Drug Trial News

RSS

A cell's energy level is critical to its survival

In an ongoing effort to fight disease by manipulating energy regulation of cells, a collaborative study led by Dartmouth Medical School (DMS) has demonstrated that cells lacking a tumor-suppressing kinase called LKB1 can still maintain healthy energy levels when they become stressed.

22 Aug 2005

Non-invasive imaging may help predict type 1 diabetes and response to treatment in humans

A key obstacle to early detection of type 1 diabetes - as well as to rapid assessment of the effectiveness of therapeutic intervention - has been the lack of direct, non-invasive technologies to visualize inflammation in the pancreas, an early manifestation of disease.

22 Aug 2005

Novel vaccine strain with high efficacy against tuberculosis

Tuberculosis remains a major global health threat. Although more than 3 billion doses of the BCG vaccine have been administered to fight tuberculosis, the ability of the BCG vaccine to protect adults is very limited, as is its efficacy against newly emerging isolates.

22 Aug 2005

Paroxetine linked to higher rate of suicide

Adult patients taking the antidepressant drug paroxetine are at higher risk of attempting to commit suicide than those not taking medication.

22 Aug 2005

Early clinical signs of ovarian cancer

Many women diagnosed with ovarian cancer actually complained of symptoms of the disease at least four months before they were diagnosed, according to a new study to be published in the October 1, 2005 issue of CANCER, a peer-reviewed journal of the American Cancer Society.

22 Aug 2005

Many phase I trials for new cancer fighting drugs never get reported in peer-reviewed journals

A new study finds many phase I trials for new cancer fighting drugs never get reported in peer-reviewed journals, and says investigators should be committed not just to finding novel compounds, but also to make sure final results of their studies be disseminated to the medical community.

22 Aug 2005

Detailed picture of migraines

Every eight adult Swede suffers from migraine. Using a new method, researchers at Göteborg have managed for the first time ever to provide a detailed picture of an untreated attack. This will be of great significance for the development of new forms of treatment.

22 Aug 2005

Phase I cancer findings under-reported

Phase I cancer studies, trials that are conducted to determine the safety and maximum dose of a new agent, are under-reported in peer-reviewed journals - a trend that could ultimately delay scientific progress and negatively affect patient care, say researchers at The University of Texas M. D. Anderson Cancer Center in a new study out today (Mon., Aug, 22) online in Cancer.

22 Aug 2005

Protein Sirt1 points to new therapies for type 2 diabetes

Opening the possibility of new therapies for type 2 diabetes, researchers at Washington University School of Medicine in St. Louis have found that a protein called Sirt1 enhances the secretion of insulin in mice and allows them to better control blood glucose levels. Their study appears in the August 17 issue of Cell Metabolism.

18 Aug 2005

Magazines aimed at African-American and Hispanic women publish twice as many adverts for potentially health-damaging products

A study published in the open access journal, BMC Public Health, shows that the content of advertisements in black or Latino magazines may contribute to the lower health status observed in African-American and Hispanic populations in the USA.

18 Aug 2005

Chicken pox vaccination has decreased hospitalizations and doctor visits over the last 10 years

Since the introduction of the varicella (chicken pox) vaccine in 1995, hospitalizations and doctor visits because of chicken pox have dropped dramatically, according to a study in the August 17 issue of JAMA: The Journal of the American Medical Association.

18 Aug 2005

Reasons for complications with kidney failure patients

Mayo Clinic researchers searching for explanations of high mortality rates among kidney failure patients undergoing hemodialysis are focusing their attention on the use of heparin, a drug used to reduce clotting of the blood.

18 Aug 2005

Anxiety disorders can compromise success of alcohol-dependence treatment

Individuals who have an anxiety disorder when starting treatment for alcohol dependence have a significantly greater risk for relapse to drinking within four months, according to researchers at the University of Minnesota.

18 Aug 2005

Global prevalence of kidney failure among critically ill patients

A multinational study has found that 5 to 6 percent of patients in intensive care units experience acute kidney failure, and about 60 percent of these patients die in the hospital, according to an article in the August 17 issue of JAMA: The Journal of the American Medical Association.

18 Aug 2005

Separate studies produce conflicting results on race and gender disparities in U.S. health system

Two newly released studies in the U.S. have to some extent come to conflicting results. According to one study, by researchers at Emory University, attempts over the last decade to address race and gender disparities in the treatment of U.S. patients hospitalized for heart attacks, still in some respects raise cause for concern.

18 Aug 2005

Treatment of U.S. patients hospitalized for heart attacks continues to vary according to sex and race

Despite a decade of initiatives to remedy health disparities in cardiovascular medicine, at least some aspects of the treatment of U.S. patients hospitalized for heart attacks continues to vary according to sex and race, according to a study by researchers at Emory University in collaboration with Yale University and other centers.

17 Aug 2005

Long working hours culture drives up the risk of injury and illness

The long working hours culture drives up the risk of injury and illness, reveals a study in Occupational and Environmental Medicine. And the risk has nothing to do with how hazardous the job is, conclude the researchers.

17 Aug 2005

Low hemoglobin levels are a predictor of increased risk of death among heart failure patients

Hemoglobin (Hgb) is the major substance in red blood cells, and its level indicates the blood's ability to carry oxygen throughout the body. Studies have shown that low hemoglobin, which may result in anemia, is more common among patients with heart failure than it is among people in the general population.

17 Aug 2005

Brightly-coloured fruit and veg, may act as antioxidants - protect against rheumatoid arthritis

Rheumatoid arthritis currently affects around 1% adults in the UK. Previous studies have suggested that vitamin C and the pigment beta-cryptoxanthin, both of which are found in brightly-coloured fruit and veg, may act as antioxidants, and protect the body against the oxidative damage which can cause inflammation.

From The University of Manchester 17 Aug 2005

Study shows more obesity-related arthritis among baby boomers

Baby-boomers have spent more years living with more obesity than the previous generation, researchers at Beth Israel Deaconess Medical Center (BIDMC) have found. Although it may be too early to tell whether this will lead to a rise in arthritis rates, the study shows more obesity-related arthritis among baby boomers compared to the previous generation.

17 Aug 2005

Drug Trial News

A cell's energy level is critical to its survival

Non-invasive imaging may help predict type 1 diabetes and response to treatment in humans

Novel vaccine strain with high efficacy against tuberculosis

Paroxetine linked to higher rate of suicide

Early clinical signs of ovarian cancer

Many phase I trials for new cancer fighting drugs never get reported in peer-reviewed journals

Detailed picture of migraines

Phase I cancer findings under-reported

Protein Sirt1 points to new therapies for type 2 diabetes

Magazines aimed at African-American and Hispanic women publish twice as many adverts for potentially health-damaging products

Chicken pox vaccination has decreased hospitalizations and doctor visits over the last 10 years

Reasons for complications with kidney failure patients

Anxiety disorders can compromise success of alcohol-dependence treatment

Global prevalence of kidney failure among critically ill patients

Separate studies produce conflicting results on race and gender disparities in U.S. health system

Treatment of U.S. patients hospitalized for heart attacks continues to vary according to sex and race

Long working hours culture drives up the risk of injury and illness

Low hemoglobin levels are a predictor of increased risk of death among heart failure patients

Brightly-coloured fruit and veg, may act as antioxidants - protect against rheumatoid arthritis

Study shows more obesity-related arthritis among baby boomers

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Latest News