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Tobacco control and healthier diets are key to cutting heart deaths

Encouraging everyone to stop smoking and eat healthier is four times more effective at reducing heart deaths than current government initiatives that target patients who already have heart problems, finds a study published online by the BMJ today

16 Aug 2005

Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Johns Hopkins Kimmel Cancer Center scientists have found that interferon, used for 30 years to treat blood cancers, multiple sclerosis and hepatitis, selectively kills colon cancer cells when combined with another standard chemotherapy agent.

16 Aug 2005

Discovery of gene that controls the speed at which patients develop tuberculosis

Scientists at the Research Institute of the McGill University Health Centre (RI MUHC) have discovered a gene that controls the speed at which patients develop tuberculosis--the first time such a gene has been discovered for this disease.

16 Aug 2005

Proportion of high-risk HPV infections preventable by vaccine may vary by region

Vaccines currently being developed against two types of virus that cause cervical cancer - HPV16 or HPV18 - may prevent a larger proportion of high-risk HPV infections in Europe than sub-Saharan Africa, suggests a study being published online by The Lancet.

16 Aug 2005

Good news for the hundreds of thousands of cancer patients who undergo radiation therapy

Scientists report that they have a better understanding of the complex effects of radiation on tumor biology and that specific radiation treatment regimens may enhance the effectiveness of radiotherapy, even in tumor populations that have been notoriously difficult to treat.

16 Aug 2005

Higher protection sunscreens do not encourage people to spend more time in the sun

Sunbathers wearing sunscreen labeled as "high protection" did not spend more time in the sun during a week-long vacation compared to those wearing "basic protection" sunscreen, according to an article in the August issue of Archives of Dermatology.

16 Aug 2005

Developmental culling and cancer

A new study reveals that a diverse group of apparently unrelated genes that are associated with pheochromocytoma intersect at a common pathway that drives the necessary culling of cells.

16 Aug 2005

Decline in energy production by mitochondria appears to be a key problem leading to insulin resistance

A detectable decline in energy production by mitochondria - the organelles that are the cell's furnace for energy production - seems to be a key problem leading to insulin resistance, and thus to type 2 diabetes, according to studies by Howard Hughes Medical Institute researchers.

16 Aug 2005

New study shows even non-prescription painkillers raise blood pressure in women

According to a new U.S. study women who take higher doses of common, over-the-counter painkillers, such as Ibuprofen and even Tylenol, have higher blood pressure than women who do not.

16 Aug 2005

New hope for those deaf from immune system attack

A new study may one day help those deafened by immune system attack, and possibly also lead to a test that could show which patients may be helped by immediate steroid treatment.

16 Aug 2005

Thousands of young athletes at risk of skin cancer

According to a University of Cincinnati (UC) dermatologist, thousands of young athletes are at high risk of developing skin cancer.

16 Aug 2005

Chronic use of nitroglycerin for chest pain could lead to mitochondrial damage

Definitive evidence to explain how the drug nitroglycerin relieves chest pain has resulted from a new study by Howard Hughes Medical Institute investigators at Duke University Medical Center. Nitroglycerin relaxes blood vessels to boost blood flow, yet the mechanism by which the drug works has remained a matter of scientific controversy.

16 Aug 2005

How patients deal with disparities in patient medical care

A new pilot study out of the University of Cincinnati takes a new look at how patients deal with disparities in patient medical care – disparities that have been documented in hundreds of studies in the past.

16 Aug 2005

Interventions give cancer survivors a greater feeling of control over their health and emotional well-being

Women who receive an educational or nutritional intervention following the completion of their treatment for breast cancer are less likely to be depressed and have a better quality of life than other breast cancer survivors, according to a study by researchers at Carnegie Mellon University, the University of Pittsburgh Medical Center and Emory University.

16 Aug 2005

Nicotine patch dosage can be adjusted to provide more effective treatment for smokers with a history of alcoholism

Tobacco-caused disease is the leading cause of death for patients with alcoholism, but a study led by The Mayo Clinic Nicotine Dependence Center brings hope to non-depressed, recovering alcoholics who also smoke - individualized nicotine patch therapy. The findings were published in the July issue of Journal of Studies on Alcohol.

15 Aug 2005

Gene therapy success for the treatment of congenital muscular dystrophy (CMD) in mice

Researchers from the University of Pittsburgh report the first study to achieve success with gene therapy for the treatment of congenital muscular dystrophy (CMD) in mice, demonstrating that the formidable scientific challenges that have cast doubt on gene therapy ever being feasible for children with muscular dystrophy can be overcome.

15 Aug 2005

How much people eat is in direct relation to how much they are served

If you binged for two weeks while on vacation and gained 5 pounds, would you be biologically primed to eat less to compensate and shake off the excess weight? No, suggests a new Cornell University study.

15 Aug 2005

Complications from angioplasty much lower among patients whose doctors perform a large number of those procedures each year

Before patients get their clogged heart arteries re-opened, they may want to ask their doctor just how many such procedures he or she has done, a new study finds. The answer may make a big difference in each patient's risk of suffering a major setback before leaving the hospital.

15 Aug 2005

Adalimumab and methotrexate is about five times more effective than methotrexate alone for rheumatoid arthritis

For people with long-standing rheumatoid arthritis, combined treatment with the new "biologic" drug adalimumab and methotrexate is about five times more effective than methotrexate alone, according to a new systematic review of studies.

15 Aug 2005

Psychiatric disorders represent an independent risk factor for delay in cancer diagnosis

Patients with psychiatric disorders are diagnosed with esophageal cancer much later and at a more advanced stage than patients with no psychiatric diagnosis, according to a study conducted by researchers in the Oregon Health & Science University Digestive Health Center.

15 Aug 2005

Drug Trial News

Tobacco control and healthier diets are key to cutting heart deaths

Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Discovery of gene that controls the speed at which patients develop tuberculosis

Proportion of high-risk HPV infections preventable by vaccine may vary by region

Good news for the hundreds of thousands of cancer patients who undergo radiation therapy

Higher protection sunscreens do not encourage people to spend more time in the sun

Developmental culling and cancer

Decline in energy production by mitochondria appears to be a key problem leading to insulin resistance

New study shows even non-prescription painkillers raise blood pressure in women

New hope for those deaf from immune system attack

Thousands of young athletes at risk of skin cancer

Chronic use of nitroglycerin for chest pain could lead to mitochondrial damage

How patients deal with disparities in patient medical care

Interventions give cancer survivors a greater feeling of control over their health and emotional well-being

Nicotine patch dosage can be adjusted to provide more effective treatment for smokers with a history of alcoholism

Gene therapy success for the treatment of congenital muscular dystrophy (CMD) in mice

How much people eat is in direct relation to how much they are served

Complications from angioplasty much lower among patients whose doctors perform a large number of those procedures each year

Adalimumab and methotrexate is about five times more effective than methotrexate alone for rheumatoid arthritis

Psychiatric disorders represent an independent risk factor for delay in cancer diagnosis

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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