive use of antibiotic substances in medicine and agriculture has resulted in increasingly antibiotic-resistant bacteria.

23 May 2017

Investigational biologic may reduce need for systemic corticosteroids in patients with severe asthma

An investigational biologic may reduce the need for adults with severe asthma to take an oral corticosteroid to control their asthma, according to a randomized controlled trial presented at the ATS 2017 International Conference.

22 May 2017

Supercomputer study of the brain could lead to safer and more effective anesthetics

Researchers have used a supercomputer to show how proteins in the brain control electrical signals, in a breakthrough that could lead to safer and more effective drugs and anesthetics.

22 May 2017

Complex malaria vaccine protects monkeys against virulent parasite strains

Researchers from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, modified an experimental malaria vaccine and showed that it completely protected four of eight monkeys that received it against challenge with the virulent Plasmodium falciparum malaria parasite.

22 May 2017

Scientists to develop drugs for treating cognitive deficits in Huntington's disease sufferers

Scientists at the University of Sussex have started work on a multi-million pound project to develop drugs to treat the debilitating loss of cognitive function associated with Huntington's disease.

19 May 2017

New findings could lead to first broadly effective ebolavirus therapies and vaccines

After analyzing the blood of a survivor of the 2013-16 Ebola outbreak, a team of scientists from academia, industry and the government has discovered the first natural human antibodies that can neutralize and protect animals against all three major disease-causing ebolaviruses.

19 May 2017

Seventh Wave announces collaboration with Yecuris to study new liver disease therapies

Seventh Wave Laboratories, a consulting-based contract research organization that assesses the safety and efficacy of pharmaceutical products and medical devices, has announced an exclusive collaboration with Yecuris Corporation, a global leader in the development and use of humanized models in drug development research.

18 May 2017

Drug Discovery & Pharmaceuticals

Radboudumc, iMM Lisboa, PATH team up to test new malaria vaccine concept

Rice University scientists develop and evaluate analogs of potent cancer fighters

Investigational compound inhibits cancer-specific mutations in mice

Radiopharmaceutical for cancer diagnosis is ready for preclinical-phase trial

Research findings may pave way for miracle drug to treat narcolepsy

New drug offers hope to patients with hepatitis C

New NMR machine at TSRI’s Florida campus will help advance drug development process

BGU researchers redesign portion of FDA-approved drug into new molecule to treat ALS

Researchers discover new anti-thrombotic drug target for developing more protective blood thinners

UCLA scientists develop chemical reaction that could yield new fuels and pharmaceuticals

Scientists report promising approach to combat influenza and improve survival

Researchers synthesize lung surfactant by mimicking production of spider silk

UT Southwestern research shows potential of new DNA vaccine in preventing Alzheimer’s disease

New research combines metals and organic acids as viable alternative to antibiotics

Investigational biologic may reduce need for systemic corticosteroids in patients with severe asthma

Supercomputer study of the brain could lead to safer and more effective anesthetics

Complex malaria vaccine protects monkeys against virulent parasite strains

Scientists to develop drugs for treating cognitive deficits in Huntington's disease sufferers

New findings could lead to first broadly effective ebolavirus therapies and vaccines

Seventh Wave announces collaboration with Yecuris to study new liver disease therapies

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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